HLA class II sequence variants influence tuberculosis risk in populations of European ancestry

Evaluating the Role of HLA-DM in MHC Class II–Peptide Association Reactions

(2015) Liusong Yin et al.   JOURNAL OF IMMUNOLOGY

Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration

(2015) James Curtis et al.   NATURE GENETICS

Large-scale whole-genome sequencing of the Icelandic population

(2015) Daniel F Gudbjartsson et al.   NATURE GENETICS

Ubiquitination by March-I prevents MHC class II recycling and promotes MHC class II turnover in antigen-presenting cells

(2015) Kyung-Jin Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Definition of CD4 Immunosignatures Associated with MTB

(2015) Cecilia S. Lindestam Arlehamn et al.   Frontiers in Immunology

Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA

(2014) Hiroko Miyadera et al.   JOURNAL OF CLINICAL INVESTIGATION

Tuberculin Skin Test Negativity Is Under Tight Genetic Control of Chromosomal Region 11p14-15 in Settings With Different Tuberculosis Endemicities

(2014) Aurélie Cobat et al.   JOURNAL OF INFECTIOUS DISEASES

Host genetic studies in adult pulmonary tuberculosis

(2014) Christian G. Meyer et al.   SEMINARS IN IMMUNOLOGY

Antigens for CD4 and CD8 T Cells in Tuberculosis

(2014) C. S. Lindestam Arlehamn et al.   Cold Spring Harbor Perspectives in Medicine

Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions

(2013) N. C. Sheffield et al.   GENOME RESEARCH

Genome-wide association study of ancestry-specific TB risk in the South African Coloured population

(2013) E. R. Chimusa et al.   HUMAN MOLECULAR GENETICS

Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits

(2013) Unnur Styrkarsdottir et al.   NATURE

On the perils of poor editing: regulation of peptide loading by HLA-DQ and H2-A molecules associated with celiac disease and type 1 diabetes

(2012) Robert Busch et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

(2012) J. Wang et al.   GENOME RESEARCH

Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules

(2012) Ludvig M. Sollid et al.   IMMUNOGENETICS

Heterozygous Carriage of a Dysfunctional Toll-like Receptor 9 Allele Affects CpG Oligonucleotide Responses in B Cells

(2012) Jelena Knežević et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Functional Studies oftrans-Encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) Protein Molecule

(2012) Stig Tollefsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dissecting Mechanisms of Immunodominance to the Common Tuberculosis Antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ)

(2012) C. S. Lindestam Arlehamn et al.   JOURNAL OF IMMUNOLOGY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Common variants at 11p13 are associated with susceptibility to tuberculosis

(2012) Thorsten Thye et al.   NATURE GENETICS

The NIH Roadmap Epigenomics Program data resource

(2012) Lisa Helbling Chadwick   Epigenomics

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

NCBI Reference Sequences (RefSeq): current status, new features and genome annotation policy

(2011) K. D. Pruitt et al.   NUCLEIC ACIDS RESEARCH

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

(2010) William McLaren et al.   BIOINFORMATICS

Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2

(2010) Thorsten Thye et al.   NATURE GENETICS

Toll-Like Receptor 2 (P631H) Mutant Impairs Membrane Internalization and is a Dominant Negative Allele

(2010) G. E. Etokebe et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++

(2010) Eugene V. Davydov et al.   PLoS Computational Biology

Identifying novel constrained elements by exploiting biased substitution patterns

(2009) Manuel Garber et al.   BIOINFORMATICS

Two loci control tuberculin skin test reactivity in an area hyperendemic for tuberculosis

(2009) Aurelie Cobat et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Impact of Divergence Time on the Nature of Population Structure: An Example from Iceland

(2009) Alkes L. Price et al.   PLoS Genetics

Active case finding of tuberculosis in Europe: a Tuberculosis Network European Trials Group (TBNET) survey

(2008) G. H. Bothamley et al.   EUROPEAN RESPIRATORY JOURNAL

Genetics of gene expression and its effect on disease

(2008) Valur Emilsson et al.   NATURE

Defining the Role of the MHC in Autoimmunity: A Review and Pooled Analysis

(2008) Michelle M. A. Fernando et al.   PLoS Genetics