The autism-associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrain

MET Receptor Tyrosine Kinase Controls Dendritic Complexity, Spine Morphogenesis, and Glutamatergic Synapse Maturation in the Hippocampus

(2014) Shenfeng Qiu et al.   JOURNAL OF NEUROSCIENCE

A novel computational biostatistics approach implies impaired dephosphorylation of growth factor receptors as associated with severity of autism

(2014) K M Wittkowski et al.   Translational Psychiatry

The autism and schizophrenia associated gene CYFIP1 is critical for the maintenance of dendritic complexity and the stabilization of mature spines

(2014) M Pathania et al.   Translational Psychiatry

Integrative Functional Genomic Analyses Implicate Specific Molecular Pathways and Circuits in Autism

(2013) Neelroop N. Parikshak et al.   CELL

Synaptic and extrasynaptic location of the receptor tyrosine kinase met during postnatal development in the mouse neocortex and hippocampus

(2013) Kathie L. Eagleson et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Transcriptional regulation of the MET receptor tyrosine kinase gene by MeCP2 and sex-specific expression in autism and Rett syndrome

(2013) J T Plummer et al.   Translational Psychiatry

Pathogenic SYNGAP1 Mutations Impair Cognitive Development by Disrupting Maturation of Dendritic Spine Synapses

(2012) James P. Clement et al.   CELL

Hepatocyte growth factor mediates mesenchymal stem cell–induced recovery in multiple sclerosis models

(2012) Lianhua Bai et al.   NATURE NEUROSCIENCE

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Autism-Associated Promoter Variant in MET Impacts Functional and Structural Brain Networks

(2012) Jeffrey D. Rudie et al.   NEURON

Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities

(2012) H. Y. Zoghbi et al.   Cold Spring Harbor Perspectives in Biology

Autism genetics: searching for specificity and convergence

(2012) Jamee M Berg et al.   GENOME BIOLOGY

De Novo SYNGAP1 Mutations in Nonsyndromic Intellectual Disability and Autism

(2011) Fadi F. Hamdan et al.   BIOLOGICAL PSYCHIATRY

Oscillations and hippocampal–prefrontal synchrony

(2011) Joshua A Gordon   CURRENT OPINION IN NEUROBIOLOGY

Circuit-Specific Intracortical Hyperconnectivity in Mice with Deletion of the Autism-Associated Met Receptor Tyrosine Kinase

(2011) S. Qiu et al.   JOURNAL OF NEUROSCIENCE

Regulation of MET by FOXP2, Genes Implicated in Higher Cognitive Dysfunction and Autism Risk

(2011) Z. Mukamel et al.   JOURNAL OF NEUROSCIENCE

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Rare De Novo Variants Associated with Autism Implicate a Large Functional Network of Genes Involved in Formation and Function of Synapses

(2011) Sarah R. Gilman et al.   NEURON

Conserved Subcortical and Divergent Cortical Expression of Proteins Encoded by Orthologs of the Autism Risk Gene MET

(2010) Matthew C. Judson et al.   CEREBRAL CORTEX

Overexpression of the cell adhesion protein neuroligin-1 induces learning deficits and impairs synaptic plasticity by altering the ratio of excitation to inhibition in the hippocampus

(2010) Regina Dahlhaus et al.   HIPPOCAMPUS

Evidence of cell-nonautonomous changes in dendrite and dendritic spine morphology in the met-signaling-deficient mouse forebrain

(2010) Matthew C. Judson et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

Knockdown of DISC1 by In Utero Gene Transfer Disturbs Postnatal Dopaminergic Maturation in the Frontal Cortex and Leads to Adult Behavioral Deficits

(2010) Minae Niwa et al.   NEURON

Critical Period Plasticity Is Disrupted in the Barrel Cortex of Fmr1 Knockout Mice

(2010) Emily G. Harlow et al.   NEURON

Further evidence for the role of MET in autism susceptibility

(2010) Ismail Thanseem et al.   NEUROSCIENCE RESEARCH

Rho and Ras GTPases in Axon Growth, Guidance, and Branching

(2010) A. Hall et al.   Cold Spring Harbor Perspectives in Biology

Further evidence that the rs1858830 C variant in the promoter region of theMETgene is associated with autistic disorder

(2009) Pamela B. Jackson et al.   Autism Research

Dynamic gene and protein expression patterns of the autism-associated met receptor tyrosine kinase in the developing mouse forebrain

(2009) Matthew C. Judson et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Laminar Specificity of Functional Input to Distinct Types of Inhibitory Cortical Neurons

(2009) X. Xu et al.   JOURNAL OF NEUROSCIENCE

Synaptic Circuit Abnormalities of Motor-Frontal Layer 2/3 Pyramidal Neurons in an RNA Interference Model of Methyl-CpG-Binding Protein 2 Deficiency

(2009) L. Wood et al.   JOURNAL OF NEUROSCIENCE

Human-specific transcriptional regulation of CNS development genes by FOXP2

(2009) Genevieve Konopka et al.   NATURE

Coordinated Changes in Dendritic Arborization and Synaptic Strength during Neural Circuit Development

(2009) Yi-Rong Peng et al.   NEURON

Automated quantification of dendritic spine density and spine head diameter in medium spiny neurons of the nucleus accumbens

(2008) Haowei Shen et al.   Brain Structure & Function