Advances in the molecular genetics of gliomas — implications for classification and therapy
出版年份 2016 全文链接
标题
Advances in the molecular genetics of gliomas — implications for classification and therapy
作者
关键词
-
出版物
Nature Reviews Clinical Oncology
Volume 14, Issue 7, Pages 434-452
出版商
Springer Nature
发表日期
2016-12-29
DOI
10.1038/nrclinonc.2016.204
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Vascular, glial, and lymphatic immune gateways of the central nervous system
- (2016) Britta Engelhardt et al. ACTA NEUROPATHOLOGICA
- Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology
- (2016) Ibrahim Qaddoumi et al. ACTA NEUROPATHOLOGICA
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- CNS tumoursThe first study of dabrafenib in pediatric patients with BRAF V600–mutant relapsed or refractory low-grade gliomas
- (2016) M.W. Kieran et al. ANNALS OF ONCOLOGY
- Glioblastoma in the Canton of Zurich, Switzerland revisited: 2005 to 2009
- (2016) Dorothee Gramatzki et al. CANCER
- Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma
- (2016) Michele Ceccarelli et al. CELL
- Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial
- (2016) R. Xu et al. CLINICAL CANCER RESEARCH
- Phase II Study of Radiotherapy and Temsirolimus versus Radiochemotherapy with Temozolomide in Patients with Newly Diagnosed Glioblastoma without MGMT Promoter Hypermethylation (EORTC 26082)
- (2016) W. Wick et al. CLINICAL CANCER RESEARCH
- Next-generation personalised medicine for high-risk paediatric cancer patients – The INFORM pilot study
- (2016) Barbara C. Worst et al. EUROPEAN JOURNAL OF CANCER
- A phase III randomized controlled trial of short-course radiotherapy with or without concomitant and adjuvant temozolomide in elderly patients with glioblastoma (CCTG CE.6, EORTC 26062-22061, TROG 08.02, NCT00482677).
- (2016) James R. Perry et al. JOURNAL OF CLINICAL ONCOLOGY
- Results of the interim analysis of the EORTC randomized phase III CATNON trial on concurrent and adjuvant temozolomide in anaplastic glioma without 1p/19q co-deletion: An Intergroup trial.
- (2016) Martin J. Van Den Bent et al. JOURNAL OF CLINICAL ONCOLOGY
- Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency
- (2016) Eric Bouffet et al. JOURNAL OF CLINICAL ONCOLOGY
- Successful Treatment of a ProgressiveBRAFV600E–Mutated Anaplastic Pleomorphic Xanthoastrocytoma With Vemurafenib Monotherapy
- (2016) Eudocia Q. Lee et al. JOURNAL OF CLINICAL ONCOLOGY
- Sensitivity Analysis of the MGMT-STP27 Model and Impact of Genetic and Epigenetic Context to Predict the MGMT Methylation Status in Gliomas and Other Tumors
- (2016) Pierre Bady et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Research methods to change clinical practice for patients with rare cancers
- (2016) Lucinda Billingham et al. LANCET ONCOLOGY
- Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study
- (2016) Brigitta G Baumert et al. LANCET ONCOLOGY
- ABT-414, an Antibody-Drug Conjugate Targeting a Tumor-Selective EGFR Epitope
- (2016) A. C. Phillips et al. MOLECULAR CANCER THERAPEUTICS
- MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism
- (2016) Pratiti Bandopadhayay et al. NATURE GENETICS
- ATIM-03. ACT IV: AN INTERNATIONAL, DOUBLE-BLIND, PHASE 3 TRIAL OF RINDOPEPIMUT IN NEWLY DIAGNOSED, EGFRvIII-EXPRESSING GLIOBLASTOMA
- (2016) Michael Weller et al. NEURO-ONCOLOGY
- TTFields: where does all the skepticism come from?
