Correction

DBAASP v.2: an enhanced database of structure and antimicrobial/cytotoxic activity of natural and synthetic peptides (vol 44, pg D1104, 2016)

NUCLEIC ACIDS RESEARCH (2016)

期刊

NUCLEIC ACIDS RESEARCH

卷 44, 期 13, 页码 6503-6503

出版社

OXFORD UNIV PRESS

DOI: 10.1093/nar/gkw243

关键词

-

类别

Biochemistry & Molecular Biology

向作者/读者索取更多资源

Protocol

Reagent

作者

我是这篇论文的作者

点击您的名字以认领此论文并将其添加到您的个人资料中。

推荐

Review Biochemical Research Methods

Web repositories of natural agents promote pests and pathogenic microbes management

Yin Jin, Zheng Wang, An-Yu Dong, Yuan-Qin Huang, Ge-Fei Hao, Bao-An Song

Summary: This study investigated online resources related to insecticides, antimicrobials, medicinal plants, and plant essential oils, showcasing their functionalities, data sources, and applicability. The research also discussed limitations of these resources, providing a valuable toolbox for scientists.

BRIEFINGS IN BIOINFORMATICS (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

The antimicrobial peptide database is 20 years old: Recent developments and future directions

Guangshun Wang

Summary: This article summarizes the timeline and expansions of the Antimicrobial Peptide Database (APD), highlighting new additions and findings. It discusses the importance of the database in antimicrobial development and peptide design, and explores future directions for peptide discovery.

PROTEIN SCIENCE (2023)

添加到收藏夹

Article Medicine, Research & Experimental

Bioprospection of novel synthetic monocurcuminoids: Antioxidant, antimicrobial, and in vitro cytotoxic activities

Milena Mattes Cerveira, Helena Silveira Vianna, Edila Maria Kickhofel Ferrer, Bruno Nunes da Rosa, Claudio Martin Pereira de Pereira, Matheus Dellamea Baldissera, Leonardo Quintana Soares Lopes, Virginia Cielo Rech, Janice Luehring Giongo, Rodrigo de Almeida Vaucher

Summary: The study found that monocurcuminoids (CNs) are a safe and effective alternative for treating microbial infections. In experiments, CNs showed growth-inhibiting effects on various strains of microbes and demonstrated non-toxicity.

BIOMEDICINE & PHARMACOTHERAPY (2021)

添加到收藏夹

Article Fisheries

Tools and techniques for rational designing of antimicrobial peptides for aquaculture

Raja Aadil Hussain Bhat, Dimpal Thakuria, Ritesh Shantilal Tandel, Victoria C. Khangembam, Pragyan Dash, Gayatri Tripathi, Debajit Sarma

Summary: Fisheries and aquaculture industries are crucial for providing food and nutrition to millions of people worldwide. However, the indiscriminate use of antibiotics has resulted in the emergence of antimicrobial-resistant bacteria, posing a significant threat to public health. Researchers suggest that antimicrobial peptides (AMPs) could be an effective alternative to combat antimicrobial resistance in aquaculture.

FISH & SHELLFISH IMMUNOLOGY (2022)

添加到收藏夹

Article Food Science & Technology

The multiverse of action: how mechanisms of synthetic antifungal peptides could be employed in the food industry

Jose J. L. Silva, Maria R. A. de Miranda, Pedro F. N. Souza

Summary: Fungal contamination is a major cause of food spoilage, posing serious risks to human health and economic losses. This review discusses the recent advances in using synthetic peptides as agents to address foodborne fungal resistance and their applications in food preservation.

CURRENT OPINION IN FOOD SCIENCE (2023)

添加到收藏夹

Article Infectious Diseases

Synthetic Antimicrobial Immunomodulatory Peptides: Ongoing Studies and Clinical Trials

Malgorzata Lesiuk, Malgorzata Paduszynska, Katarzyna E. Greber

Summary: Antimicrobial peptides and their synthetic analogs have diverse structures and functions, and can combat infectious diseases while also regulating the immune system. They offer a potential new strategy to address the issue of antimicrobial resistance.

ANTIBIOTICS-BASEL (2022)

添加到收藏夹

Review Chemistry, Medicinal

Marine Cyclic Peptides: Antimicrobial Activity and Synthetic Strategies

Ricardo Ribeiro, Eugenia Pinto, Carla Fernandes, Emilia Sousa

Summary: Marine cyclic peptides are a diverse group of compounds with broad antimicrobial activities, showing promising potential as novel therapeutic agents. These compounds have unique structural characteristics and have demonstrated interesting antimicrobial activities against drug-resistant microorganisms. Marine cyclic peptides are not only potent in vitro, but also show promising results in vivo, making them an important resource for the development of new antimicrobial agents.

