Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway

Palmitoylation of TEAD Transcription Factors Is Required for Their Stability and Function in Hippo Pathway Signaling

(2016) Cameron L. Noland et al.   STRUCTURE

Targeting Hippo pathway by specific interruption of YAP-TEAD interaction using cyclic YAP-like peptides

(2015) Zheng Zhou et al.   FASEB JOURNAL

Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy

(2015) Ajaybabu V. Pobbati et al.   STRUCTURE

Clickable Analogue of Cerulenin as Chemical Probe to Explore Protein Palmitoylation

(2014) Baohui Zheng et al.   ACS Chemical Biology

Novel TAZ modulators enhance myogenic differentiation and muscle regeneration

(2014) Gun Hwa Park et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer

(2014) Shi Jiao et al.   CANCER CELL

VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex

(2014) Wenjing Zhang et al.   CELL RESEARCH

Screening with a Novel Cell-Based Assay for TAZ Activators Identifies a Compound That Enhances Myogenesis in C2C12 Cells and Facilitates Muscle Repair in a Muscle Injury Model

(2014) Z. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

Metabolic control of YAP and TAZ by the mevalonate pathway

(2014) Giovanni Sorrentino et al.   NATURE CELL BIOLOGY

The Hippo Effector Yorkie Controls Normal Tissue Growth by Antagonizing Scalloped-Mediated Default Repression

(2013) Laura M. Koontz et al.   DEVELOPMENTAL CELL

2-Bromopalmitate Analogues as Activity-Based Probes To Explore Palmitoyl Acyltransferases

(2013) Baohui Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling

(2013) Gunther Zimmermann et al.   NATURE

The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

(2013) Randy Johnson et al.   NATURE REVIEWS DRUG DISCOVERY

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

DHHC ProteinS-Acyltransferases Use Similar Ping-Pong Kinetic Mechanisms but Display Different Acyl-CoA Specificities

(2012) Benjamin C. Jennings et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcription factor TEAD4 regulates expression of Myogenin and the unfolded protein response genes during C2C12 cell differentiation

(2011) A Benhaddou et al.   CELL DEATH AND DIFFERENTIATION

Exploring Protein Lipidation with Chemical Biology

(2011) Howard C. Hang et al.   CHEMICAL REVIEWS

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins

(2011) Anchal Chandra et al.   NATURE CELL BIOLOGY

Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

(2011) Shehab A Ismail et al.   Nature Chemical Biology

DHHC palmitoyl transferases: substrate interactions and (patho)physiology

(2011) Jennifer Greaves et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

Structural basis of YAP recognition by TEAD4 in the Hippo pathway

(2010) L. Chen et al.   GENES & DEVELOPMENT

Structural insights into the YAP and TEAD complex

(2010) Z. Li et al.   GENES & DEVELOPMENT

Palmitoylome profiling reveals S-palmitoylation–dependent antiviral activity of IFITM3

(2010) Jacob S Yount et al.   Nature Chemical Biology

Protein palmitoylation in neuronal development and synaptic plasticity

(2010) Yuko Fukata et al.   NATURE REVIEWS NEUROSCIENCE

Structural and functional analysis of the YAP-binding domain of human TEAD2

(2010) W. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Large-scale profiling of protein palmitoylation in mammalian cells

(2009) Brent R Martin et al.   NATURE METHODS

Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling

(2008) M. Ota et al.   DEVELOPMENT

The TEAD/TEF Family Protein Scalloped Mediates Transcriptional Output of the Hippo Growth-Regulatory Pathway

(2008) Shian Wu et al.   DEVELOPMENTAL CELL

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT