Artificial intelligence enabled ChatGPT and large language models in drug target discovery, drug discovery, and development

Large language models generate functional protein sequences across diverse families

(2023) Ali Madani et al.   NATURE BIOTECHNOLOGY

What artificial intelligence knows about 70 kDa heat shock proteins, and how we will face this ChatGPT era

(2023) Thiago Gomes Heck   CELL STRESS & CHAPERONES

Computational approaches streamlining drug discovery

(2023) Anastasiia V. Sadybekov et al.   NATURE

Drug discovery companies are customizing ChatGPT: here’s how

(2023) Neil Savage   NATURE BIOTECHNOLOGY

Large language models in medicine

(2023) Arun James Thirunavukarasu et al.   NATURE MEDICINE

Future implications of ChatGPT in pharmaceutical industry: drug discovery and development

(2023) Ailin Zhao et al.   Frontiers in Pharmacology

AI in small-molecule drug discovery: a coming wave?

(2022) Madura K.P. Jayatunga et al.   NATURE REVIEWS DRUG DISCOVERY

Emerging frontiers in virtual drug discovery: From quantum mechanical methods to deep learning approaches

(2022) Christoph Gorgulla et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The Drug Repurposing for COVID-19 Clinical Trials Provide Very Effective Therapeutic Combinations: Lessons Learned From Major Clinical Studies

(2021) Chiranjib Chakraborty et al.   Frontiers in Pharmacology

Functional Genomics for Cancer Drug Target Discovery

(2020) Benjamin Haley et al.   CANCER CELL

Repurposing Drugs, Ongoing Vaccine, and New Therapeutic Development Initiatives Against COVID-19

(2020) Rudra P. Saha et al.   Frontiers in Pharmacology

An omics perspective on drug target discovery platforms

(2019) Jussi Paananen et al.   BRIEFINGS IN BIOINFORMATICS

Evaluating Protein-protein Interaction (PPI) Networks for Diseases Pathway, Target Discovery, and Drug-design Using ‘In silico Pharmacology’

(2014) Chiranjib Chakraborty et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Targeting Catechol-O-Methyl Transferase (COMT) Inhibitors for Schizophrenia:An Approach to Target Validation and Rational Drug Design

(2011) Deepak Purushotham et al.   Letters in Drug Design & Discovery

Network Building of Proteins in a Biochemical Pathway: A Computational Biology Related Model for Target Discovery and Drug-Design

(2010) Chiranjib Chakraborty et al.   Current Bioinformatics