The CRF1 Antagonist Verucerfont in Anxious Alcohol-Dependent Women: Translation of Neuroendocrine, But not of Anti-Craving Effects

Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress

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Methods for inducing alcohol craving in individuals with co-morbid alcohol dependence and posttraumatic stress disorder: behavioral and physiological outcomes

(2014) Laura E. Kwako et al.   ADDICTION BIOLOGY

The CRH1 Antagonist GSK561679 Increases Human Fear But Not Anxiety as Assessed by Startle

(2014) Christian Grillon et al.   NEUROPSYCHOPHARMACOLOGY

The Corticotropin Releasing Hormone-1 (CRH1) Receptor Antagonist Pexacerfont in Alcohol Dependence: A Randomized Controlled Experimental Medicine Study

(2014) Laura E Kwako et al.   NEUROPSYCHOPHARMACOLOGY

Behavioral, biological, and chemical perspectives on targeting CRF1 receptor antagonists to treat alcoholism

(2013) Eric P. Zorrilla et al.   DRUG AND ALCOHOL DEPENDENCE

Determining target engagement in living systems

(2013) Gabriel M Simon et al.   Nature Chemical Biology

Medications development to treat alcohol dependence: a vision for the next decade

(2012) Raye Z. Litten et al.   ADDICTION BIOLOGY

Prazosin Effects on Stress- and Cue-Induced Craving and Stress Response in Alcohol-Dependent Individuals: Preliminary Findings

(2011) Helen C. Fox et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Effects of Adrenal Sensitivity, Stress- and Cue-Induced Craving, and Anxiety on Subsequent Alcohol Relapse and Treatment Outcomes

(2011) Rajita Sinha   ARCHIVES OF GENERAL PSYCHIATRY

Pharmacogenetic approaches to the treatment of alcohol addiction

(2011) Markus Heilig et al.   NATURE REVIEWS NEUROSCIENCE

Translational and reverse translational research on the role of stress in drug craving and relapse

(2011) Rajita Sinha et al.   PSYCHOPHARMACOLOGY

Discovery of NBI-77860/GSK561679, a potent corticotropin-releasing factor (CRF1) receptor antagonist with improved pharmacokinetic properties

(2010) John E. Tellew et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Multicenter, randomized, double-blind, active comparator and placebo-controlled trial of a corticotropin-releasing factor receptor-1 antagonist in generalized anxiety disorder

(2010) Vladimir Coric et al.   DEPRESSION AND ANXIETY

Synthesis and Structure−Activity Relationships of 8-(Pyrid-3-yl)pyrazolo[1,5-a]-1,3,5-triazines: Potent, Orally Bioavailable Corticotropin Releasing Factor Receptor-1 (CRF1) Antagonists

(2009) Paul J. Gilligan et al.   JOURNAL OF MEDICINAL CHEMISTRY

A 6-Week Randomized, Placebo-Controlled Trial of CP-316,311 (a Selective CRH1Antagonist) in the Treatment of Major Depression

(2008) Brendon Binneman et al.   AMERICAN JOURNAL OF PSYCHIATRY

Neurokinin 1 Receptor Antagonism as a Possible Therapy for Alcoholism

(2008) D. T. George et al.   SCIENCE