Alternative splicing of CEACAM1 by hypoxia-inducible factor–1α enhances tolerance to hepatic ischemia in mice and humans

Co-administration of lipopolysaccharide and d-galactosamine induces genotoxicity in mouse liver

(2021) Wenjing Dong et al.   Scientific Reports

PTBP1 Targets ILK to Regulate the Hypoxia-Induced Phenotypic Transformation of Pulmonary Artery Smooth Muscle Cells

(2021) Gaoliang Yan et al.   Drug Design Development and Therapy

HIF-1α is a negative regulator of interferon regulatory factors: Implications for interferon production by hypoxic monocytes

(2021) Travis Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ischemic heart injury leads to HIF1-dependent differential splicing of CaMK2γ

(2021) Allison Lesher Williams et al.   Scientific Reports

Myeloid Ikaros–SIRT1 signaling axis regulates hepatic inflammation and pyroptosis in ischemia-stressed mouse and human liver

(2021) Kentaro Kadono et al.   JOURNAL OF HEPATOLOGY

Hepatic CEACAM1 expression indicates donor liver quality and prevents early transplantation injury

(2020) Kojiro Nakamura et al.   JOURNAL OF CLINICAL INVESTIGATION

CEACAM1 and molecular signaling pathways to expand the liver transplant donor pool

(2020) Samer Tohme et al.   JOURNAL OF CLINICAL INVESTIGATION

CEACAM1 inhibited IκB-α/NF-κB signal pathway via targeting MMP-9/TIMP-1 axis in diabetic atherosclerosis

(2020) Jie Yu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Hypoxia-induced alternative splicing: the 11th Hallmark of Cancer

(2020) Antonietta Rosella Farina et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Hyperinsulinemia drives hepatic insulin resistance in male mice with liver-specific Ceacam1 deletion independently of lipolysis

(2019) Hilda E. Ghadieh et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Heme Oxygenase-1 dictates innate – adaptive immune phenotype in human liver transplantation

(2019) Kentaro Kadono et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Human Antigen R (HuR): A New Regulator of Heme Oxygenase‐1 Cytoprotection in Mouse and Human Liver Transplant Injury

(2019) Kenneth J. Dery et al.   HEPATOLOGY

DMOG, a Prolyl Hydroxylase Inhibitor, Increases Hemoglobin Levels without Exacerbating Hypertension and Renal Injury in Salt-Sensitive Hypertensive Rats

(2019) Sota Kato et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

CEACAM1 resists hypoxia-induced inhibition of tube formation of human dermal lymphatic endothelial cells

(2018) Qi Xie et al.   CELLULAR SIGNALLING

Interferon regulatory factor 1 and a variant of heterogeneous nuclear ribonucleoprotein L coordinately silence the gene for adhesion protein CEACAM1

(2018) Kenneth J. Dery et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIF stabilizers in the management of renal anemia: from bench to bedside to pediatrics

(2018) Dalvir Kular et al.   PEDIATRIC NEPHROLOGY

Macrophage heme oxygenase-1-SIRT1-p53 axis regulates sterile inflammation in liver ischemia-reperfusion injury

(2017) Kojiro Nakamura et al.   JOURNAL OF HEPATOLOGY

Impact of Alternative Splicing on the Human Proteome

(2017) Yansheng Liu et al.   Cell Reports

Alternative RNA Splicing in the Pathogenesis of Liver Disease

(2017) Nicholas J. G. Webster   Frontiers in Endocrinology

Biliary complications following liver transplantation

(2017) Gursimran Kochhar et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Hypoxia-inducible factor 3 biology: complexities and emerging themes

(2016) Cunming Duan   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes

(2016) Andrea Stoehr et al.   CARDIOVASCULAR RESEARCH

The hnRNP family: insights into their role in health and disease

(2016) Thomas Geuens et al.   HUMAN GENETICS

Novel strategy to decrease reperfusion injuries and improve function of cold-preserved livers using normothermic ex vivo liver perfusion machine

(2016) Babak Banan et al.   LIVER TRANSPLANTATION

Effects of warm ischemia and reperfusion on the liver microcirculatory phenotype of rats: underlying mechanisms and pharmacological therapy

(2016) Diana Hide et al.   Scientific Reports

A novel effect of DMOG on cell metabolism: direct inhibition of mitochondrial function precedes HIF target gene expression

(2015) Alexander V. Zhdanov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance

(2015) Qusai Y. Al-Share et al.   DIABETES

Bilirubin Activates Transcription of HIF-1α in Human Proximal Tubular Cells Cultured in the Physiologic Oxygen Content

(2014) Sung Gyun Kim et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

IRF-1 regulates alternative mRNA splicing of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in breast epithelial cells generating an immunoreceptor tyrosine-based inhibition motif (ITIM) containing isoform

(2014) Kenneth J Dery et al.   Molecular Cancer

Hypoxia Regulates Alternative Splicing of HIF and non-HIF Target Genes

(2014) J. A. Sena et al.   MOLECULAR CANCER RESEARCH

ELAVL1 regulates alternative splicing of eIF4E transporter to promote postnatal angiogenesis

(2014) Sung-Hee Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis

(2013) Nicole Beauchemin et al.   CANCER AND METASTASIS REVIEWS

Transcriptional regulation by hypoxia inducible factors

(2013) Veronica L. Dengler et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Phosphorylation of CEACAM1 Molecule by Calmodulin Kinase IID in a Three-dimensional Model of Mammary Gland Lumen Formation

(2013) Tung Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Liver Ischemia and Reperfusion Injury: New Insights into Mechanisms of Innate-Adaptive Immune-Mediated Tissue Inflammation

(2011) Y. Zhai et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Mechanistic Control of Carcinoembryonic Antigen-related Cell Adhesion Molecule-1 (CEACAM1) Splice Isoforms by the Heterogeneous Nuclear Ribonuclear Proteins hnRNP L, hnRNP A1, and hnRNP M

(2011) Kenneth J. Dery et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional diversity of the hnRNPs: past, present and perspectives

(2010) Siew Ping Han et al.   BIOCHEMICAL JOURNAL

Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by hypoxia-inducible factor-1α

(2010) Florian Schelter et al.   CLINICAL & EXPERIMENTAL METASTASIS

CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injury

(2008) Nobuyuki Tamaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

CEACAM1 and the regulation of mucosal inflammation

(2008) T Nagaishi et al.   Mucosal Immunology