Acquisition of Drug Resistance and Dependence by Prions

The Extended Cell Panel Assay Characterizes the Relationship of Prion Strains RML, 79A, and 139A and Reveals Conversion of 139A to 79A-Like Prions in Cell Culture

(2012) A. M. Oelschlegel et al.   JOURNAL OF VIROLOGY

Strain-Specific Role of RNAs in Prion Replication

(2012) P. Saa et al.   JOURNAL OF VIROLOGY

Propagation of RML Prions in Mice Expressing PrP Devoid of GPI Anchor Leads to Formation of a Novel, Stable Prion Strain

(2012) Sukhvir Paul Mahal et al.   PLoS Pathogens

Prions on the move

(2011) Charles Weissmann et al.   EMBO REPORTS

Abrogation of Complex Glycosylation by Swainsonine Results in Strain- and Cell-specific Inhibition of Prion Replication

(2011) Shawn Browning et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prions

(2011) D. W. Colby et al.   Cold Spring Harbor Perspectives in Biology

The role of RNA in mammalian prion protein conversion

(2011) Mariana P. B. Gomes et al.   Wiley Interdisciplinary Reviews-RNA

Species-Dependent Differences in Cofactor Utilization for Formation of the Protease-Resistant Prion Protein in Vitro

(2010) Nathan R. Deleault et al.   BIOCHEMISTRY

Protein aggregation diseases: pathogenicity and therapeutic perspectives

(2010) Adriano Aguzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Transfer of a prion strain to different hosts leads to emergence of strain variants

(2010) S. P. Mahal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Darwinian Evolution of Prions in Cell Culture

(2010) J. Li et al.   SCIENCE

Generating a Prion with Bacterially Expressed Recombinant Prion Protein

(2010) F. Wang et al.   SCIENCE

A synergistic small-molecule combination directly eradicates diverse prion strain structures

(2009) Blake E Roberts et al.   Nature Chemical Biology

Continuous Quinacrine Treatment Results in the Formation of Drug-Resistant Prions

(2009) Sina Ghaemmaghami et al.   PLoS Pathogens

Role of Helix B Residues in Interfacial Activation of a Bacterial Phosphatidylinositol-Specific Phospholipase C†

(2008) Su Guo et al.   BIOCHEMISTRY