- (2016) Wolfgang Wick NEURO-ONCOLOGY
- Complete resection of contrast-enhancing tumor volume is associated with improved survival in recurrent glioblastoma—results from the DIRECTOR trial
- (2016) Bogdana Suchorska et al. NEURO-ONCOLOGY
- Radiation plus Procarbazine, CCNU, and Vincristine in Low-Grade Glioma
- (2016) Jan C. Buckner et al. NEW ENGLAND JOURNAL OF MEDICINE
- Integrated multi-omics analysis of oligodendroglial tumours identifies three subgroups of 1p/19q co-deleted gliomas
- (2016) Aurélie Kamoun et al. Nature Communications
- CAR T Cells Targeting Podoplanin Reduce Orthotopic Glioblastomas in Mouse Brains
- (2016) S. Shiina et al. Cancer Immunology Research
- Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers
- (2015) Andrey Korshunov et al. ACTA NEUROPATHOLOGICA
- Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes
- (2015) David Castel et al. ACTA NEUROPATHOLOGICA
- Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets
- (2015) Felix Sahm et al. ACTA NEUROPATHOLOGICA
- Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups
- (2015) Michael Weller et al. ACTA NEUROPATHOLOGICA
- Glioblastoma: pathology, molecular mechanisms and markers
- (2015) Kenneth Aldape et al. ACTA NEUROPATHOLOGICA
- Gliomatosis cerebri: no evidence for a separate brain tumor entity
- (2015) Ulrich Herrlinger et al. ACTA NEUROPATHOLOGICA
- Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities
- (2015) David E. Reuss et al. ACTA NEUROPATHOLOGICA
- Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment
- (2015) Hinke F. van Thuijl et al. ACTA NEUROPATHOLOGICA
- Epithelioid Glioblastomas and Anaplastic Epithelioid Pleomorphic Xanthoastrocytomas-Same Entity or First Cousins?
- (2015) Sanda Alexandrescu et al. BRAIN PATHOLOGY
- Molecular Analysis of Pediatric Oligodendrogliomas Highlights Genetic Differences with Adult Counterparts and Other Pediatric Gliomas
- (2015) David Nauen et al. BRAIN PATHOLOGY
- MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin
- (2015) Marco Gallo et al. CANCER CELL
- DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors
- (2015) Tali Mazor et al. CANCER CELL
- Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups
- (2015) Kristian W. Pajtler et al. CANCER CELL
- Detection, Characterization, and Inhibition of FGFR-TACC Fusions in IDH Wild-type Glioma
- (2015) A. L. Di Stefano et al. CLINICAL CANCER RESEARCH
- MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial
- (2015) M. Weller et al. CLINICAL CANCER RESEARCH
- BRAF inhibitors in BRAF-V600 mutated primary neuroepithelial brain tumors
- (2015) Matthias Preusser et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Cancer stem cells in glioblastoma
- (2015) Justin D. Lathia et al. GENES & DEVELOPMENT
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- (2015) Roger Stupp et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
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- (2015) Nabil Ahmed et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2015) Naiyer A Rizvi et al. LANCET ONCOLOGY
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- (2015) C. Zahonero et al. MOLECULAR CANCER THERAPEUTICS
- EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling
- (2015) Feng Liu et al. MOLECULAR CELL
- Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients
- (2015) Duane A. Mitchell et al. NATURE
- Mutational landscape and clonal architecture in grade II and III gliomas
- (2015) Hiromichi Suzuki et al. NATURE GENETICS
- Integrated genomic characterization of IDH1-mutant glioma malignant progression
- (2015) Hanwen Bai et al. NATURE GENETICS
- Functionally defined therapeutic targets in diffuse intrinsic pontine glioma
- (2015) Catherine S Grasso et al. NATURE MEDICINE
- Prospects of immune checkpoint modulators in the treatment of glioblastoma
- (2015) Matthias Preusser et al. Nature Reviews Neurology
- Years of potential life lost for brain and CNS tumors relative to other cancers in adults in the United States, 2010
- (2015) Chaturia Rouse et al. NEURO-ONCOLOGY
- Molecular classification of anaplastic oligodendroglioma using next-generation sequencing: a report of the prospective randomized EORTC Brain Tumor Group 26951 phase III trial
- (2015) Hendrikus J. Dubbink et al. NEURO-ONCOLOGY
- Highlights from the Literature
- (2015) Wolfgang Wick et al. NEURO-ONCOLOGY
- A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: the ACT III study
- (2015) J. Schuster et al. NEURO-ONCOLOGY
- Immunosuppressive mechanisms in glioblastoma: Fig. 1.
