Single-cell RNA sequencing distinctly characterizes the wide heterogeneity in pediatric mixed phenotype acute leukemia

Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia

(2023) Hope Mumme et al.   Nature Communications

LMO2 expression is frequent in T-lymphoblastic leukemia and correlates with survival, regardless of T-cell stage

(2022) Kerri-Ann Latchmansingh et al.   MODERN PATHOLOGY

The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms

(2022) Joseph D. Khoury et al.   LEUKEMIA

Single-cell analysis reveals the chemotherapy-induced cellular reprogramming and novel therapeutic targets in relapsed/refractory acute myeloid leukemia

(2022) Kening Li et al.   LEUKEMIA

U2af1 is required for survival and function of hematopoietic stem/progenitor cells

(2021) Avik Dutta et al.   LEUKEMIA

Mapping the immune environment in clear cell renal carcinoma by single-cell genomics

(2021) Nicholas Borcherding et al.   Communications Biology

Mixed Phenotype Acute Leukemia: Current Approaches to Diagnosis and Treatment

(2021) Thomas B. Alexander et al.   Current Oncology Reports

Inference and analysis of cell-cell communication using CellChat

(2021) Suoqin Jin et al.   Nature Communications

Integrated analysis of multimodal single-cell data

(2021) Yuhan Hao et al.   CELL

Redefining the biological basis of lineage-ambiguous leukemia through genomics: BCL11B deregulation in acute leukemias of ambiguous lineage

(2021) Lindsey E. Montefiori et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Pediatric Single Cell Cancer Atlas: An Integrative Web-Based Resource for Single Cell Transcriptome Data from Pediatric Leukemias

(2021) Hope L Mumme et al.   BLOOD

STMN1 is highly expressed and contributes to clonogenicity in acute promyelocytic leukemia cells

(2021) Hugo Passos Vicari et al.   INVESTIGATIONAL NEW DRUGS

Significance of minimal residual disease in pediatric mixed phenotype acute leukemia: a multicenter cohort study

(2020) Matthew J. Oberley et al.   LEUKEMIA

Tetraspanin CD82 drives acute myeloid leukemia chemoresistance by modulating protein kinase C alpha and β1 integrin activation

(2020) Muskan Floren et al.   ONCOGENE

Single-cell analysis of childhood leukemia reveals a link between developmental states and ribosomal protein expression as a source of intra-individual heterogeneity

(2020) Maxime Caron et al.   Scientific Reports

Risk associated alterations in marrow T cells in pediatric leukemia

(2020) Jithendra Kini Bailur et al.   JCI Insight

Prognostic implications of the expression levels of different immunoglobulin heavy chain-encoding RNAs in early breast cancer

(2020) Christer Larsson et al.   npj Breast Cancer

CD81 knockout promotes chemosensitivity and disrupts in vivo homing and engraftment in acute lymphoblastic leukemia

(2020) Anthony Quagliano et al.   Blood Advances

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

(2019) Dvir Aran et al.   NATURE IMMUNOLOGY

Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity

(2019) Peter van Galen et al.   CELL

Single‑cell intratumoral stemness analysis reveals the involvement of cell cycle and DNA damage repair in two different types of esophageal cancer

(2019) Hongjin Wu et al.   ONCOLOGY REPORTS

T-lymphoid/myeloid mixed phenotype acute leukemia and early T-cell precursor lymphoblastic leukemia similarities with NOTCH1 mutation as a good prognostic factor

(2019) Elda Pereira Noronha et al.   Cancer Management and Research

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL

(2019) Salma Parvin et al.   CANCER CELL

SOX4: The unappreciated oncogene

(2019) Carlos S. Moreno   SEMINARS IN CANCER BIOLOGY

Fast, sensitive and accurate integration of single-cell data with Harmony

(2019) Ilya Korsunsky et al.   NATURE METHODS

MT2A is an early predictive biomarker of response to chemotherapy and a potential therapeutic target in osteosarcoma

(2019) Adèle Mangelinck et al.   Scientific Reports

Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia

(2019) Jeffrey M. Granja et al.   NATURE BIOTECHNOLOGY

International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia

(2018) Ondrej Hrusak et al.   BLOOD

Role of CD81 and CD58 in minimal residual disease detection in pediatric B lymphoblastic leukemia

(2018) E. Tsitsikov et al.   International Journal of Laboratory Hematology

Therapy for children and adults with mixed phenotype acute leukemia: a systematic review and meta-analysis

(2018) Maria Maruffi et al.   LEUKEMIA

Integrative genomic analysis of adult mixed phenotype acute leukemia delineates lineage associated molecular subtypes

(2018) Koichi Takahashi et al.   Nature Communications

The genetic basis and cell of origin of mixed phenotype acute leukaemia

(2018) Thomas B. Alexander et al.   NATURE

Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias

(2018) Shahzya Chaudhury et al.   Nature Communications

Single-cell transcriptomics to explore the immune system in health and disease

(2017) Michael J. T. Stubbington et al.   SCIENCE

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

The Human Cell Atlas

(2017) Aviv Regev et al.   eLife

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

(2016) D. A. Arber et al.   BLOOD

Whole-exome sequencing reveals the spectrum of gene mutations and the clonal evolution patterns in paediatric acute myeloid leukaemia

(2016) Norio Shiba et al.   BRITISH JOURNAL OF HAEMATOLOGY

MSC surface markers (CD44, CD73, and CD90) can identify human MSC-derived extracellular vesicles by conventional flow cytometry

(2016) Teresa L. Ramos et al.   Cell Communication and Signaling

Tetraspanin CD81 is an adverse prognostic marker in acute myeloid leukemia

(2016) Thomas Boyer et al.   Oncotarget

The role of CD44 in fetal and adult hematopoietic stem cell regulation

(2015) H. Cao et al.   HAEMATOLOGICA

The role of CD44 in fetal and adult hematopoietic stem cell regulation

(2015) H. Cao et al.   HAEMATOLOGICA

An expression atlas of human primary cells: inference of gene function from coexpression networks

(2013) Neil A Mabbott et al.   BMC GENOMICS

SOX4 enables oncogenic survival signals in acute lymphoblastic leukemia

(2012) P. Ramezani-Rad et al.   BLOOD

The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia

(2012) L. Zuurbier et al.   HAEMATOLOGICA

A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancers

(2012) Nathan P Palmer et al.   GENOME BIOLOGY

Interferon-α in acute myeloid leukemia: an old drug revisited

(2011) S Anguille et al.   LEUKEMIA

The role of FKBP5 in cancer aetiology and chemoresistance

(2010) L Li et al.   BRITISH JOURNAL OF CANCER

Targeting the heparin-binding epidermal growth factor-like growth factor in ovarian cancer therapy

(2010) Hiroshi Tsujioka et al.   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

Aberrant Underexpression of CD81 in Precursor B-Cell Acute Lymphoblastic Leukemia

(2009) Tariq Muzzafar et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY