Nanodrug formulations to enhance HIV drug exposure in lymphoid tissues and cells: clinical significance and potential impact on treatment and eradication of HIV/AIDS

Anti-HIV Drug-Combination Nanoparticles Enhance Plasma Drug Exposure Duration as Well as Triple-Drug Combination Levels in Cells Within Lymph Nodes and Blood in Primates

(2015) Jennifer P. Freeling et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

HIV Replication at Low Copy Number and its Correlation with the HIV Reservoir: A Clinical Perspective

(2015) Loredana Sarmati et al.   CURRENT HIV RESEARCH

Anatomical, Physiological, and Experimental Factors Affecting the Bioavailability of sc-Administered Large Biotherapeutics

(2015) Anas M. Fathallah et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Long-acting three-drug combination anti-HIV nanoparticles enhance drug exposure in primate plasma and cells within lymph nodes and blood

(2014) Jennifer P. Freeling et al.   AIDS

Development of HIV Reservoir Targeted Long Acting Nanoformulated Antiretroviral Therapies

(2014) Benson Edagwa et al.   CURRENT MEDICINAL CHEMISTRY

Antiretroviral Treatment of Adult HIV Infection

(2014) Huldrych F. Günthard et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Nano-chemotherapeutics: Maximising lymphatic drug exposure to improve the treatment of lymph-metastatic cancers

(2014) Gemma M. Ryan et al.   JOURNAL OF CONTROLLED RELEASE

Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

(2014) Courtney V. Fletcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-HIV drug particles may overcome lymphatic drug insufficiency and associated HIV persistence

(2014) J. P. Freeling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Towards nanomedicines for neuroAIDS

(2014) Vidya Sagar et al.   REVIEWS IN MEDICAL VIROLOGY

Current Perspectives on HIV-1 Antiretroviral Drug Resistance

(2014) Pinar Iyidogan et al.   Viruses-Basel

Enhanced Oral Bioavailability of Efavirenz by Solid Lipid Nanoparticles:In VitroDrug Release and Pharmacokinetics Studies

(2014) Praveen Kumar Gaur et al.   Biomed Research International

Preclinical Pharmacokinetics and Tissue Distribution of Long-Acting Nanoformulated Antiretroviral Therapy

(2013) Nagsen Gautam et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A review of nanotechnological approaches for the prophylaxis of HIV/AIDS

(2013) Abhijit A. Date et al.   BIOMATERIALS

Formulation and transport properties of tenofovir loaded liposomes through Caco-2 cell model

(2013) Ahmed S. Zidan et al.   JOURNAL OF LIPOSOME RESEARCH

Long-acting parenteral nanoformulated antiretroviral therapy: interest and attitudes of HIV-infected patients

(2013) Jennifer Williams et al.   Nanomedicine

Design and Characterization of Novel Peptide-Coated Lipid Nanoparticles for Targeting Anti-HIV Drug to CD4 Expressing Cells

(2012) Aaron N. Endsley et al.   AAPS Journal

Mechanistic Determinants of Biotherapeutics Absorption Following SC Administration

(2012) Wolfgang F. Richter et al.   AAPS Journal

Investigation on the stability of saquinavir loaded liposomes: Implication on stealth, release characteristics and cytotoxicity

(2012) Lakshmi Narashimhan Ramana et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Carbosilane dendrimer nanotechnology outlines of the broad HIV blocker profile

(2012) L. Chonco et al.   JOURNAL OF CONTROLLED RELEASE

Submicron-size biodegradable polymer-based didanosine particles for treating HIV at early stage: anin vitrostudy

(2012) Gurudutta Pattnaik et al.   JOURNAL OF MICROENCAPSULATION

Nanoencapsulation and Characterization of Zidovudine on Poly(L-lactide) and Poly(L-lactide)—Poly(ethylene glycol)-Blend Nanoparticles