- (2015) Edjah K. Nduom et al. NEURO-ONCOLOGY
- Toward precision medicine in glioblastoma: the promise and the challenges
- (2015) Michael D. Prados et al. NEURO-ONCOLOGY
- Targeted next-generation sequencing panel (GlioSeq) provides comprehensive genetic profiling of central nervous system tumors
- (2015) Marina N. Nikiforova et al. NEURO-ONCOLOGY
- CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012
- (2015) Quinn T. Ostrom et al. NEURO-ONCOLOGY
- Allelic loss of 9p21.3 is a prognostic factor in 1p/19q codeleted anaplastic gliomas
- (2015) Agustí Alentorn et al. NEUROLOGY
- Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas
- (2015) NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer
- (2015) Julie Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord
- (2015) Yuxuan Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Emerging roles of ATRX in cancer
- (2015) L Ashley Watson et al. Epigenomics
- TCF12 is mutated in anaplastic oligodendroglioma
- (2015) Karim Labreche et al. Nature Communications
- Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma
- (2015) Leticia De Mattos-Arruda et al. Nature Communications
- Exosomal levels of miRNA-21 from cerebrospinal fluids associated with poor prognosis and tumor recurrence of glioma patients
- (2015) Rui Shi et al. Oncotarget
- A differentially expressed set of microRNAs in cerebro-spinal fluid (CSF) can diagnose CNS malignancies
- (2015) Alessandra Drusco et al. Oncotarget
- Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model
- (2015) D. A. Reardon et al. Cancer Immunology Research
- Glioma
- (2015) Michael Weller et al. Nature Reviews Disease Primers
- Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma
- (2014) Benedikt Wiestler et al. ACTA NEUROPATHOLOGICA
- Mixed glioma with molecular features of composite oligodendroglioma and astrocytoma: a true “oligoastrocytoma”?
- (2014) Jason T. Huse et al. ACTA NEUROPATHOLOGICA
- Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma
- (2014) Felix Sahm et al. ACTA NEUROPATHOLOGICA
- Complete clinical regression of a BRAF V600E-mutant pediatric glioblastoma multiforme after BRAF inhibitor therapy
- (2014) Giles W Robinson et al. BMC CANCER
- International Society of Neuropathology-Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading
- (2014) David N. Louis et al. BRAIN PATHOLOGY
- Targeting Self-Renewal in High-Grade Brain Tumors Leads to Loss of Brain Tumor Stem Cells and Prolonged Survival
- (2014) Zhe Zhu et al. Cell Stem Cell
- Osteopontin-CD44 Signaling in the Glioma Perivascular Niche Enhances Cancer Stem Cell Phenotypes and Promotes Aggressive Tumor Growth
- (2014) Alexander Pietras et al. Cell Stem Cell
- Benefit From Procarbazine, Lomustine, and Vincristine in Oligodendroglial Tumors Is Associated With Mutation ofIDH
- (2014) J. Gregory Cairncross et al. JOURNAL OF CLINICAL ONCOLOGY
- Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial
- (2014) Roger Stupp et al. LANCET ONCOLOGY
- EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma
- (2014) Michael Weller et al. LANCET ONCOLOGY
- Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
- (2014) S. C. Mack et al. NATURE
- C11orf95–RELA fusions drive oncogenic NF-κB signalling in ependymoma
- (2014) Matthew Parker et al. NATURE
- A vaccine targeting mutant IDH1 induces antitumour immunity
- (2014) Theresa Schumacher et al. NATURE
- The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
- (2014) Gang Wu et al. NATURE GENETICS
- Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
- (2014) Pawel Buczkowicz et al. NATURE GENETICS
- Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma
- (2014) Rintaro Hashizume et al. NATURE MEDICINE
- MGMT testing—the challenges for biomarker-based glioma treatment
- (2014) Wolfgang Wick et al. Nature Reviews Neurology
- Immunotherapy advances for glioblastoma
- (2014) D. A. Reardon et al. NEURO-ONCOLOGY
- Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas
- (2014) M. A. Karajannis et al. NEURO-ONCOLOGY
- A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma
- (2014) Mark R. Gilbert et al. NEW ENGLAND JOURNAL OF MEDICINE
- Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma
- (2014) Olivier L. Chinot et al. NEW ENGLAND JOURNAL OF MEDICINE
- In vivo radiation response of proneural glioma characterized by protective p53 transcriptional program and proneural-mesenchymal shift
- (2014) J. Halliday et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
- (2014) A. P. Patel et al. SCIENCE
- Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia
- (2014) M. L. Davila et al. Science Translational Medicine
- Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies
- (2014) C. Bettegowda et al. Science Translational Medicine
- Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss
- (2013) Hideyuki Arita et al. ACTA NEUROPATHOLOGICA
- Epithelioid GBMs Show a High Percentage of BRAF V600E Mutation
- (2013) Bette Kay Kleinschmidt-DeMasters et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- BRAF-Mutated Pleomorphic Xanthoastrocytoma is Associated with Temporal Location, Reticulin Fiber Deposition and CD34 Expression
- (2013) Christian Koelsche et al. BRAIN PATHOLOGY
- Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas
- (2013) Sebastian Bender et al. CANCER CELL
- Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma
- (2013) Krishna P.L. Bhat et al. CANCER CELL
- The Somatic Genomic Landscape of Glioblastoma
- (2013) Cameron W. Brennan et al. CELL
- EGFRvIII mCAR-Modified T-Cell Therapy Cures Mice with Established Intracerebral Glioma and Generates Host Immunity against Tumor-Antigen Loss
- (2013) J. H. Sampson et al. CLINICAL CANCER RESEARCH
- MGMT-STP27 Methylation Status as Predictive Marker for Response to PCV in Anaplastic Oligodendrogliomas and Oligoastrocytomas. A Report from EORTC Study 26951
- (2013) M. J. van den Bent et al. CLINICAL CANCER RESEARCH
- Phase III Randomized Clinical Trial Comparing Tremelimumab With Standard-of-Care Chemotherapy in Patients With Advanced Melanoma
- (2013) Antoni Ribas et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase III Randomized Trial Comparing the Efficacy of Cediranib As Monotherapy, and in Combination With Lomustine, Versus Lomustine Alone in Patients With Recurrent Glioblastoma
- (2013) Tracy T. Batchelor et al. JOURNAL OF CLINICAL ONCOLOGY
- Dose-Dense Temozolomide for Newly Diagnosed Glioblastoma: A Randomized Phase III Clinical Trial
- (2013) Mark R. Gilbert et al. JOURNAL OF CLINICAL ONCOLOGY
- Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy
- (2013) Richard A. Morgan et al. JOURNAL OF IMMUNOTHERAPY
- Interlaboratory comparison of IDH mutation detection
- (2013) Martin J. van den Bent et al. JOURNAL OF NEURO-ONCOLOGY
- Salvage therapy with BRAF inhibitors for recurrent pleomorphic xanthoastrocytoma: a retrospective case series
- (2013) Marc C. Chamberlain JOURNAL OF NEURO-ONCOLOGY
- Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
- (2013) David T W Jones et al. NATURE GENETICS
- Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas
- (2013) NATURE GENETICS
- Implementing personalized cancer genomics in clinical trials
- (2013) Richard Simon et al. NATURE REVIEWS DRUG DISCOVERY
- Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation
- (2013) W. Wick et al. NEUROLOGY
- Nivolumab plus Ipilimumab in Advanced Melanoma
- (2013) Jedd D. Wolchok et al. NEW ENGLAND JOURNAL OF MEDICINE
- Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas
- (2013) A. J. Sievert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma
- (2013) P. W. Lewis et al. SCIENCE
- Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma
- (2013) B. E. Johnson et al. SCIENCE
- An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells
- (2013) D. Rohle et al. SCIENCE
- Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
- (2012) Dominik Sturm et al. CANCER CELL
- Optimal management of elderly patients with glioblastoma
- (2012) Normand Laperriere et al. CANCER TREATMENT REVIEWS
- Epidermal growth factor receptor
- (2012) Monika E. Hegi et al. CURRENT OPINION IN NEUROLOGY
- Phase III Trial of Chemoradiotherapy for Anaplastic Oligodendroglioma: Long-Term Results of RTOG 9402
- (2012) Gregory Cairncross et al. JOURNAL OF CLINICAL ONCOLOGY
- Adjuvant Procarbazine, Lomustine, and Vincristine Chemotherapy in Newly Diagnosed Anaplastic Oligodendroglioma: Long-Term Follow-Up of EORTC Brain Tumor Group Study 26951
- (2012) Martin J. van den Bent et al. JOURNAL OF CLINICAL ONCOLOGY
- Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): a multicentre, randomised, placebo-controlled phase 3 trial
- (2012) David Neal Franz et al. LANCET
- Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial
- (2012) Annika Malmström et al. LANCET ONCOLOGY
- Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial
