Cis-regulatory architecture of a brain signaling center predates the origin of chordates

The conserved barH-like homeobox-2 gene barhl2 acts downstream of orthodentricle-2 and together with iroquois-3 in establishment of the caudal forebrain signaling center induced by Sonic Hedgehog

(2014) Hugo A. Juraver-Geslin et al.   DEVELOPMENTAL BIOLOGY

The Hippo Pathway Effector Yap Controls Patterning and Differentiation of Airway Epithelial Progenitors

(2014) John E. Mahoney et al.   DEVELOPMENTAL CELL

Functional and topological characteristics of mammalian regulatory domains

(2014) O. Symmons et al.   GENOME RESEARCH

A comparative encyclopedia of DNA elements in the mouse genome

(2014) Feng Yue et al.   NATURE

Quantitative genome-wide enhancer activity maps for five Drosophila species show functional enhancer conservation and turnover during cis-regulatory evolution

(2014) Cosmas D Arnold et al.   NATURE GENETICS

Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution

(2014) J. Vierstra et al.   SCIENCE

Massively parallel decoding of mammalian regulatory sequences supports a flexible organizational model

(2013) Robin P Smith et al.   NATURE GENETICS

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

A Transcription Factor Collective Defines Cardiac Cell Fate and Reflects Lineage History

(2012) Guillaume Junion et al.   CELL

β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

(2012) Joseph Rosenbluh et al.   CELL

(Re)inventing the Circadian Feedback Loop

(2012) Steven A. Brown et al.   DEVELOPMENTAL CELL

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

An expansive human regulatory lexicon encoded in transcription factor footprints

(2012) Shane Neph et al.   NATURE

Ancient deuterostome origins of vertebrate brain signalling centres

(2012) Ariel M. Pani et al.   NATURE

A map of the cis-regulatory sequences in the mouse genome

(2012) Yin Shen et al.   NATURE

Comparative genomics of the Hedgehog loci in chordates and the origins of Shh regulatory novelties

(2012) Manuel Irimia et al.   Scientific Reports

A Machine Learning Approach for Identifying Novel Cell Type–Specific Transcriptional Regulators of Myogenesis

(2012) Brian W. Busser et al.   PLoS Genetics

In-depth annotation of SNPs arising from resequencing projects using NGS-SNP

(2011) J. R. Grant et al.   BIOINFORMATICS

Involvement of Hedgehog and FGF signalling in the lamprey telencephalon: evolution of regionalization and dorsoventral patterning of the vertebrate forebrain

(2011) F. Sugahara et al.   DEVELOPMENT

Spatial and temporal requirements for sonic hedgehog in the regulation of thalamic interneuron identity

(2011) Y. Jeong et al.   DEVELOPMENT

Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor

(2011) Sandra Ruf et al.   NATURE GENETICS

Coordinated regulation of cholinergic motor neuron traits through a conserved terminal selector gene

(2011) Paschalis Kratsios et al.   NATURE NEUROSCIENCE

The same enhancer regulates the earliest Emx2 expression in caudal forebrain primordium, subsequent expression in dorsal telencephalon and later expression in the cortical ventricular zone

(2010) Y. Suda et al.   DEVELOPMENT

Otx2 and Otx1 protect diencephalon and mesencephalon from caudalization into metencephalon during early brain regionalization

(2010) Yusuke Sakurai et al.   DEVELOPMENTAL BIOLOGY

A unique chromatin signature uncovers early developmental enhancers in humans

(2010) Alvaro Rada-Iglesias et al.   NATURE

Building a bridal chamber: development of the thalamus

(2010) Steffen Scholpp et al.   TRENDS IN NEUROSCIENCES

Conserved developmental expression of Fezf in chordates and Drosophila and the origin of the Zona Limitans Intrathalamica (ZLI) brain organizer

(2010) Manuel Irimia et al.   EvoDevo

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation

(2009) A. Fernandez-L et al.   GENES & DEVELOPMENT

BARHL2 Differentially Regulates the Development of Retinal Amacrine and Ganglion Neurons

(2009) Q. Ding et al.   JOURNAL OF NEUROSCIENCE

Deep homology and the origins of evolutionary novelty

(2009) Neil Shubin et al.   NATURE

ChIP-seq accurately predicts tissue-specific activity of enhancers

(2009) Axel Visel et al.   NATURE

Combinatorial Regulation of Endothelial Gene Expression by Ets and Forkhead Transcription Factors

(2008) Sarah De Val et al.   CELL

The genetics of early telencephalon patterning: some assembly required

(2008) Jean M. Hébert et al.   NATURE REVIEWS NEUROSCIENCE

UniPROBE: an online database of protein binding microarray data on protein-DNA interactions

(2008) D. E. Newburger et al.   NUCLEIC ACIDS RESEARCH

Sepsid even-skipped Enhancers Are Functionally Conserved in Drosophila Despite Lack of Sequence Conservation

(2008) Emily E. Hare et al.   PLoS Genetics