DUSP1/MKP-1 represents another piece in the P2X7R intracellular signaling puzzle in cerebellar cells: our last journey with Mª Teresa along the purinergic pathways of Eden

Nucleotide-Induced Nanoscale Changes in the Mechanical Properties of Rat Cerebellar Astrocytes: Selective Stimulation and Blocking of the Purinergic Receptor P2X7

(2022) Juan Carlos Gil-Redondo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

BCI, an inhibitor of the DUSP1 and DUSP6 dual specificity phosphatases, enhances P2X7 receptor expression in neuroblastoma cells

(2022) María Benito-León et al.   Frontiers in Cell and Developmental Biology

Salient brain entities labelled in P2rx7-EGFP reporter mouse embryos include the septum, roof plate glial specializations and circumventricular ependymal organs

(2021) Felipe Ortega et al.   Brain Structure & Function

Dual-specificity phosphatases in mental and neurological disorders

(2020) Ning An et al.   PROGRESS IN NEUROBIOLOGY

Targeted inhibition of the dual specificity phosphatases DUSP1 and DUSP6 suppress MPNST growth via JNK

(2019) Annmarie Ramkissoon et al.   CLINICAL CANCER RESEARCH

Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss

(2019) Adelaida M Celaya et al.   eLife

P2X7 Interactions and Signaling – Making Head or Tail of It

(2019) Robin Kopp et al.   Frontiers in Molecular Neuroscience

P2X7 Nucleotide and EGF Receptors Exert Dual Modulation of the Dual-Specificity Phosphatase 6 (MKP-3) in Granule Neurons and Astrocytes, Contributing to Negative Feedback on ERK Signaling

(2018) Mª José Queipo et al.   Frontiers in Molecular Neuroscience

Dual-specificity MAP kinase phosphatases in health and disease

(2018) Ole-Morten Seternes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Tumor Cell-Selective Inhibitor of Mitogen-Activated Protein Kinase Phosphatases Sensitizes Breast Cancer Cells to Lymphokine-Activated Killer Cell Activity

(2017) Christof T. Kaltenmeier et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The ATP-Gated P2X7 Receptor As a Target for the Treatment of Drug-Resistant Epilepsy

(2017) Edward Beamer et al.   Frontiers in Neuroscience

Prostaglandin E2 Impairs P2Y2/P2Y4 Receptor Signaling in Cerebellar Astrocytes via EP3 Receptors

(2017) Lucía Paniagua-Herranz et al.   Frontiers in Pharmacology

Macrophage responses to lipopolysaccharide are modulated by a feedback loop involving prostaglandin E2, dual specificity phosphatase 1 and tristetraprolin

(2017) Tina Tang et al.   Scientific Reports

Deletion of Neurotrophin Signaling through the Glucocorticoid Receptor Pathway Causes Tau Neuropathology

(2016) Margarita Arango-Lievano et al.   Scientific Reports

Differential expression profiles and roles of inducible DUSPs and ERK1/2-specific constitutive DUSP6 and DUSP7 in microglia

(2015) Ji-Eun Ham et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PI3K/Akt signaling pathway triggers P2X7 receptor expression as a pro-survival factor of neuroblastoma cells under limiting growth conditions

(2015) Rosa Gómez-Villafuertes et al.   Scientific Reports

Dual-specificity phosphatases: critical regulators with diverse cellular targets

(2015) Kate I. Patterson et al.   BIOCHEMICAL JOURNAL

Neuroprotection elicited by P2Y13 receptors against genotoxic stress by inducing DUSP2 expression and MAPK signaling recovery

(2014) Verónica Morente et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Inhibition of mitogen-activated protein kinase phosphatase-1 (MKP-1) increases experimental stroke injury

(2014) Lin Liu et al.   EXPERIMENTAL NEUROLOGY

Mitogen-Activated Protein Kinase Phosphatase (MKP)-1 in Nervous System Development and Disease

(2014) Louise M. Collins et al.   MOLECULAR NEUROBIOLOGY

Selective Impairment of P2Y Signaling by Prostaglandin E2 in Macrophages: Implications for Ca2+-Dependent Responses

(2013) P. G. Traves et al.   JOURNAL OF IMMUNOLOGY

MAP Kinase Phosphatase 1 (MKP-1/DUSP1) Is Neuroprotective in Huntington's Disease via Additive Effects of JNK and p38 Inhibition

(2013) D. M. Taylor et al.   JOURNAL OF NEUROSCIENCE

Mitogen-Activated Protein Kinase Phosphatase (MKP)-1 as a Neuroprotective Agent: Promotion of the Morphological Development of Midbrain Dopaminergic Neurons

(2013) Louise M. Collins et al.   NEUROMOLECULAR MEDICINE

Expression of P2X7 Receptor Increases In Vivo Tumor Growth

(2012) E. Adinolfi et al.   CANCER RESEARCH

MKP-1: A critical phosphatase in the biology of macrophages controlling the switch between proliferation and activation

(2012) Mònica Comalada et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Over-expression of map kinase phosphatase-1 (MKP-1) suppresses neuronal death through regulating JNK signaling in hypoxia/re-oxygenation

(2011) Shunsuke Koga et al.   BRAIN RESEARCH

Tissue-nonspecific alkaline phosphatase promotes axonal growth of hippocampal neurons

(2011) M. Díez-Zaera et al.   MOLECULAR BIOLOGY OF THE CELL

In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases

(2011) Juan Ignacio Diaz-Hernandez et al.   NEUROBIOLOGY OF AGING

ERK1/2 activation is involved in the neuroprotective action of P2Y13 and P2X7 receptors against glutamate excitotoxicity in cerebellar granule neurons

(2011) Felipe Ortega et al.   NEUROPHARMACOLOGY

P2X7, NMDA and BDNF receptors converge on GSK3 phosphorylation and cooperate to promote survival in cerebellar granule neurons

(2010) Felipe Ortega et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mitogen-activated protein kinase phosphatase-1 (MKP-1) in retinal ischemic preconditioning

(2010) John C. Dreixler et al.   EXPERIMENTAL EYE RESEARCH

Mechanisms of protein kinase D activation in response to P2Y2and P2X7 receptors in primary astrocytes

(2010) Luz MarÍa G. Carrasquero et al.   GLIA

Mkp1 Is a c-Jun Target Gene That Antagonizes JNK-Dependent Apoptosis in Sympathetic Neurons

(2010) M. Kristiansen et al.   JOURNAL OF NEUROSCIENCE

A negative regulator of MAP kinase causes depressive behavior

(2010) Vanja Duric et al.   NATURE MEDICINE

The MAP kinase phosphatase MKP-1 regulates BDNF-induced axon branching

(2010) Freddy Jeanneteau et al.   NATURE NEUROSCIENCE

Altered P2X7-receptor level and function in mouse models of Huntington’s disease and therapeutic efficacy of antagonist administration

(2009) Miguel Díaz-Hernández et al.   FASEB JOURNAL

P2X7and P2Y13purinergic receptors mediate intracellular calcium responses to BzATP in rat cerebellar astrocytes

(2009) Luz María G. Carrasquero et al.   JOURNAL OF NEUROCHEMISTRY

Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages

(2009) Gabriela Molina et al.   Nature Chemical Biology

Different properties of P2X7 receptor in hippocampal and cortical astrocytes

(2009) Fabio Bianco et al.   Purinergic Signalling

Negative and Positive Regulation of MAPK Phosphatase 3 Controls Platelet-derived Growth Factor-induced Erk Activation

(2008) Aleksandra Jurek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons

(2008) M. Diaz-Hernandez et al.   JOURNAL OF CELL SCIENCE

Cisplatin-mediated activation of extracellular signal-regulated kinases 12 (ERK12) by inhibition of ERK12 phosphatases

(2008) Agata Gozdz et al.   JOURNAL OF NEUROCHEMISTRY

MKP-1 mRNA Stabilization and Translational Control by RNA-Binding Proteins HuR and NF90

(2008) Y. Kuwano et al.   MOLECULAR AND CELLULAR BIOLOGY

P2X7 Receptors in Oligodendrocytes: A Novel Target for Neuroprotection

(2008) Carlos Matute   MOLECULAR NEUROBIOLOGY

Glutamate release and synapsin-I phosphorylation induced by P2X7 receptors activation in cerebellar granule neurons

(2008) David León et al.   NEUROCHEMISTRY INTERNATIONAL

Reciprocal regulation of extracellular signal regulated kinase 1/2 and mitogen activated protein kinase phosphatase-3

(2008) Nicholette A. Zeliadt et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY