TheATG16L1–T300Aallele impairs clearance of pathosymbionts in the inflamed ileal mucosa of Crohn's disease patients

Eating for good health: Linking autophagy and phagocytosis in host defense

(2014) Miguel A. Sanjuan et al.   Autophagy

A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3

(2014) Aditya Murthy et al.   NATURE

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

(2014) K. G. Lassen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective Modulation of Autophagy, Innate Immunity, and Adaptive Immunity by Small Molecules

(2013) Stanley Y. Shaw et al.   ACS Chemical Biology

Glutathione and antioxidant enzymes serve complementary roles in protecting activated hepatic stellate cells against hydrogen peroxide-induced cell death

(2013) Sandra Dunning et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Diversity of human small intestinalStreptococcusandVeillonellapopulations

(2013) Bartholomeus van den Bogert et al.   FEMS MICROBIOLOGY ECOLOGY

Impact of Ileocecal Resection and Concomitant Antibiotics on the Microbiome of the Murine Jejunum and Colon

(2013) Anthony A. Devine et al.   PLoS One

Influence of the Protein Kinase C Activator Phorbol Myristate Acetate on the Intracellular Activity of Antibiotics against Hemin- and Menadione-Auxotrophic Small-Colony Variant Mutants of Staphylococcus aureus and Their Wild-Type Parental Strain in Human THP-1 Cells

(2012) Laetitia G. Garcia et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Crohn diseaseATG16L1polymorphism increases susceptibility to infection withHelicobacter pyloriin humans

(2012) Deepa Raju et al.   Autophagy

Defects in autophagy favour adherent-invasive Escherichia coli persistence within macrophages leading to increased pro-inflammatory response

(2012) Pierre Lapaquette et al.   CELLULAR MICROBIOLOGY

Fecal Microbiota Composition Differs Between Children With  -Cell Autoimmunity and Those Without

(2012) M. C. de Goffau et al.   DIABETES

Bacteria, Colonic Fermentation, and Gastrointestinal Health

(2012) George T. Macfarlane et al.   JOURNAL OF AOAC INTERNATIONAL

Prevention of postoperative recurrence of Crohn's disease

(2012) E.S. van Loo et al.   Journal of Crohns & Colitis

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

The impact of nutrition on the human microbiome

(2012) Harry J Flint   NUTRITION REVIEWS

Nod2 is essential for temporal development of intestinal microbial communities

(2011) A. Rehman et al.   GUT

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

Crohn's Disease Susceptibility Gene Interactions, a NOD to the Newcomer ATG16L1

(2010) Ken Cadwell   GASTROENTEROLOGY

Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases

(2010) Daniel N. Frank et al.   INFLAMMATORY BOWEL DISEASES

Highlighting new phylogenetic specificities of Crohnʼs disease microbiota

(2010) S. Mondot et al.   INFLAMMATORY BOWEL DISEASES

Rapidly denoising pyrosequencing amplicon reads by exploiting rank-abundance distributions

(2010) Jens Reeder et al.   NATURE METHODS

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Autophagy, Immunity, and Microbial Adaptations

(2009) Vojo Deretic et al.   Cell Host & Microbe

Crohn's disease-associated adherent-invasiveE. coliare selectively favoured by impaired autophagy to replicate intracellularly

(2009) Pierre Lapaquette et al.   CELLULAR MICROBIOLOGY

Comparative assessment of human and farm animal faecal microbiota using real-time quantitative PCR

(2009) Jean-Pierre Furet et al.   FEMS MICROBIOLOGY ECOLOGY

Differential Involvement of Atg16L1 in Crohn Disease and Canonical Autophagy

(2009) Naonobu Fujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microbial Influences in Inflammatory Bowel Diseases

(2008) R. Balfour Sartor   GASTROENTEROLOGY

Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohnʼs disease

(2008) Ben Willing et al.   INFLAMMATORY BOWEL DISEASES

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE

Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn's Disease Associated ATG16L1 Variant

(2008) Petric Kuballa et al.   PLoS One

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

(2008) H. Sokol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pervasive Effects of an Antibiotic on the Human Gut Microbiota, as Revealed by Deep 16S rRNA Sequencing

(2008) Les Dethlefsen et al.   PLOS BIOLOGY