Nuclear receptors outside the nucleus: extranuclear signalling by steroid receptors

Membrane and nuclear estrogen receptor α collaborate to suppress adipogenesis but not triglyceride content

(2016) Ali Pedram et al.   FASEB JOURNAL

Progesterone generates cancer stem cells through membrane progesterone receptor-triggered signaling in basal-like human mammary cells

(2015) Guillaume Vares et al.   CANCER LETTERS

Progesterone receptor membrane component 1 deficiency attenuates growth while promoting chemosensitivity of human endometrial xenograft tumors

(2015) Anne M. Friel et al.   CANCER LETTERS

Estrogen Receptor β Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis

(2015) Sang Jun Han et al.   CELL

Rapid Nongenomic Glucocorticoid Actions in Male Mouse Hypothalamic Neuroendocrine Cells Are Dependent on the Nuclear Glucocorticoid Receptor

(2015) Jebun Nahar et al.   ENDOCRINOLOGY

Progesterone receptor membrane component-1 regulates hepcidin biosynthesis

(2015) Xiang Li et al.   JOURNAL OF CLINICAL INVESTIGATION

The G-protein coupled estrogen receptor, GPER: The inside and inside-out story

(2015) H.M. Gaudet et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Structural and Functional Evidence for Testosterone Activation of GPRC6A in Peripheral Tissues

(2015) Min Pi et al.   MOLECULAR ENDOCRINOLOGY

Activated retinoid receptors are required for the migration and fate maintenance of subsets of cortical neurons

(2014) J. Choi et al.   DEVELOPMENT

Membrane-Localized Estrogen Receptor α Is Required for Normal Organ Development and Function

(2014) Ali Pedram et al.   DEVELOPMENTAL CELL

Complexities of androgen receptor signalling in breast cancer

(2014) Keely M McNamara et al.   ENDOCRINE-RELATED CANCER

A Rapid Cytoplasmic Mechanism for PI3 Kinase Regulation by the Nuclear Thyroid Hormone Receptor, TRβ, and Genetic Evidence for Its Role in the Maturation of Mouse Hippocampal Synapses In Vivo

(2014) Negin P. Martin et al.   ENDOCRINOLOGY

Caveolin-1 Regulates Genomic Action of the Glucocorticoid Receptor in Neural Stem Cells

(2014) M. E. Peffer et al.   MOLECULAR AND CELLULAR BIOLOGY

Progesterone receptor-B enhances estrogen responsiveness of breast cancer cells via scaffolding PELP1- and estrogen receptor-containing transcription complexes

(2014) A R Daniel et al.   ONCOGENE

Lysosomal Function Is Involved in 17β-Estradiol-Induced Estrogen Receptor α Degradation and Cell Proliferation

(2014) Pierangela Totta et al.   PLoS One

Androgens regulate ovarian follicular development by increasing follicle stimulating hormone receptor and microRNA-125b expression

(2014) A. Sen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nongenomic Thyroid Hormone Signaling Occurs Through a Plasma Membrane-Localized Receptor

(2014) H. Kalyanaraman et al.   Science Signaling

PPARγ and the global map of adipogenesis and beyond

(2014) Martina I. Lefterova et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

mTORC2 in the center of cancer metabolic reprogramming

(2014) Kenta Masui et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Reprogramming of non-genomic estrogen signaling by the stemness factor SOX2 enhances the tumor-initiating capacity of breast cancer cells

(2013) Alejandro Vazquez-Martin et al.   CELL CYCLE

The Role of Estrogens in Control of Energy Balance and Glucose Homeostasis

(2013) Franck Mauvais-Jarvis et al.   ENDOCRINE REVIEWS

LXRβ/estrogen receptor-α signaling in lipid rafts preserves endothelial integrity

(2013) Tomonori Ishikawa et al.   JOURNAL OF CLINICAL INVESTIGATION

Estrogen regulates histone deacetylases to prevent cardiac hypertrophy

(2013) Ali Pedram et al.   MOLECULAR BIOLOGY OF THE CELL

Minireview: Dynamic Structures of Nuclear Hormone Receptors: New Promises and Challenges

(2013) S. Stoney Simons et al.   MOLECULAR ENDOCRINOLOGY

Mutation of the palmitoylation site of estrogen receptor   in vivo reveals tissue-specific roles for membrane versus nuclear actions

(2013) M. Adlanmerini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocorticoids and their receptors: Insights into specific roles in mitochondria

(2013) Sung-Ryul Lee et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Brain region- and sex-specific modulation of mitochondrial glucocorticoid receptor phosphorylation in fluoxetine treated stressed rats: Effects on energy metabolism

(2013) Miroslav Adzic et al.   PSYCHONEUROENDOCRINOLOGY

Estrogen Reduces Lipid Content in the Liver Exclusively from Membrane Receptor Signaling

(2013) A. Pedram et al.   Science Signaling

Phosphorylation: a fundamental regulator of steroid receptor action

(2013) Lindsey S. Treviño et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

27-Hydroxycholesterol Promotes Cell-Autonomous, ER-Positive Breast Cancer Growth

(2013) Qian Wu et al.   Cell Reports

Molecular Mechanisms of Estrogen Receptors' Suppression of Lipogenesis in Pancreatic β-Cells

(2012) Joseph P. Tiano et al.   ENDOCRINOLOGY

Paxillin mediates extranuclear and intranuclear signaling in prostate cancer proliferation

(2012) Aritro Sen et al.   JOURNAL OF CLINICAL INVESTIGATION

Phosphorylation by p38 Mitogen-Activated Protein Kinase Promotes Estrogen Receptor   Turnover and Functional Activity via the SCFSkp2 Proteasomal Complex

(2012) S. Bhatt et al.   MOLECULAR AND CELLULAR BIOLOGY

Estrogen Modulates Metabolic Pathway Adaptation to Available Glucose in Breast Cancer Cells

(2012) Fiona O'Mahony et al.   MOLECULAR ENDOCRINOLOGY

Tamoxifen regulates cell fate through mitochondrial estrogen receptor beta in breast cancer

(2012) M Razandi et al.   ONCOGENE

Glucocorticoid and Estrogen Receptors Are Reduced in Mitochondria of Lung Epithelial Cells in Asthma

(2012) Davina C. M. Simoes et al.   PLoS One

Mechanisms Underlying Rapid Aldosterone Effects in the Kidney

(2011) Warren Thomas et al.   Annual Review of Physiology

Selective Mutations in Estrogen Receptor α D-domain Alters Nuclear Translocation and Non-estrogen Response Element Gene Regulatory Mechanisms

(2011) Katherine A. Burns et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes

(2011) Joseph P. Tiano et al.   JOURNAL OF CLINICAL INVESTIGATION

DHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptors

(2011) Ali Pedram et al.   MOLECULAR BIOLOGY OF THE CELL

Glucocorticoid receptor stimulation and the regulation of neonatal cerebellar neural progenitor cell apoptosis

(2011) Kevin K. Noguchi et al.   NEUROBIOLOGY OF DISEASE

Long-lasting behavioral responses to stress involve a direct interaction of glucocorticoid receptors with ERK1/2-MSK1-Elk-1 signaling

(2011) M. Gutierrez-Mecinas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

27-Hydroxycholesterol: the first identified endogenous SERM

(2011) Michihisa Umetani et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Insulin-Mediated Acceleration of Breast Cancer Development and Progression in a Nonobese Model of Type 2 Diabetes

(2010) R. Novosyadlyy et al.   CANCER RESEARCH

Paxillin Regulates Androgen- and Epidermal Growth Factor-induced MAPK Signaling and Cell Proliferation in Prostate Cancer Cells

(2010) Aritro Sen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estradiol Induces Export of Sphingosine 1-Phosphate from Breast Cancer Cells via ABCC1 and ABCG2

(2010) Kazuaki Takabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GPRC6A Mediates the Non-genomic Effects of Steroids

(2010) Min Pi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heat Shock Protein 27 Is Required for Sex Steroid Receptor Trafficking to and Functioning at the Plasma Membrane

(2010) M. Razandi et al.   MOLECULAR AND CELLULAR BIOLOGY

Granulosa Cell-Specific Androgen Receptors Are Critical Regulators of Ovarian Development and Function

(2010) Aritro Sen et al.   MOLECULAR ENDOCRINOLOGY

Xenoestrogen-Induced Regulation of EZH2 and Histone Methylation via Estrogen Receptor Signaling to PI3K/AKT

(2010) Tiffany G. Bredfeldt et al.   MOLECULAR ENDOCRINOLOGY

Estrogen Receptor-β Prevents Cardiac Fibrosis

(2010) Ali Pedram et al.   MOLECULAR ENDOCRINOLOGY

Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology

(2010) B. York et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extranuclear estrogen receptor-  stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis

(2010) W. P. S. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hormone Action in the Mammary Gland

(2010) C. Brisken et al.   Cold Spring Harbor Perspectives in Biology

Insulin-Sensitizing Therapy Attenuates Type 2 Diabetes-Mediated Mammary Tumor Progression

(2009) Y. Fierz et al.   DIABETES

Progesterone Receptor A (PRA) and PRB-Independent Effects of Progesterone on Gonadotropin-Releasing Hormone Release

(2009) Nicole Sleiter et al.   ENDOCRINOLOGY

Rapid Regulation of KATPChannel Activity by 17β-Estradiol in Pancreatic β-Cells Involves the Estrogen Receptor β and the Atrial Natriuretic Peptide Receptor

(2009) Sergi Soriano et al.   MOLECULAR ENDOCRINOLOGY

The Vitamin D Sterol-Vitamin D Receptor Ensemble Model Offers Unique Insights into Both Genomic and Rapid-Response Signaling

(2009) M. T. Mizwicki et al.   Science Signaling

GPR30 Does Not Mediate Estrogenic Responses in Reproductive Organs in Mice

(2008) Christiane Otto et al.   BIOLOGY OF REPRODUCTION

G Protein-Coupled Receptor 30 Localizes to the Endoplasmic Reticulum and Is Not Activated by Estradiol

(2008) Christiane Otto et al.   ENDOCRINOLOGY

The Nutritional Flavanone Naringenin Triggers Antiestrogenic Effects by Regulating Estrogen Receptor α-Palmitoylation

(2008) Paola Galluzzo et al.   ENDOCRINOLOGY

Expression Pattern of G Protein-Coupled Receptor 30 in LacZ Reporter Mice

(2008) Jörg Isensee et al.   ENDOCRINOLOGY

EF Domains Are Sufficient for Nongenomic Mineralocorticoid Receptor Actions

(2008) Claudia Grossmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Developmental Phenotype of a Membrane Only Estrogen Receptor α (MOER) Mouse

(2008) Ali Pedram et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear and Extranuclear Pathway Inputs in the Regulation of Global Gene Expression by Estrogen Receptors

(2008) Zeynep Madak-Erdogan et al.   MOLECULAR ENDOCRINOLOGY