Comprehensive Search for GPCR Compounds which Can Enhance MafA and/or PDX-1 Expression Levels Using a Small Molecule Compound Library
出版年份 2023 全文链接
标题
Comprehensive Search for GPCR Compounds which Can Enhance MafA and/or PDX-1 Expression Levels Using a Small Molecule Compound Library
作者
关键词
-
出版物
Journal of Diabetes Research
Volume 2023, Issue -, Pages 1-8
出版商
Hindawi Limited
发表日期
2023-09-08
DOI
10.1155/2023/8803172
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- GPCR systems pharmacology: a different perspective on the development of biased therapeutics
- (2022) Dylan Scott Eiger et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Translating the force—mechano-sensing GPCRs
- (2022) Caroline Wilde et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- G protein-coupled receptors as regulators of pancreatic islet functionality
- (2022) Doreen Thor BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Molecular Mechanism of Pancreatic β-Cell Failure in Type 2 Diabetes Mellitus
- (2022) Hideaki Kaneto et al. Biomedicines
- Cell Cycle Regulation of the Pdx1 Transcription Factor in Developing Pancreas and Insulin-Producing β Cells
- (2021) Xiaogdong Zhu et al. DIABETES
- PDX1LOW MAFALOW β-cells contribute to islet function and insulin release
- (2021) Daniela Nasteska et al. Nature Communications
- Glucolipotoxicity and GLP-1 secretion
- (2021) Jung-Hee Hong et al. BMJ Open Diabetes Research & Care
- Early combination therapy of empagliflozin and linagliptin exerts beneficial effects on pancreatic β cells in diabetic db/db mice
- (2021) Yoshiro Fushimi et al. Scientific Reports
- MafA, NeuroD1, and HNF1β synergistically activate the Slc2a2 (Glut2) gene in β-cells
- (2021) Yuka Ono et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- The β-cell glucose toxicity hypothesis: Attractive but difficult to prove
- (2021) Gordon C. Weir et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Transcription factors that shape the mammalian pancreas
- (2020) Rachel E. Jennings et al. DIABETOLOGIA
- Notable Underlying Mechanism for Pancreatic β-Cell Dysfunction and Atherosclerosis: Pleiotropic Roles of Incretin and Insulin Signaling
- (2020) Hideaki Kaneto et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Vascular endothelial PDPK1 plays a pivotal role in the maintenance of pancreatic beta cell mass and function in adult male mice
- (2019) Atsushi Obata et al. DIABETOLOGIA
- Loss of MafA and MafB expression promotes islet inflammation
- (2019) Tania Singh et al. Scientific Reports
- Glucolipotoxicity Alters Insulin Secretion via Epigenetic Changes in Human Islets
- (2019) Elin Hall et al. DIABETES
- Recent Insights Into Mechanisms of β-Cell Lipo- and Glucolipotoxicity in Type 2 Diabetes
- (2019) Maria Lytrivi et al. JOURNAL OF MOLECULAR BIOLOGY
- Protective effects of the SGLT2 inhibitor luseogliflozin on pancreatic β-cells in db/db mice: The earlier and longer, the better
- (2018) Tomohiko Kimura et al. DIABETES OBESITY & METABOLISM
- Pancreatic β-Cell Rest Replenishes Insulin Secretory Capacity and Attenuates Diabetes in an Extreme Model of Obese Type 2 Diabetes
- (2018) Brandon B. Boland et al. DIABETES
- PDX1, Neurogenin-3, and MAFA: critical transcription regulators for beta cell development and regeneration
- (2017) Yaxi Zhu et al. Stem Cell Research & Therapy
- Development of novel ligands for peptide GPCRs
- (2016) Brian M Moran et al. CURRENT OPINION IN PHARMACOLOGY
- Impact of Pdx1-associated chromatin modifiers on islet β-cells
- (2016) J. M. Spaeth et al. DIABETES OBESITY & METABOLISM
- Glucose and GTP-binding protein-coupled receptor cooperatively regulate transient receptor potential-channels to stimulate insulin secretion [Review]
- (2016) Masafumi Kakei et al. ENDOCRINE JOURNAL
- Pancreatic β-Cell Adaptive Plasticity in Obesity Increases Insulin Production but Adversely Affects Secretory Function
- (2015) Cristina Alarcon et al. DIABETES
- Preserving Mafa Expression in Diabetic Islet β-Cells Improves Glycemic Controlin Vivo
- (2015) Taka-aki Matsuoka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protective effects of pioglitazone and/or liraglutide on pancreatic β-cells in db/db mice: Comparison of their effects between in an early and advanced stage of diabetes
- (2015) Tomohiko Kimura et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Appropriate therapy for type 2 diabetes mellitus in view of pancreatic β-cell glucose toxicity: “the earlier, the better”
- (2015) Hideaki Kaneto et al. Journal of Diabetes
- β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment
- (2014) Philippe A. Halban et al. DIABETES CARE
- Free Fatty Acids-Sensing G Protein-Coupled Receptors in Drug Targeting and Therapeutics
- (2013) Tomo Yonezawa et al. CURRENT MEDICINAL CHEMISTRY
- A Novel Function of Onecut1 Protein as a Negative Regulator ofMafAGene Expression
- (2013) Kaoru Yamamoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes
- (2011) M. Shimoda et al. DIABETOLOGIA
- Regulation of MafA Expression in Pancreatic -Cells in db/db Mice With Diabetes
- (2010) T.-a. Matsuoka et al. DIABETES
- The Year In G Protein-Coupled Receptor Research
- (2009) Robert P. Millar et al. MOLECULAR ENDOCRINOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now