Mutations of the dimerization site of glycoprotein (GP) VI result in abolished expression

Structural insights into collagen binding by platelet receptor glycoprotein VI

(2022) Louris J. Feitsma et al.   BLOOD

Targeting of a Conserved Epitope in Mouse and Human GPVI Differently Affects Receptor Function

(2022) Stefano Navarro et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glenzocimab: A GPVI (Glycoprotein VI)-Targeted Potential Antiplatelet Agent for the Treatment of Acute Ischemic Stroke

(2022) Surasak Wichaiyo et al.   STROKE

Targeting platelet GPVI with glenzocimab: a novel mechanism for inhibition

(2022) Philippe Billiald et al.   Blood Advances

Structure-function relationship of the platelet glycoprotein VI (GPVI) receptor: does it matter if it is a dimer or monomer?

(2021) Joanne C. Clark et al.   PLATELETS

Evidence that GPVI is expressed as a mixture of monomers and dimers, and that the D2 domain is not essential for GPVI activation

(2021) Joanne Clark et al.   THROMBOSIS AND HAEMOSTASIS

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Temporal Roles of Platelet and Coagulation Pathways in Collagen- and Tissue Factor-Induced Thrombus Formation

(2021) Stefano Navarro et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Functional significance of the platelet immune receptors GPVI and CLEC-2

(2019) Julie Rayes et al.   JOURNAL OF CLINICAL INVESTIGATION

Thrombo-inflammation in acute ischaemic stroke — implications for treatment

(2019) Guido Stoll et al.   Nature Reviews Neurology

Easi-CRISPR for creating knock-in and conditional knockout mouse models using long ssDNA donors

(2017) Hiromi Miura et al.   Nature Protocols

Discovery of GS-9973, a Selective and Orally Efficacious Inhibitor of Spleen Tyrosine Kinase

(2014) Kevin S. Currie et al.   JOURNAL OF MEDICINAL CHEMISTRY