Temporal Roles of Platelet and Coagulation Pathways in Collagen- and Tissue Factor-Induced Thrombus Formation

Long-term platelet priming after glycoprotein VI stimulation in comparison to Protease-Activating Receptor (PAR) stimulation

(2021) Jinmi Zou et al.   PLoS One

Multiparameter microfluidics assay of thrombus formation reveals increased sensitivity to contraction and antiplatelet agents at physiological temperature

(2021) Linda Herfs et al.   THROMBOSIS RESEARCH

Congenital Afibrinogenemia and Hypofibrinogenemia: Laboratory and Genetic Testing in Rare Bleeding Disorders with Life-Threatening Clinical Manifestations and Challenging Management

(2021) Tomas Simurda et al.   Diagnostics

Tissue factor in atherosclerosis and atherothrombosis

(2020) Steven P. Grover et al.   ATHEROSCLEROSIS

Platelet-primed interactions of coagulation and anticoagulation pathways in flow-dependent thrombus formation

(2020) Sanne L. N. Brouns et al.   Scientific Reports

Flow studies on human GPVI-deficient blood under coagulating and noncoagulating conditions

(2020) Magdolna Nagy et al.   Blood Advances

Nonredundant Roles of Platelet Glycoprotein VI and Integrin αIIbβ3 in Fibrin-Mediated Microthrombus Formation

(2020) Gina Perrella et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelet calcium signaling by G-protein coupled and ITAM-linked receptors regulating anoctamin-6 and procoagulant activity

(2020) Delia I. Fernández et al.   PLATELETS

Functional significance of the platelet immune receptors GPVI and CLEC-2

(2019) Julie Rayes et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces

(2019) Natalie J. Jooss et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Whole Blood Based Multiparameter Assessment of Thrombus Formation in Standard Microfluidic Devices to Proxy In Vivo Haemostasis and Thrombosis

(2019) Isabella Provenzale et al.   Micromachines

Rivaroxaban Reduces Arterial Thrombosis by Inhibition of FXa-Driven Platelet Activation via Protease Activated Receptor-1

(2019) Tobias Petzold et al.   CIRCULATION RESEARCH

Thrombus Formation and Propagation in the Onset of Cardiovascular Events

(2018) Yujiro Asada et al.   Journal of Atherosclerosis and Thrombosis

Platelet collagen receptor Glycoprotein VI-dimer recognizes fibrinogen and fibrin through their D-domains, contributing to platelet adhesion and activation during thrombus formation

(2018) I. Induruwa et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A synthesis approach of mouse studies to identify genes and proteins in arterial thrombosis and bleeding

(2018) Constance C. F. M. J. Baaten et al.   BLOOD

High-throughput elucidation of thrombus formation reveals sources of platelet function variability

(2018) Johanna P. van Geffen et al.   HAEMATOLOGICA

Platelet biology and functions: new concepts and clinical perspectives

(2018) Paola E. J. van der Meijden et al.   Nature Reviews Cardiology

Variable impairment of platelet functions in patients with severe, genetically linked immune deficiencies

(2017) Magdolna Nagy et al.   HAEMATOLOGICA

Blockade of protease-activated receptor-4 (PAR4) provides robust antithrombotic activity with low bleeding

(2017) Pancras C. Wong et al.   Science Translational Medicine

Variable impairment of platelet functions in patients with severe, genetically linked immune deficiencies

(2017) Magdolna Nagy et al.   HAEMATOLOGICA

Multi-Constituent Simulation of Thrombus Deposition

(2017) Wei-Tao Wu et al.   Scientific Reports

Platelet Control of Fibrin Distribution and Microelasticity in Thrombus Formation Under FlowSignificance

(2016) Frauke Swieringa et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proteinase-activated receptors (PARs) as targets for antiplatelet therapy

(2016) Margaret Cunningham et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Coagulation factors bound to procoagulant platelets concentrate in cap structures to promote clotting

