ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity

Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway

(2016) PuiYee Chan et al.   Nature Chemical Biology

Differential regulation of the Hippo pathway by adherens junctions and apical–basal cell polarity modules

(2015) Chih-Chao Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mislocalization of the Cell Polarity Protein Scribble Promotes Mammary Tumorigenesis and Is Associated with Basal Breast Cancer

(2014) M. E. Feigin et al.   CANCER RESEARCH

Fas palmitoylation by the palmitoyl acyltransferase DHHC7 regulates Fas stability

(2014) A Rossin et al.   CELL DEATH AND DIFFERENTIATION

Scribble Modulates the MAPK/Fra1 Pathway to Disrupt Luminal and Ductal Integrity and Suppress Tumour Formation in the Mammary Gland

(2014) Nathan J. Godde et al.   PLoS Genetics

Insulin-Regulated Protein Palmitoylation Impacts Endothelial Cell Function

(2013) Xiaochao Wei et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Localization, Not Important in All Tumor-Suppressing Properties: A Lesson Learnt from Scribble

(2013) Imogen A. Elsum et al.   CELLS TISSUES ORGANS

Scribble regulates an EMT polarity pathway through modulation of MAPK-ERK signaling to mediate junction formation

(2013) I. A. Elsum et al.   JOURNAL OF CELL SCIENCE

2-Bromopalmitate Analogues as Activity-Based Probes To Explore Palmitoyl Acyltransferases

(2013) Baohui Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A genetic screen identifies an LKB1–MARK signalling axis controlling the Hippo–YAP pathway

(2013) Morvarid Mohseni et al.   NATURE CELL BIOLOGY

The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

(2013) Randy Johnson et al.   NATURE REVIEWS DRUG DISCOVERY

A new model and modulator of pulmonary oedema

(2012) Charlotte Harrison   NATURE REVIEWS DRUG DISCOVERY

Aberrant Overexpression of the Cell Polarity Module Scribble in Human Cancer

(2011) Valentina Vaira et al.   AMERICAN JOURNAL OF PATHOLOGY

The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells

(2011) Michelangelo Cordenonsi et al.   CELL

Exploring Protein Lipidation with Chemical Biology

(2011) Howard C. Hang et al.   CHEMICAL REVIEWS

Scribble-mediated membrane targeting of PHLPP1 is required for its negative regulation of Akt

(2011) Xin Li et al.   EMBO REPORTS

DHHC5 Protein Palmitoylates Flotillin-2 and Is Rapidly Degraded on Induction of Neuronal Differentiation in Cultured Cells

(2011) Yi Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia

(2011) Helen B. Pearson et al.   JOURNAL OF CLINICAL INVESTIGATION

Influence of whole arm loss of chromosome 16q on gene expression patterns in oestrogen receptor-positive, invasive breast cancer

(2011) Daniela Hungermann et al.   JOURNAL OF PATHOLOGY

DHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptors

(2011) Ali Pedram et al.   MOLECULAR BIOLOGY OF THE CELL

Global profiling of dynamic protein palmitoylation

(2011) Brent R Martin et al.   NATURE METHODS

The Palmitoylation Machinery Is a Spatially Organizing System for Peripheral Membrane Proteins

(2010) Oliver Rocks et al.   CELL

Small-molecule inhibition of APT1 affects Ras localization and signaling

(2010) Frank J Dekker et al.   Nature Chemical Biology

The chemical toolbox for monitoring protein fatty acylation and prenylation

(2010) Rami N Hannoush et al.   Nature Chemical Biology

Protein palmitoylation in neuronal development and synaptic plasticity

(2010) Yuko Fukata et al.   NATURE REVIEWS NEUROSCIENCE

Tandem fluorescence imaging of dynamic S-acylation and protein turnover

(2010) M. M. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteome Scale Characterization of HumanS-Acylated Proteins in Lipid Raft-enriched and Non-raft Membranes

(2009) Wei Yang et al.   MOLECULAR & CELLULAR PROTEOMICS

Large-scale profiling of protein palmitoylation in mammalian cells

(2009) Brent R Martin et al.   NATURE METHODS

Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma

(2008) Lixing Zhan et al.   CELL

Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation

(2008) Rujun Kang et al.   NATURE

Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling

(2008) L E Dow et al.   ONCOGENE