Microfabrication and lab-on-a-chip devices promote in vitro modeling of neural interfaces for neuroscience researches and preclinical applications

Lab-on-Chip Microsystems for Ex Vivo Network of Neurons Studies: A Review

(2022) Hongyong Zhang et al.   Frontiers in Bioengineering and Biotechnology

Microfluidic platforms for single neuron analysis

(2022) Pallavi Gupta et al.   Materials Today Bio

In-situ monitoring calcium signaling through tumor microtubes for single cell-cell communication via an open microfluidic probe

(2022) Shuo Feng et al.   BIOSENSORS & BIOELECTRONICS

Microelectrode array membranes to simultaneously assess cardiac and neurological signals of xenopus laevis under chemical exposures and environmental changes

(2022) Xing Xia et al.   BIOSENSORS & BIOELECTRONICS

Microfluidics for understanding model organisms

(2022) Nolan Frey et al.   Nature Communications

A review on microelectrode array fabrication techniques and their applications

(2022) A. Tanwar et al.   Materials Today Chemistry

Electrophysiological Analysis of Brain Organoids: Current Approaches and Advancements

(2021) Austin P. Passaro et al.   Frontiers in Neuroscience

Aligned microfiber-induced macrophage polarization to guide schwann-cell-enabled peripheral nerve regeneration

(2021) Xianhao Dong et al.   BIOMATERIALS

Challenges of fused deposition modeling 3D printing in pharmaceutical applications: Where are we now?

(2021) Chloé Parulski et al.   ADVANCED DRUG DELIVERY REVIEWS

Microphysiological models of the central nervous system with fluid flow

(2021) Aleeza Zilberman et al.   BRAIN RESEARCH BULLETIN

In Vitro Electrochemical Detection of Hydrogen Peroxide in Activated Macrophages via a Platinum Microelectrode Array

(2021) Victor M. Carriere et al.   SENSORS

Morphine-sensitive synaptic transmission emerges in embryonic rat microphysiological model of lower afferent nociceptive signaling

(2021) Kevin J. Pollard et al.   Science Advances

A 3D flexible neural interface based on a microfluidic interconnection cable capable of chemical delivery

(2021) Yoo Na Kang et al.   Microsystems & Nanoengineering

Micropatterns and peptide gradient on the inner surface of a guidance conduit synergistically promotes nerve regeneration in vivo

(2021) Deteng Zhang et al.   Bioactive Materials

Closed-Loop Neural Prostheses With On-Chip Intelligence: A Review and a Low-Latency Machine Learning Model for Brain State Detection

(2021) Bingzhao Zhu et al.   IEEE Transactions on Biomedical Circuits and Systems

Human neural tube morphogenesis in vitro by geometric constraints

(2021) Eyal Karzbrun et al.   NATURE

Construction and imaging of a neurovascular unit model

(2021) Taiwei Dong et al.   Neural Regeneration Research

Spatial transcriptomics reveals a role for sensory nerves in preserving cranial suture patency through modulation of BMP/TGF-β signaling

(2021) Robert J. Tower et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

(2020) Pedro Rifes et al.   NATURE BIOTECHNOLOGY

Polycarbonate Heat Molding for Soft Lithography

(2020) Utku M. Sonmez et al.   Small

Application of Fused Organoid Models to Study Human Brain Development and Neural Disorders

(2020) Augustin Chen et al.   Frontiers in Cellular Neuroscience

Rapid prototyping of multilayer microphysiological systems

(2020) Sanjin Hosic et al.   ACS Biomaterials-Science & Engineering

3D‐Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices

(2020) Janko Kajtez et al.   Advanced Science

A glycolytic shift in Schwann cells supports injured axons

(2020) Elisabetta Babetto et al.   NATURE NEUROSCIENCE

Creation of bladder assembloids mimicking tissue regeneration and cancer

(2020) Eunjee Kim et al.   NATURE

Fabrication and Characterization of 3D Printed, 3D Microelectrode Arrays for Interfacing with a Peripheral Nerve-on-a-Chip

(2020) Avra Kundu et al.   ACS Biomaterials-Science & Engineering

Cerebral organoids at the air–liquid interface generate diverse nerve tracts with functional output

(2019) Stefano L. Giandomenico et al.   NATURE NEUROSCIENCE

Flow-enhanced vascularization and maturation of kidney organoids in vitro

(2019) Kimberly A. Homan et al.   NATURE METHODS

A bioprinted human-glioblastoma-on-a-chip for the identification of patient-specific responses to chemoradiotherapy

(2019) Hee-Gyeong Yi et al.   Nature Biomedical Engineering

High-throughput microfluidic characterization of erythrocyte shapes and mechanical variability

