Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain Barrier Permeability: a Pharmacokinetics Study in Healthy and Stroke Animals
出版年份 2023 全文链接
标题
Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain Barrier Permeability: a Pharmacokinetics Study in Healthy and Stroke Animals
作者
关键词
-
出版物
PHARMACEUTICAL RESEARCH
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2023-10-14
DOI
10.1007/s11095-023-03619-5
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Permeability of Metformin across an In Vitro Blood–Brain Barrier Model during Normoxia and Oxygen-Glucose Deprivation Conditions: Role of Organic Cation Transporters (Octs)
- (2023) Sejal Sharma et al. Pharmaceutics
- Small molecule neurolysin activators, potential multi-mechanism agents for ischemic stroke therapy
- (2022) Shiva Hadi Esfahani et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- In-Vivo and Ex-Vivo Brain Uptake Studies of Peptidomimetic Neurolysin Activators in Healthy and Stroke Animals
- (2022) Saeideh Nozohouri et al. PHARMACEUTICAL RESEARCH
- Potential role of astrocyte angiotensin converting enzyme 2 in the neural transmission of COVID-19 and a neuroinflammatory state induced by smoking and vaping
- (2022) Yong Zhang et al. Fluids and Barriers of the CNS
- Targeting organic cation transporters at the blood-brain barrier to treat ischemic stroke in rats
- (2022) Joshua A. Stanton et al. EXPERIMENTAL NEUROLOGY
- Neurolysin substrates bradykinin, neurotensin and substance P enhance brain microvascular permeability in a human in vitro model
- (2021) Abraham J. Al‐Ahmad et al. JOURNAL OF NEUROENDOCRINOLOGY
- Discovery of First-in-Class Peptidomimetic Neurolysin Activators Possessing Enhanced Brain Penetration and Stability
- (2021) Md. Shafikur Rahman et al. JOURNAL OF MEDICINAL CHEMISTRY
- Identification and characterization of two structurally related dipeptides that enhance catalytic efficiency of neurolysin
- (2021) Srinidhi Jayaraman et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Glutamate Buffering Capacity and Blood-Brain Barrier Protection of Opioid Receptor Agonists Biphalin and Nociceptin
- (2021) Saeideh Nozohouri et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Novel approaches for the delivery of therapeutics in ischemic stroke
- (2020) Saeideh Nozohouri et al. DRUG DISCOVERY TODAY
- Challenging the Ischemic Core Concept in Acute Ischemic Stroke Imaging
- (2020) Mayank Goyal et al. STROKE
- Development of Simplified in Vitro P-Glycoprotein Substrate Assay and in Silico Prediction Models To Evaluate Transport Potential of P-Glycoprotein
- (2019) Rikiya Ohashi et al. MOLECULAR PHARMACEUTICS
- Stroke Treatment Academic Industry Roundtable X
- (2019) Sean I. Savitz et al. STROKE
- Peptidase neurolysin functions to preserve the brain after ischemic stroke in male mice
- (2019) Srinidhi Jayaraman et al. JOURNAL OF NEUROCHEMISTRY
- Brain Delivery of a Potent Opioid Receptor Agonist, Biphalin during Ischemic Stroke: Role of Organic Anion Transporting Polypeptide (OATP)
- (2019) Thamer H Albekairi et al. Pharmaceutics
- Peptidase neurolysin is an endogenous cerebroprotective mechanism in acute neurodegenerative disorders
- (2019) Vardan T. Karamyan MEDICAL HYPOTHESES
- Neurovascular unit transport responses to ischemia and common coexisting conditions: smoking and diabetes
- (2018) Ali E Sifat et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Functional up-regulation of endopeptidase neurolysin during post-acute and early recovery phases of experimental stroke in mouse brain
- (2013) Mamoon Rashid et al. JOURNAL OF NEUROCHEMISTRY
- Identification of Membrane-bound Variant of Metalloendopeptidase Neurolysin (EC 3.4.24.16) as the Non-angiotensin Type 1 (Non-AT1), Non-AT2Angiotensin Binding Site
- (2011) Naomi J. Wangler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Association of the Novel Non-AT1, Non-AT2 Angiotensin Binding Site with Neuronal Cell Death
- (2010) M. Rashid et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Molecular imaging of cell death
- (2009) Marijke De Saint-Hubert et al. METHODS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started