Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes

A novel effect of DMOG on cell metabolism: direct inhibition of mitochondrial function precedes HIF target gene expression

(2015) Alexander V. Zhdanov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Protein Hydroxylation Catalyzed by 2-Oxoglutarate-dependent Oxygenases

(2015) Suzana Markolovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

2016 update of the PRIDE database and its related tools

(2015) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Identification of prolyl hydroxylation modifications in mammalian cell proteins

(2015) Patrick R. Arsenault et al.   PROTEOMICS

Dynamic profiling of the protein life cycle in response to pathogens

(2015) M. Jovanovic et al.   SCIENCE

A cost-effective and efficient reprogramming platform for large-scale production of integration-free human induced pluripotent stem cells in chemically defined culture

(2015) Jeanette Beers et al.   Scientific Reports

Protein kinetic signatures of the remodeling heart following isoproterenol stimulation

(2014) Maggie P.Y. Lam et al.   JOURNAL OF CLINICAL INVESTIGATION

PHD3-mediated prolyl hydroxylation of nonmuscle actin impairs polymerization and cell motility

(2014) Weibo Luo et al.   MOLECULAR BIOLOGY OF THE CELL

Chemically defined generation of human cardiomyocytes

(2014) Paul W Burridge et al.   NATURE METHODS

Network-based association of hypoxia-responsive genes with cardiovascular diseases

(2014) Rui-Sheng Wang et al.   NEW JOURNAL OF PHYSICS

The Prolyl Hydroxylase Inhibitor Dimethyloxalylglycine Enhances Dentin Sialophoshoprotein Expression through VEGF-Induced Runx2 Stabilization

(2014) Saeed Ur Rahman et al.   PLoS One

Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth

(2014) M. J. Katz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation

(2014) R. S. Singleton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy

(2014) C. Loenarz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxamirs and Mitochondrial Metabolism

(2013) Katherine A. Cottrill et al.   ANTIOXIDANTS & REDOX SIGNALING

Genome-wide Analysis Reveals SR Protein Cooperation and Competition in Regulated Splicing

(2013) Shatakshi Pandit et al.   MOLECULAR CELL

PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response

(2012) Liang Xie et al.   JOURNAL OF CLINICAL INVESTIGATION

RBM25/LUC7L3 Function in Cardiac Sodium Channel Splicing Regulation of Human Heart Failure

(2012) Ge Gao et al.   TRENDS IN CARDIOVASCULAR MEDICINE

A Review of Human Pluripotent Stem Cell-Derived Cardiomyocytes for High-Throughput Drug Discovery, Cardiotoxicity Screening, and Publication Standards

(2012) Nicholas M. Mordwinkin et al.   Journal of Cardiovascular Translational Research

SDH mutations in cancer

(2011) Chiara Bardella et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Inhibition of 2-oxoglutarate dependent oxygenases

(2011) Nathan R. Rose et al.   CHEMICAL SOCIETY REVIEWS

Activation of the prolyl-hydroxylase oxygen-sensing signal cascade leads to AMPK activation in cardiomyocytes

(2011) Hong Yan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Systems-wide Proteomic Analysis in Mammalian Cells Reveals Conserved, Functional Protein Turnover

(2011) Sidney B. Cambridge et al.   JOURNAL OF PROTEOME RESEARCH

Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1

(2011) J.-N. Boeckel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prolyl 4-hydroxylase

(2010) Kelly L. Gorres et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

OGFOD1, a member of the 2-oxoglutarate and iron dependent dioxygenase family, functions in ischemic signaling

(2010) Ken Saito et al.   FEBS LETTERS

OGFOD1, a Novel Modulator of Eukaryotic Translation Initiation Factor 2  Phosphorylation and the Cellular Response to Stress

(2010) K. A. Wehner et al.   MOLECULAR AND CELLULAR BIOLOGY

Prolyl hydroxylases as regulators of cell metabolism: Figure 1

(2009) Houda Boulahbel et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Oxygen Sensors at the Crossroad of Metabolism

(2009) Julián Aragonés et al.   Cell Metabolism

Surviving hypoxia by modulation of mRNA translation rate

(2009) Michael Fähling   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice

(2009) Xing Shen et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Oxygen-Regulated  2-Adrenergic Receptor Hydroxylation by EGLN3 and Ubiquitylation by pVHL

(2009) L. Xie et al.   Science Signaling

Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts

(2008) J. R. Sanford et al.   GENOME RESEARCH

Proteomics-based Identification of Novel Factor Inhibiting Hypoxia-inducible Factor (FIH) Substrates Indicates Widespread Asparaginyl Hydroxylation of Ankyrin Repeat Domain-containing Proteins

(2008) Matthew E. Cockman et al.   MOLECULAR & CELLULAR PROTEOMICS