(2012) Rubiana Mara Mainardes et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Intranasal administration of antiretroviral-loaded micelles for anatomical targeting to the brain in HIV

(2012) Diego A Chiappetta et al.   Nanomedicine

Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

(2012) Vikash P. Chauhan et al.   Nature Nanotechnology

Developing strategies for HIV-1 eradication

(2012) Christine M. Durand et al.   TRENDS IN IMMUNOLOGY

Electrospun cellulose acetate phthalate fibers for semen induced anti-HIV vaginal drug delivery

(2011) Chaobo Huang et al.   BIOMATERIALS

Expression of ornithine decarboxylase during the transport of saquinavir across the blood–brain barrier using composite polymeric nanocarriers under an electromagnetic field

(2011) Yung-Chih Kuo et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Current understanding of HIV-associated neurocognitive disorders pathogenesis

(2011) Patrick Gannon et al.   CURRENT OPINION IN NEUROLOGY

pH-responsive nanoparticles releasing tenofovir intended for the prevention of HIV transmission

(2011) Tao Zhang et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Targeting nevirapine delivery across human brain microvascular endothelial cells using transferrin-grafted poly(lactide-co-glycolide) nanoparticles

(2011) Yung-Chih Kuo et al.   Nanomedicine

Lymph nodes harbor viral reservoirs that cause rebound of plasma viremia in SIV-infected macaques upon cessation of combined antiretroviral therapy

(2011) Mariko Horiike et al.   VIROLOGY

Near-Infrared Investigations of Novel Anti-HIV Tenofovir Liposomes

(2010) Ahmed S. Zidan et al.   AAPS Journal

Evidence for the cure of HIV infection by CCR5 32/ 32 stem cell transplantation

(2010) K. Allers et al.   BLOOD

Physicochemical properties of nevirapine-loaded solid lipid nanoparticles and nanostructured lipid carriers

(2010) Yung-Chih Kuo et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Potential of polymeric nanoparticles in AIDS treatment and prevention

(2010) Najeh Maissar Khalil et al.   Expert Opinion on Drug Delivery

Emerging nanotechnology approaches for HIV/AIDS treatment and prevention

(2010) Tewodros Mamo et al.   Nanomedicine

Assessment of efficacy and tolerability of once-daily extended release metformin in patients with type 2 diabetes mellitus

(2010) Juliana Levy et al.   Diabetology & Metabolic Syndrome

HIV, Antiretroviral Therapies, and the Brain

(2010) Kevin J. Liner et al.   Current HIV/AIDS Reports

The transport of anti-HIV drugs across blood–CNS interfaces: Summary of current knowledge and recommendations for further research

(2009) Lavanya Varatharajan et al.   ANTIVIRAL RESEARCH

The development of antiretroviral therapy and its impact on the HIV-1/AIDS pandemic

(2009) Samuel Broder   ANTIVIRAL RESEARCH

Clinical experience with Flebogamma®5% DIF: a new generation of intravenous immunoglobulins in patients with primary immunodeficiency disease

(2009) M. Ballow   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

NanoART, neuroAIDS and CNS drug delivery

(2009) Ari Nowacek et al.   Nanomedicine

Radiolabeling, pharmacoscintigraphic evaluation and antiretroviral efficacy of stavudine loaded 99mTc labeled galactosylated liposomes

(2008) Minakshi Garg et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Pharmacokinetics and Biodistribution of Nanoparticles

(2008) Shyh-Dar Li et al.   MOLECULAR PHARMACEUTICS

HIV rebounds from latently infected cells, rather than from continuing low-level replication

(2008) B. Joos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

(2008) B. F. Keele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PEGylated Elastic Liposomal Formulation for Lymphatic Targeting of Zidovudine

(2008) Subheet Jain et al.   Current Drug Delivery

Improved oral bioavailability and brain transport of Saquinavir upon administration in novel nanoemulsion formulations

(2007) Tushar K. Vyas et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS