Anti-neuroinflammatory Effect of Emodin in LPS-Stimulated Microglia: Involvement of AMPK/Nrf2 Activation

Microglia in Alzheimer’s disease: A multifaceted relationship

(2016) Ayman ElAli et al.   BRAIN BEHAVIOR AND IMMUNITY

Beneficial Effects of Polygonum multiflorum on Hippocampal Neuronal Cells and Mouse Focal Cerebral Ischemia

(2015) Sung Min Ahn et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

AMPK Activation Inhibits Expression of Proinflammatory Mediators Through Downregulation of PI3K/p38 MAPK and NF-κB Signaling in Murine Macrophages

(2015) Bee-Piao Huang et al.   DNA AND CELL BIOLOGY

Deoxysappanone B, a homoisoflavone from the Chinese medicinal plant Caesalpinia sappan L., protects neurons from microglia-mediated inflammatory injuries via inhibition of IκB kinase (IKK)-NF-κB and p38/ERK MAPK pathways

(2015) Ke-Wu Zeng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Microglial HO-1 induction by curcumin provides antioxidant, antineuroinflammatory, and glioprotective effects

(2015) Esther Parada et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Mitochondrial ROS govern the LPS-induced pro-inflammatory response in microglia cells by regulating MAPK and NF-κB pathways

(2015) Junghyung Park et al.   NEUROSCIENCE LETTERS

Lead exposure induced microgliosis and astrogliosis in hippocampus of young mice potentially by triggering TLR4–MyD88–NFκB signaling cascades

(2015) Jin-Tao Liu et al.   TOXICOLOGY LETTERS

Anti-tumor effect of emodin on gynecological cancer cells

(2015) Yaoxian Wang et al.   CELLULAR ONCOLOGY

Toll-Like Receptor 4 Promotes Autonomic Dysfunction, Inflammation and Microglia Activation in the Hypothalamic Paraventricular Nucleus: Role of Endoplasmic Reticulum Stress

(2015) Gustavo S. Masson et al.   PLoS One

CaMKKβ-Dependent Activation of AMP-Activated Protein Kinase Is Critical to Suppressive Effects of Hydrogen Sulfide on Neuroinflammation

(2014) Xiaomei Zhou et al.   ANTIOXIDANTS & REDOX SIGNALING

Tiliroside, a dietary glycosidic flavonoid, inhibits TRAF-6/NF-κB/p38-mediated neuroinflammation in activated BV2 microglia

(2014) Ravikanth Velagapudi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Improvement of functional recovery by chronic metformin treatment is associated with enhanced alternative activation of microglia/macrophages and increased angiogenesis and neurogenesis following experimental stroke

(2014) Qin Jin et al.   BRAIN BEHAVIOR AND IMMUNITY

Emodin inhibits LPS-induced inflammatory response by activating PPAR-γ in mouse mammary epithelial cells

(2014) Zhengtao Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Upregulation of heme oxygenase-1 expression by dehydrodiconiferyl alcohol (DHCA) through the AMPK–Nrf2 dependent pathway

(2014) Junghun Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Crosstalk Between Nrf2 and AMPK Signal Pathways Is Important for the Anti-Inflammatory Effect of Berberine in LPS-Stimulated Macrophages and Endotoxin-Shocked Mice

(2013) Chunfen Mo et al.   ANTIOXIDANTS & REDOX SIGNALING

Anti-inflammatory effects of β-hydroxyisovalerylshikonin in BV2 microglia are mediated through suppression of the PI3K/Akt/NF-kB pathway and activation of the Nrf2/HO-1 pathway

(2013) Rajapaksha Gedara Prasad Tharanga Jayasooriya et al.   FOOD AND CHEMICAL TOXICOLOGY

Quercetin inhibits lipopolysaccharide-induced nitric oxide production in BV2 microglial cells by suppressing the NF-κB pathway and activating the Nrf2-dependent HO-1 pathway

(2013) Chang-Hee Kang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Emodin Regulates Glucose Utilization by Activating AMP-activated Protein Kinase

(2013) Parkyong Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia

(2013) Piotr Przanowski et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Antineuroinflammatory effects of lycopene via activation of adenosine monophosphate-activated protein kinase-α1/heme oxygenase-1 pathways

(2013) Hsiao-Yun Lin et al.   NEUROBIOLOGY OF AGING

Licochalcone E activates Nrf2/antioxidant response element signaling pathway in both neuronal and microglial cells: therapeutic relevance to neurodegenerative disease

(2012) Sa Suk Kim et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Endotoxin-activated microglia injure brain derived endothelial cells via NF-κB, JAK-STAT and JNK stress kinase pathways

(2011) Rachid Kacimi et al.   Journal of Inflammation-London

Inhibitory effects of melatonin on the lipopolysaccharide-induced CC chemokine expression in BV2 murine microglial cells are mediated by suppression of Akt-induced NF-κB and STAT/GAS activity

(2011) Kyoung-Jin Min et al.   JOURNAL OF PINEAL RESEARCH

Anti-inflammatory activity of xanthohumol involves heme oxygenase-1 induction via NRF2-ARE signaling in microglial BV2 cells

(2010) Ik-Soo Lee et al.   NEUROCHEMISTRY INTERNATIONAL