MARINE DRUGS (2022)

添加到收藏夹

Article Microbiology

Novel integrated computational AMP discovery approaches highlight diversity in the helminth AMP repertoire

Allister Irvine, Darrin Mckenzie, Ciaran J. McCoy, Robert L. J. Graham, Ciaren Graham, Sharon A. Huws, Louise E. Atkinson, Angela Mousley

Summary: In contrast to nematodes, flatworms do not possess traditional antimicrobial peptides (AMPs), but they have a unique repertoire of cysteine-rich AMP-like peptides. In addition, a computational prediction approach identified eight novel helminth AMP-like peptides with antibacterial activities.

PLOS PATHOGENS (2023)

添加到收藏夹

Review Engineering, Biomedical

Important Roles and Potential Uses of Natural and Synthetic Antimicrobial Peptides (AMPs) in Oral Diseases: Cavity, Periodontal Disease, and Thrush

Albert Donald Luong, Alyah Buzid, John H. T. Luong

Summary: Epithelial cells and leukocytes release AMPs as a defense mechanism against oral pathogens. However, the concentrations of AMPs are low and they are unstable under physiological conditions. Efforts have been made to synthesize stable and low-cytotoxicity AMPs and improve their antimicrobial activity using nanomaterials and biomolecules. Future research should focus on developing AMPs that promote remineralization and antibacterial adhesion. Nanostructured AMPs are a promising alternative to antibiotics due to their broad-spectrum antimicrobial activity and ease of synthesis and modification.

JOURNAL OF FUNCTIONAL BIOMATERIALS (2022)

添加到收藏夹

Review Medicine, Research & Experimental

Synthetic antimicrobial peptides: Characteristics, design, and potential as alternative molecules to overcome microbial resistance

Patricia G. Lima, Jose T. A. Oliveira, Jackson L. Amaral, Cleverson D. T. Freitas, Pedro F. N. Souza

Summary: Synthetic antimicrobial peptides are considered as new weapons against infections caused by multi-drug resistant pathogens. The advances in chemical synthesis have reduced the cost to produce synthetic peptides and open ways to achieve new antimicrobial agents. Therefore, synthetic peptides are new promising molecules to safeguard human and animal health.

LIFE SCIENCES (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Multitalented Synthetic Antimicrobial Peptides and Their Antibacterial, Antifungal and Antiviral Mechanisms

Tania Vanzolini, Michela Bruschi, Andrea C. Rinaldi, Mauro Magnani, Alessandra Fraternale

Summary: This review focuses on synthetic peptides and their multifaceted mechanisms of action as antiviral, antibacterial, and antifungal agents. Synthetic peptides have been shown to affect pathogen structures, disrupt microbial communities, and influence viral life cycles, making them promising tools against emerging infections.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

添加到收藏夹

Article Engineering, Biomedical

Synthetic mucus biomaterials for antimicrobial peptide delivery

Sydney Yang, Gregg A. Duncan

Summary: Researchers have developed a synthetic mucus biomaterial that can deliver LL37 antimicrobial peptides effectively and enhance their therapeutic effect, addressing the limited therapeutic efficacy of AMPs due to rapid degradation and low bioavailability.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2023)

添加到收藏夹

Review Chemistry, Medicinal

Physicochemical Features and Peculiarities of Interaction of AMP with the Membrane

Malak Pirtskhalava, Boris Vishnepolsky, Maya Grigolava, Grigol Managadze

Summary: Antimicrobial peptides (AMPs) have the potential to be novel biotherapeutics with interactions on the cell envelope, requiring comprehensive understanding for rational design. In-depth studies on the physicochemical, aggregative, and structural features of AMPs are essential for accurate classification and effective prediction methods. The knowledge of AMPs' physicochemical properties is crucial for the development of peptide-based antibiotics design tools.

PHARMACEUTICALS (2021)

添加到收藏夹

Article Food Science & Technology

Future of antimicrobial peptides derived from plants in food application-A focus on synthetic peptides

Laila N. Shwaiki, Kieran M. Lynch, Elke K. Arendt

Summary: Synthetic antimicrobial peptides based on plant AMPs are being developed as potential food preservatives, with a focus on enhancing their antimicrobial activity and stability. While the cost of synthesis may be a drawback, advancements in technology may fully exploit the potential role of these synthetic AMPs in combating food spoilage and waste in the long term.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Immunomodulatory Responses of Two Synthetic Peptides against Salmonella Typhimurium Infection

Marco Antonio Ibarra-Valencia, Gerardo Pavel Espino-Solis, Blanca Elisa Estrada, Gerardo Corzo

Summary: The peptides Pin2[G] and FA1 were found to stimulate phagocytosis in in vitro assays, impacting cytokine release and improving the physical condition of mice with gastric infections caused by S. Typhimurium.