- (2012) Wolfgang Wick et al. LANCET ONCOLOGY
- Phase 2 trial design in neuro-oncology revisited: a report from the RANO group
- (2012) Evanthia Galanis et al. LANCET ONCOLOGY
- Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
- (2012) Jeremy Schwartzentruber et al. NATURE
- IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
- (2012) Masato Sasaki et al. NATURE
- A restricted cell population propagates glioblastoma growth after chemotherapy
- (2012) Jian Chen et al. NATURE
- Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
- (2012) Gang Wu et al. NATURE GENETICS
- Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma
- (2012) D. Singh et al. SCIENCE
- Differential Sensitivity of Glioma- versus Lung Cancer–Specific EGFR Mutations to EGFR Kinase Inhibitors
- (2012) Igor Vivanco et al. Cancer Discovery
- Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma
- (2011) Genevieve Schindler et al. ACTA NEUROPATHOLOGICA
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- Mosaic Amplification of Multiple Receptor Tyrosine Kinase Genes in Glioblastoma
- (2011) Matija Snuderl et al. CANCER CELL
- BRAF-KIAA1549 Fusion Predicts Better Clinical Outcome in Pediatric Low-Grade Astrocytoma
- (2011) C. Hawkins et al. CLINICAL CANCER RESEARCH
- Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas
- (2011) Jörg Felsberg et al. INTERNATIONAL JOURNAL OF CANCER
- Validation of EORTC Prognostic Factors for Adults With Low-Grade Glioma: A Report Using Intergroup 86-72-51
- (2011) Thomas B. Daniels et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Intraoperative MRI guidance and extent of resection in glioma surgery: a randomised, controlled trial
- (2011) Christian Senft et al. LANCET ONCOLOGY
- Mutations in CIC and FUBP1 Contribute to Human Oligodendroglioma
- (2011) C. Bettegowda et al. SCIENCE
- Interobserver variation of the histopathological diagnosis in clinical trials on glioma: a clinician’s perspective
- (2010) Martin J. van den Bent ACTA NEUROPATHOLOGICA
- Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor
- (2010) B. Jena et al. BLOOD
- Loss of ATM/Chk2/p53 Pathway Components Accelerates Tumor Development and Contributes to Radiation Resistance in Gliomas
- (2010) Massimo Squatrito et al. CANCER CELL
- Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
- (2010) Houtan Noushmehr et al. CANCER CELL
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- Phase III Study of Enzastaurin Compared With Lomustine in the Treatment of Recurrent Intracranial Glioblastoma
- (2010) Wolfgang Wick et al. JOURNAL OF CLINICAL ONCOLOGY
- Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma
- (2010) John H. Sampson et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase II Trial of Continuous Dose-Intense Temozolomide in Recurrent Malignant Glioma: RESCUE Study
- (2010) James R. Perry et al. JOURNAL OF CLINICAL ONCOLOGY
- Distinct patterns of 1p and 19q alterations identify subtypes of human gliomas that have different prognoses†
- (2010) Artemis P. Vogazianou et al. NEURO-ONCOLOGY
- Everolimus for Subependymal Giant-Cell Astrocytomas in Tuberous Sclerosis
- (2010) Darcy A. Krueger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Monoclonal antibody specific for IDH1 R132H mutation
- (2009) David Capper et al. ACTA NEUROPATHOLOGICA
- Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma
- (2009) Henry S. Friedman et al. JOURNAL OF CLINICAL ONCOLOGY
- Randomized Phase II Trial of Erlotinib Versus Temozolomide or Carmustine in Recurrent Glioblastoma: EORTC Brain Tumor Group Study 26034
- (2009) Martin J. van den Bent et al. JOURNAL OF CLINICAL ONCOLOGY
- IDH1andIDH2Mutations in Gliomas
- (2009) Hai Yan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Analysis of the IDH1 codon 132 mutation in brain tumors
- (2008) Jörg Balss et al. ACTA NEUROPATHOLOGICA
- Ependymomas of the adult: molecular biology and treatment
- (2008) Roberta Rudà et al. CURRENT OPINION IN NEUROLOGY
- Phase II Trial of Single-Agent Bevacizumab Followed by Bevacizumab Plus Irinotecan at Tumor Progression in Recurrent Glioblastoma
- (2008) Teri N. Kreisl et al. JOURNAL OF CLINICAL ONCOLOGY
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- (2008) D. W. Parsons et al. SCIENCE
- Reirradiation Tolerance of the Human Brain
- (2007) Ramona Mayer et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
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