Bestatin, A Pluripotent Immunomodulatory Small Molecule, Drives Robust and Long-Lasting Immune Responses as an Adjuvant in Viral Vaccines

Dectin-1 signaling coordinates innate and adaptive immunity for potent host defense against viral infection

(2023) Hyeong Won Kim et al.   Frontiers in Immunology

Characterization of Co-Stimulatory Ligand CD80/86 and Its Effect as a Molecular Adjuvant on DNA Vaccine Against Vibrio anguillarum in Flounder (Paralichthys olivaceus)

(2022) Wenjing Liu et al.   Frontiers in Immunology

The C3d-fused foot-and-mouth disease vaccine platform overcomes maternally-derived antibody interference by inducing a potent adaptive immunity

(2022) Min Ja Lee et al.   npj Vaccines

Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection

(2022) Sinu P. John et al.   Cell Reports

SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 immunogenicity in baboons and protection in mice

(2021) Jing-Hui Tian et al.   Nature Communications

Virus–Host Interactions in Foot-and-Mouth Disease Virus Infection

(2021) Kangli Li et al.   Frontiers in Immunology

Natural and Synthetic Saponins as Vaccine Adjuvants

(2021) Pengfei Wang   Vaccines

Modular complement assemblies for mitigating inflammatory conditions

(2021) Kelly M. Hainline et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revisiting the Coreceptor Function of Complement Receptor Type 2 (CR2, CD21); Coengagement With the B-Cell Receptor Inhibits the Activation, Proliferation, and Antibody Production of Human B Cells

(2021) Kristóf G. Kovács et al.   Frontiers in Immunology

The HSP70-fused foot-and-mouth disease epitope elicits cellular and humoral immunity and drives broad-spectrum protective efficacy

(2021) Hyundong Jo et al.   npj Vaccines

A Vaccine Strain of the A/ASIA/Sea-97 Lineage of Foot-and-Mouth Disease Virus with a Single Amino Acid Substitution in the P1 Region That Is Adapted to Suspension Culture Provides High Immunogenicity

(2021) Ji-Hyeon Hwang et al.   Vaccines

Ubenimex Suppresses the Ability of Migration and Invasion in Gastric Cancer Cells by Alleviating the Activity of the CD13/NAB1/MAPK Pathway

(2021) Xuehui Liu et al.   Cancer Management and Research

Epigallocatechin-3-Gallate as a Novel Vaccine Adjuvant

(2021) Yucheol Cheong et al.   Frontiers in Immunology

The Potential Adjuvanticity of CAvant®SOE for Foot-and-Mouth Disease Vaccine

(2021) Young-Hoon Ahn et al.   Vaccines

Interferon-Gamma Modulation of the Local T Cell Response to Alphavirus Encephalomyelitis

(2020) Victoria K. Baxter et al.   Viruses-Basel

A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking

(2020) Katherine J Susa et al.   eLife

Advanced Foot-And-Mouth Disease Vaccine Platform for Stimulation of Simultaneous Cellular and Humoral Immune Responses

(2020) Min Ja Lee et al.   Vaccines

Interferon-λ enhances adaptive mucosal immunity by boosting release of thymic stromal lymphopoietin

(2019) Liang Ye et al.   NATURE IMMUNOLOGY

Foot-and-mouth disease vaccines: recent updates and future perspectives

(2019) Mohamed Kamel et al.   ARCHIVES OF VIROLOGY

The role of cytokines in the regulation of NK cells in the tumor environment

(2019) Gordana M. Konjević et al.   CYTOKINE

Inhibition of LTA4H by bestatin in human and mouse colorectal cancer

(2019) Simin Zhao et al.   EBioMedicine

Insights into IL‐29: Emerging role in inflammatory autoimmune diseases

(2019) Jia‐Min Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mincle and STING-Stimulating Adjuvants Elicit Robust Cellular Immunity and Drive Long-Lasting Memory Responses in a Foot-and-Mouth Disease Vaccine

(2019) Min Ja Lee et al.   Frontiers in Immunology

What are the drugs of the future?

(2018) Huy X. Ngo et al.   MedChemComm

TLR4-based immunotherapeutics in cancer: a review of the achievements and shortcomings

(2018) Maryam A. Shetab Boushehri et al.   MOLECULAR PHARMACEUTICS

Pattern Recognition Receptors and the Host Cell Death Molecular Machinery

(2018) Gustavo P. Amarante-Mendes et al.   Frontiers in Immunology

Contribution of type III interferons to antiviral immunity: location, location, location

(2017) Sergei V. Kotenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition

(2017) Enfu Hui et al.   SCIENCE

Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity

(2017) Purnima Bhat et al.   Cell Death & Disease

The role of IL-29 in immunity and cancer

(2016) Noah E. Kelm et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Immune Cell Profiling of IFN-λ Response Shows pDCs Express Highest Level of IFN-λR1 and Are Directly Responsive via the JAK-STAT Pathway

(2016) Aoife Kelly et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Global Foot-and-Mouth Disease Research Update and Gap Analysis: 3 - Vaccines

(2016) L. Robinson et al.   Transboundary and Emerging Diseases

Discovery of Small Molecules for Fluorescent Detection of Complement Activation Product C3d

(2015) Ronald D. Gorham et al.   JOURNAL OF MEDICINAL CHEMISTRY

RIG-I in RNA virus recognition

(2015) Alison M. Kell et al.   VIROLOGY

C3d adjuvant effects are mediated through the activation of C3d-specific autoreactive T cells

(2014) Anne S De Groot et al.   IMMUNOLOGY AND CELL BIOLOGY

Ubenimex inhibits cell proliferation, migration and invasion in renal cell carcinoma: The effect is autophagy-associated

(2014) SHUAI LIU et al.   ONCOLOGY REPORTS

Unleashing the potential of NOD- and Toll-like agonists as vaccine adjuvants

(2014) C. Maisonneuve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fine tuning type I interferon responses

(2013) Paul J. Hertzog et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The Actin and Tetraspanin Networks Organize Receptor Nanoclusters to Regulate B Cell Receptor-Mediated Signaling

(2013) Pieta K. Mattila et al.   IMMUNITY

Type I interferon response and innate immune sensing of cancer

(2012) Mercedes B. Fuertes et al.   TRENDS IN IMMUNOLOGY

Marker vaccine potential of a foot-and-mouth disease virus with a partial VP1 G-H loop deletion

(2010) V.L. Fowler et al.   VACCINE

Modulation of human plasmacytoid DC function by IFN-λ1 (IL-29)

(2009) Nicholas J. Megjugorac et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Bestatin, an inhibitor for aminopeptidases, modulates the production of cytokines and chemokines by activated monocytes and macrophages

(2008) Battur Lkhagvaa et al.   CYTOKINE