MOLECULES (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

DBAASP v.2: an enhanced database of structure and antimicrobial/cytotoxic activity of natural and synthetic peptides

Malak Pirtskhalava, Andrei Gabrielian, Phillip Cruz, Hannah L. Griggs, R. Burke Squires, Darrell E. Hurt, Maia Grigolava, Mindia Chubinidze, George Gogoladze, Boris Vishnepolsky, Vsevolod Alekseev, Alex Rosenthal, Michael Tartakovsky

NUCLEIC ACIDS RESEARCH (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Finding Our Way through Phenotypes

Andrew R. Deans, Suzanna E. Lewis, Eva Huala, Salvatore S. Anzaldo, Michael Ashburner, James P. Balhoff, David C. Blackburn, Judith A. Blake, J. Gordon Burleigh, Bruno Chanet, Laurel D. Cooper, Melanie Courtot, Sandor Csoesz, Hong Cui, Wasila Dahdul, Sandip Das, T. Alexander Dececchi, Agnes Dettai, Rui Diogo, Robert E. Druzinsky, Michel Dumontier, Nico M. Franz, Frank Friedrich, George V. Gkouto, Melissa Haendel, Luke J. Harmon, Terry F. Hayamizu, Yongqun He, Heather M. Hines, Nizar Ibrahim, Laura M. Jackson, Pankaj Jaiswal, Christina James-Zorn, Sebastian Koehler, Guillaume Lecointre, Hilmar Lapp, Carolyn J. Lawrence, Nicolas Le Novere, John G. Lundberg, James Macklin, Austin R. Mast, Peter E. Midford, Istvan Miko, Christopher J. Mungall, Anika Oellrich, David Osumi-Sutherland, Helen Parkinson, Martin J. Ramirez, Stefan Richter, Peter N. Robinson, Alan Ruttenberg, Katja S. Schulz, Erik Segerdell, Katja C. Seltmann, Michael J. Sharkey, Aaron D. Smith, Barry Smith, Chelsea D. Specht, R. Burke Squires, Robert W. Thacker, Anne Thessen, Jose Fernandez-Triana, Mauno Vihinen, Peter D. Vize, Lars Vogt, Christine E. Wall, Ramona L. Walls, Monte Westerfeld, Robert A. Wharton, Christian S. Wirkner, James B. Woolley, Matthew J. Yoder, Aaron M. Zorn, Paula M. Mabee

PLOS BIOLOGY (2015)

添加到收藏夹

Article Microbiology

Whole-Genome Sequencing of Mycobacterium tuberculosis Provides Insight into the Evolution and Genetic Composition of Drug-Resistant Tuberculosis in Belarus

Kurt R. Wollenberg, Christopher A. Desjardins, Aksana Zalutskaya, Vervara Slodovnikova, Andrew J. Oler, Mariam Quinones, Thomas Abeel, Sinead B. Chapman, Michael Tartakovsky, Andrei Gabrielian, Sven Hoffner, Aliaksandr Skrahin, Bruce W. Birren, Alexander Rosenthal, Alena Skrahina, Ashlee M. Earl

JOURNAL OF CLINICAL MICROBIOLOGY (2017)

添加到收藏夹

Article Genetics & Heredity

Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance

Abigail L. Manson, Keira A. Cohen, Thomas Abeel, Christopher A. Desjardins, Derek T. Armstrong, Clifton E. Barry, Jeannette Brand, Sinead B. Chapman, Sang-Nae Cho, Andrei Gabrielian, James Gomez, Andreea M. Jodals, Moses Joloba, Pontus Jureen, Jong Seok Lee, Lesibana Malinga, Mamoudou Maiga, Dale Nordenberg, Ecaterina Noroc, Elena Romancenco, Alex Salazar, Willy Ssengooba, A. A. Velayati, Kathryn Winglee, Aksana Zalutskaya, Laura E. Via, Gail H. Cassell, Susan E. Dorman, Jerrold Ellner, Parissa Farnia, James E. Galagan, Alex Rosenthal, Valeriu Crudu, Daniela Homorodean, Po-Ren Hsueh, Sujatha Narayanan, Alexander S. Pym, Alena Skrahina, Soumya Swaminathan, Martie Van der Walt, David Alland, William R. Bishai, Ted Cohen, Sven Hoffner, Bruce W. Birren, Ashlee M. Earl

NATURE GENETICS (2017)

添加到收藏夹

Article Microbiology

Static and Evolving Norovirus Genotypes: Implications for Epidemiology and Immunity

Gabriel I. Parra, R. Burke Squires, Consolee K. Karangwa, Jordan A. Johnson, Cara J. Lepore, Stanislav V. Sosnovtsev, Kim Y. Green

PLOS PATHOGENS (2017)

添加到收藏夹

Article Cell Biology

PET/CT imaging correlates with treatment outcome in patients with multidrug-resistant tuberculosis

Ray Y. Chen, Lori E. Dodd, Myungsun Lee, Praveen Paripati, Dima A. Hammoud, James M. Mountz, Doosoo Jeon, Nadeem Zia, Homeira Zahiri, M. Teresa Coleman, Matthew W. Carroll, Jong Doo Lee, Yeon Joo Jeong, Peter Herscovitch, Saher Lahouar, Michael Tartakovsky, Alexander Rosenthal, Sandeep Somaiyya, Soyoung Lee, Lisa C. Goldfeder, Ying Cai, Laura E. Via, Seung-Kyu Park, Sang-Nae Cho, Clifton E. Barry

SCIENCE TRANSLATIONAL MEDICINE (2014)

添加到收藏夹

Article Multidisciplinary Sciences

Profiling invasive Plasmodium falciparum merozoites using an integrated omics approach

Krishan Kumar, Prakash Srinivasan, Michael J. Nold, J. Kathleen Moch, Karine Reiter, Dan Sturdevant, Thomas D. Otto, R. Burke Squires, Raul Herrera, Vijayaraj Nagarajan, Julian C. Rayner, Stephen F. Porcella, Scott J. Geromanos, J. David Haynes, David L. Narum

SCIENTIFIC REPORTS (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Radiologist observations of computed tomography (CT) images predict treatment outcome in TB Portals, a real-world database of tuberculosis (TB) cases

Gabriel Rosenfeld, Andrei Gabrielian, Qinlu Wang, Jingwen Gu, Darrell E. Hurt, Alyssa Long, Alex Rosenthal

Summary: The study analyzed TB cases using clinical characteristics, CT images, and radiologist observations from a database, finding that these observations can predict treatment outcomes. It also identified markers of TB disease spread associated with poor treatment outcomes, suggesting the need for further data collection to address potential confounding factors.

PLOS ONE (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections

Miguel Moreno-Molina, Natalia Shubladze, Iza Khurtsilava, Zaza Avaliani, Nino Bablishvili, Manuela Torres-Puente, Luis Villamayor, Andrei Gabrielian, Alex Rosenthal, Cristina Vilaplana, Sebastien Gagneux, Russell R. Kempker, Sergo Vashakidze, Inaki Comas

Summary: Polyclonal infections, where at least two unrelated strains of the same pathogen are detected in an individual, have been linked to worse clinical outcomes in tuberculosis. Analysis of samples from tuberculosis patients in Georgia by Moreno-Molina et al. showed that the magnitude of polyclonal infections may be underestimated when only testing sputum samples.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Article Immunology

Patterns of genomic interrelatedness of publicly available samples in the TB portals database

Kurt R. Wollenberg, Brendan M. Jeffrey, Michael A. Harris, Andrei Gabrielian, Darrell E. Hurt, Alex Rosenthal

Summary: The TB Portals program is an international collaboration that focuses on collecting and disseminating tuberculosis data, with a particular emphasis on drug resistance. By analyzing pathogen genomic data, researchers can gain insights into genetic variations between phylogenomic lineages and explore international transmission. These genomic-relatedness views provide valuable information for further research.

TUBERCULOSIS (2022)

添加到收藏夹

Proceedings Paper Biochemical Research Methods

Methods for Genome-Wide Analysis of MDR and XDR Tuberculosis from Belarus

Roman Sergeev, Ivan Kavaliou, Andrei Gabrielian, Alex Rosenthal, Alexander Tuzikov

BIOINFORMATICS RESEARCH AND APPLICATIONS, ISBRA 2016 (2016)

添加到收藏夹

Article Immunology

Nanopore Sequencing as a Rapidly Deployable Ebola Outbreak Tool

Thomas Hoenen, Allison Groseth, Kyle Rosenke, Robert J. Fischer, Andreas Hoenen, Seth D. Judson, Cynthia Martellaro, Darryl Falzarano, Andrea Marzi, R. Burke Squires, Kurt R. Wollenberg, Emmie de Wit, Joseph Prescott, David Safronetz, Neeltje van Doremalen, Trenton Bushmaker, Friederike Feldmann, Kristin McNally, Fatorma K. Bolay, Barry Fields, Tara Sealy, Mark Rayfield, Stuart T. Nichol, Kathryn C. Zoon, Moses Massaquoi, Vincent J. Munster, Heinz Feldmann

EMERGING INFECTIOUS DISEASES (2016)

添加到收藏夹

暂无数据

© Peeref 2019-2024. All rights reserved.