In vitro and in vivo neuroprotective effects of cJun N-terminal kinase inhibitors on retinal ganglion cells

Inhibition of thioredoxin-1 with siRNA exacerbates apoptosis by activating the ASK1-JNK/p38 pathway in brain of a stroke model rats

(2015) Xiaoying Wu et al.   BRAIN RESEARCH

Chitosan oligosaccharides prevented retinal ischemia and reperfusion injury via reduced oxidative stress and inflammation in rats

(2015) I-Mo Fang et al.   EXPERIMENTAL EYE RESEARCH

A combination of four active compounds alleviates cerebral ischemia-reperfusion injury in correlation with inhibition of autophagy and modulation of AMPK/mTOR and JNK pathways

(2014) Zhongshun Guo et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Crocetin, a carotenoid derivative, inhibits retinal ischemic damage in mice

(2013) Fumiya Ishizuka et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis

(2013) Sarah Huntwork-Rodriguez et al.   JOURNAL OF CELL BIOLOGY

Progressive morphological changes and impaired retinal function associated with temporal regulation of gene expression after retinal ischemia/reperfusion injury in mice

(2013) Byung-Jin Kim et al.   Molecular Neurodegeneration

Transplantation with retinal progenitor cells repairs visual function in rats with retinal ischemia–reperfusion injury

(2013) Xueying Li et al.   NEUROSCIENCE LETTERS

DLK initiates a transcriptional program that couples apoptotic and regenerative responses to axonal injury

(2013) T. A. Watkins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death

(2013) D. S. Welsbie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of Endoplasmic Reticulum Stress by Hyperglycemia Is Essential for Muller Cell-Derived Inflammatory Cytokine Production in Diabetes

(2012) Y. Zhong et al.   DIABETES

Neuronal toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro

(2012) Sophie Leow-Dyke et al.   Journal of Neuroinflammation

JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death

(2012) Kimberly A. Fernandes et al.   NEUROBIOLOGY OF DISEASE

Activation of Autophagy in a Rat Model of Retinal Ischemia following High Intraocular Pressure

(2011) Antonio Piras et al.   PLoS One

Mitogen-activated protein kinase phosphatase-1 (MKP-1) in retinal ischemic preconditioning

(2010) John C. Dreixler et al.   EXPERIMENTAL EYE RESEARCH

Microtubule Stabilization by Bone Morphogenetic Protein Receptor-Mediated Scaffolding of c-Jun N-Terminal Kinase Promotes Dendrite Formation

(2010) M. Podkowa et al.   MOLECULAR AND CELLULAR BIOLOGY

Distal axonopathy with structural persistence in glaucomatous neurodegeneration

(2010) S. D. Crish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

c-Jun N-terminal kinase (JNK) signaling: Recent advances and challenges

(2009) Marie A. Bogoyevitch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Morphological changes in the visual pathway induced by experimental glaucoma in Japanese monkeys

(2009) Yasushi Ito et al.   EXPERIMENTAL EYE RESEARCH

MAP Kinase Pathways in Neuronal Cell Death

(2008) Karen Philpott et al.   CNS & Neurological Disorders-Drug Targets

Interleukin-1 Stimulates Glutamate Uptake in Glial Cells by Accelerating Membrane Trafficking of Na+/K+-ATPase via Actin Depolymerization

(2008) K. Namekata et al.   MOLECULAR AND CELLULAR BIOLOGY