(2016) N. A. Podoplelova et al.   BLOOD

Inhibition of protease-activated receptor 4 impairs platelet procoagulant activity during thrombus formation in human blood

(2016) S. L. French et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet glycoprotein VI binds to polymerized fibrin and promotes thrombin generation

(2015) E. Mammadova-Bach et al.   BLOOD

Fibrin activates GPVI in human and mouse platelets

(2015) O. M. Alshehri et al.   BLOOD

Rate-limiting roles of the tenase complex of factors VIII and IX in platelet procoagulant activity and formation of platelet-fibrin thrombi under flow

(2015) F. Swieringa et al.   HAEMATOLOGICA

Spatiotemporal regulation of coagulation and platelet activation during the hemostatic responsein vivo

(2015) L. Ivanciu et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Rate-limiting roles of the tenase complex of factors VIII and IX in platelet procoagulant activity and formation of platelet-fibrin thrombi under flow

(2015) F. Swieringa et al.   HAEMATOLOGICA

Factor XII Regulates the Pathological Process of Thrombus Formation on Ruptured Plaques

(2014) Marijke J.E. Kuijpers et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A systems approach to hemostasis: 3. Thrombus consolidation regulates intrathrombus solute transport and local thrombin activity

(2014) T. J. Stalker et al.   BLOOD

A systems approach to hemostasis: 2. Computational analysis of molecular transport in the thrombus microenvironment

(2014) M. Tomaiuolo et al.   BLOOD

Insights into platelet-based control of coagulation

(2014) Susanne M. de Witt et al.   THROMBOSIS RESEARCH

Identification of platelet function defects by multi-parameter assessment of thrombus formation

(2014) Susanne M. de Witt et al.   Nature Communications

Combined In Vivo Depletion of Glycoprotein VI and C-Type Lectin-Like Receptor 2 Severely Compromises Hemostasis and Abrogates Arterial Thrombosis in Mice

(2013) Markus Bender et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Dual Mechanism of Integrin αIIbβ3Closure in Procoagulant Platelets

(2013) Nadine J. A. Mattheij et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flow-dependent thrombin and fibrin generationin vitro: opportunities for standardization: communication from SSC of the ISTH

(2013) K. B. Neeves et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

New Fundamentals in Hemostasis

(2013) Henri H. Versteeg et al.   PHYSIOLOGICAL REVIEWS

Thrombus Growth and Embolism on Tissue Factor-Bearing Collagen Surfaces Under Flow

(2012) Thomas V. Colace et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelet-based coagulation: different populations, different functions

(2012) J. W. M. HEEMSKERK et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Measurement of whole blood thrombus formation using parallel-plate flow chambers – a practical guide

(2012) Roger Van Kruchten et al.   PLATELETS

Genetic and antibody-induced glycoprotein VI deficiency equally protects mice from mechanically and FeCl3-induced thrombosis

(2011) M. BENDER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet adhesion and activation mechanisms in arterial thrombosis and ischaemic stroke

(2011) B. NIESWANDT et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet receptor signaling in thrombus formation

(2010) David Stegner et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Non-redundant Roles of Phosphoinositide 3-Kinase Isoforms α and β in Glycoprotein VI-induced Platelet Signaling and Thrombus Formation

(2009) Karen Gilio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Determination of surface tissue factor thresholds that trigger coagulation at venous and arterial shear rates: amplification of 100 fM circulating tissue factor requires flow

(2008) U. M. Okorie et al.   BLOOD

Complementary roles of platelets and coagulation in thrombus formation on plaques acutely ruptured by targeted ultrasound treatment: a novel intravital model

(2008) M. J. E. KUIJPERS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Key Role of Platelet Procoagulant Activity in Tissue Factor-and Collagen-Dependent Thrombus Formation in Arterioles and VenulesIn VivoDifferential Sensitivity to Thrombin Inhibition

(2008) Marijke J.E. Kuijpers et al.   MICROCIRCULATION