(2019) Felix Reichel et al.   BIOPHYSICAL JOURNAL

Optogenetic neuronal stimulation promotes axon outgrowth and myelination of motor neurons in a three‐dimensional motor neuron–Schwann cell coculture model on a microfluidic biochip

(2019) Sujin Hyung et al.   BIOTECHNOLOGY AND BIOENGINEERING

Microfluidic Brain-on-a-Chip: Perspectives for Mimicking Neural System Disorders

(2019) Mirza Ali Mofazzal Jahromi et al.   MOLECULAR NEUROBIOLOGY

Organoids-on-a-chip

(2019) Sunghee Estelle Park et al.   SCIENCE

Engineering a 3D functional human peripheral nerve in vitro using the Nerve-on-a-Chip platform

(2019) Anup D. Sharma et al.   Scientific Reports

Long-Term Developmental Process of the Human Cortex Revealed In Vitro by Axon-Targeted Recording Using a Microtunnel-Augmented Microelectrode Array

(2019) Kenta Shimba et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

A Critical Review of Microelectrode Arrays and Strategies for Improving Neural Interfaces

(2019) Morgan Ferguson et al.   Advanced Healthcare Materials

In vitro and in vivo biocompatibility evaluation of a 3D bioprinted gelatin-sodium alginate/rat Schwann-cell scaffold

(2019) Zongxi Wu et al.   Materials Science & Engineering C-Materials for Biological Applications

Advances in ex vivo models and lab-on-a-chip devices for neural tissue engineering

(2018) Sahba Mobini et al.   BIOMATERIALS

Neural Stem Cell Differentiation Using Microfluidic Device-Generated Growth Factor Gradient

(2018) Ji Hyeon Kim et al.   Biomolecules & Therapeutics

Bioprinting and its applications in tissue engineering and regenerative medicine

(2018) Waeljumah Aljohani et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

An in vivo model of functional and vascularized human brain organoids

(2018) Abed AlFatah Mansour et al.   NATURE BIOTECHNOLOGY

Brain organoids get vascularized

(2018) Madeline A Lancaster   NATURE BIOTECHNOLOGY

Methods for fabrication and evaluation of a 3D microengineered model of myelinated peripheral nerve

(2018) Parastoo Khoshakhlagh et al.   Journal of Neural Engineering

A microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers

(2018) Sandra Gribi et al.   Nature Communications

Integrating perfusable vascular networks with a three-dimensional tissue in a microfluidic device

(2017) Yuji Nashimoto et al.   Integrative Biology

High Density Individually Addressable Nanowire Arrays Record Intracellular Activity from Primary Rodent and Human Stem Cell Derived Neurons

(2017) Ren Liu et al.   NANO LETTERS

Paper-based patterned 3D neural cultures as a tool to study network activity on multielectrode arrays

(2017) Harald Dermutz et al.   RSC Advances

Design of Cultured Neuron Networks in vitro with Predefined Connectivity Using Asymmetric Microfluidic Channels

(2017) Arseniy Gladkov et al.   Scientific Reports

A mini-review on functional nucleic acids-based heavy metal ion detection

(2016) Shenshan Zhan et al.   BIOSENSORS & BIOELECTRONICS

Development-on-chip:in vitroneural tube patterning with a microfluidic device

(2016) Christopher J. Demers et al.   DEVELOPMENT

Development of a spontaneously active dorsal root ganglia assay using multiwell multielectrode arrays

(2016) Kim Newberry et al.   JOURNAL OF NEUROPHYSIOLOGY

Microfluidics and microbial engineering

(2016) Songzi Kou et al.   LAB ON A CHIP

Correction: 3D printed nervous system on a chip

(2016) Blake N. Johnson et al.   LAB ON A CHIP

The upcoming 3D-printing revolution in microfluidics

(2016) Nirveek Bhattacharjee et al.   LAB ON A CHIP

Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system

(2016) Michael J Workman et al.   NATURE MEDICINE

Functional 3D Neural Mini-Tissues from Printed Gel-Based Bioink and Human Neural Stem Cells

(2016) Qi Gu et al.   Advanced Healthcare Materials

Microfluidic device for the formation of optically excitable, three-dimensional, compartmentalized motor units

(2016) S. G. M. Uzel et al.   Science Advances

Peripheral nerve regeneration: Experimental strategies and future perspectives

(2015) Alessandro Faroni et al.   ADVANCED DRUG DELIVERY REVIEWS

Advanced MEMS-based technologies and displays

(2015) Ji Ma   DISPLAYS

Microengineered peripheral nerve-on-a-chip for preclinical physiological testing

(2015) Renee M. Huval et al.   LAB ON A CHIP

Organs-on-chips at the frontiers of drug discovery

(2015) Eric W. Esch et al.   NATURE REVIEWS DRUG DISCOVERY

Engineering-Aligned 3D Neural Circuit in Microfluidic Device

(2015) Seokyoung Bang et al.   Advanced Healthcare Materials

Evaluation of 3D Printing and Its Potential Impact on Biotechnology and the Chemical Sciences

(2014) Bethany C. Gross et al.   ANALYTICAL CHEMISTRY

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

Organogenesis in a dish: Modeling development and disease using organoid technologies

(2014) M. A. Lancaster et al.   SCIENCE

Cell adhesion promotion strategies for signal transduction enhancement in microelectrode array in vitro electrophysiology: An introductory overview and critical discussion

(2013) Axel Blau   CURRENT OPINION IN COLLOID & INTERFACE SCIENCE

Regeneration-on-a-chip? The perspectives on use of microfluidics in regenerative medicine

(2013) Björn Harink et al.   LAB ON A CHIP

Spatiotemporally Controlled and Multifactor Involved Assay of Neuronal Compartment Regeneration after Chemical Injury in an Integrated Microfluidics

(2012) Li Li et al.   ANALYTICAL CHEMISTRY

An aligned 3D neuronal-glial co-culture model for peripheral nerve studies

(2012) Muhammad F.B. Daud et al.   BIOMATERIALS

Integration of pre-aligned liquid metal electrodes for neural stimulation within a user-friendly microfluidic platform

(2012) Nicholas Hallfors et al.   LAB ON A CHIP

A modular approach to create a neurovascular unit-on-a-chip

(2012) Anil Kumar H. Achyuta et al.   LAB ON A CHIP

Vertical nanowire electrode arrays as a scalable platform for intracellular interfacing to neuronal circuits

(2012) Jacob T. Robinson et al.   Nature Nanotechnology

Let there be chip—towards rapid prototyping of microfluidic devices: one-step manufacturing processes

(2011) Ansgar Waldbaur et al.   Analytical Methods

Combined chemical and topographical guidance cues for directing cytoarchitectural polarization in primary neurons

(2011) Adrienne C. Greene et al.   BIOMATERIALS

Modeling extracellular electrical neural stimulation: From basic understanding to MEA-based applications

(2011) Sébastien Joucla et al.   JOURNAL OF PHYSIOLOGY-PARIS

Ensembles of engineered cardiac tissues for physiological and pharmacological study: Heart on a chip

(2011) Anna Grosberg et al.   LAB ON A CHIP

Artificial niche microarrays for probing single stem cell fate in high throughput

(2011) Samy Gobaa et al.   NATURE METHODS

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

Technique for Real-Time Measurements of Endothelial Permeability in a Microfluidic Membrane Chip Using Laser-Induced Fluorescence Detection

(2010) Edmond W. K. Young et al.   ANALYTICAL CHEMISTRY

Micropatterning as a tool to decipher cell morphogenesis and functions

(2010) M. Thery   JOURNAL OF CELL SCIENCE

A high-throughput microfluidic assay to study neurite response to growth factor gradients

(2010) Chandrasekhar R. Kothapalli et al.   LAB ON A CHIP

Microfluidic Local Perfusion Chambers for the Visualization and Manipulation of Synapses

(2010) Anne M. Taylor et al.   NEURON

A microfabricated platform for high-throughput unconfined compression of micropatterned biomaterial arrays

(2009) Christopher Moraes et al.   BIOMATERIALS

Mechanical breaking of microtubules in axons during dynamic stretch injury underlies delayed elasticity, microtubule disassembly, and axon degeneration

(2009) Min D. Tang-Schomer et al.   FASEB JOURNAL

Microfabricated arrays for high-throughput screening of cellular response to cyclic substrate deformation

(2009) Christopher Moraes et al.   LAB ON A CHIP

Differentiation of Neural Progenitor Cells in a Microfluidic Chip-Generated Cytokine Gradient

(2009) Joong Yull Park et al.   STEM CELLS

Identification of Surface Heterogeneity Effects in Cyclic Voltammograms Derived from Analysis of an Individually Addressable Gold Array Electrode

(2008) Chong-Yong Lee et al.   ANALYTICAL CHEMISTRY

Neurite growth in 3D collagen gels with gradients of mechanical properties

(2008) Harini G. Sundararaghavan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Biomolecular gradients in cell culture systems

(2007) Thomas M. Keenan et al.   LAB ON A CHIP

Incorporation of 3T3-L1 Cells To Mimic Bioaccumulation in a Microscale Cell Culture Analog Device for Toxicity Studies

(2004) Kwanchanok Viravaidya et al.   BIOTECHNOLOGY PROGRESS