Thiamine Deficiency and Neurodegeneration: the Interplay Among Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy

The unfolded protein response in neurodegenerative diseases: a neuropathological perspective

(2015) Wiep Scheper et al.   ACTA NEUROPATHOLOGICA

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

(2015) Sandra I. Mota et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Autophagy: A housekeeper in cardiorenal metabolic health and disease

(2015) Guanghong Jia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Advances in Alzheimer’s Disease Drug Development

(2015) Michael S Rafii et al.   BMC Medicine

Modulation of Endoplasmic Reticulum Stress: An Opportunity to Prevent Neurodegeneration?

(2015) Ana I. Placido et al.   CNS & Neurological Disorders-Drug Targets

Targeting the unfolded protein response for disease intervention

(2015) Alexis Rivas et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Long-Term Treatment with High-Dose Thiamine in Parkinson Disease: An Open-Label Pilot Study

(2015) Antonio Costantini et al.   JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE

Autophagy in Neurodegenerative Diseases: From Mechanism to Therapeutic Approach

(2015) Jihoon Nah et al.   MOLECULES AND CELLS

Oxidative and nitrative stress in neurodegeneration

(2015) Catherine A. Cobb et al.   NEUROBIOLOGY OF DISEASE

Interrelation of Oxidative Stress and Inflammation in Neurodegenerative Disease: Role of TNF

(2015) Roman Fischer et al.   Oxidative Medicine and Cellular Longevity

PKR downregulation prevents neurodegeneration and β-amyloid production in a thiamine-deficient model

(2015) F Mouton-Liger et al.   Cell Death & Disease

Thiamin Deficiency in People with Obesity

(2015) Jennifer C Kerns et al.   Advances in Nutrition

Autophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALS

(2015) Francesca Navone et al.   Cells

Intravenous Infusion of Monocytes Isolated from 2-Week-Old Mice Enhances Clearance of Beta-Amyloid Plaques in an Alzheimer Mouse Model

(2015) Lindsay A. Hohsfield et al.   PLoS One

Béribéri du nourrisson : à propos d’un cas

(2014) P. Moulin et al.   ARCHIVES DE PEDIATRIE

Autophagy and ethanol neurotoxicity

(2014) Jia Luo   Autophagy

Thiamine Deficiency-Mediated Brain Mitochondrial Pathology in Alaskan Huskies with Mutation inSLC19A3.1

(2014) Karen Vernau et al.   BRAIN PATHOLOGY

Rasagiline prevents neurodegeneration in thiamine deficient rats—A longitudinal MRI study

(2014) Vered Dror et al.   BRAIN RESEARCH

Thiamin deficiency and heart failure: the current knowledge and gaps in literature

(2014) Mavra Ahmed et al.   HEART FAILURE REVIEWS

Short Mitochondrial ARF Triggers Parkin/PINK1-dependent Mitophagy

(2014) Karl Grenier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of astrocytes in thiamine deficiency

(2014) Szeifoul Afadlal et al.   METABOLIC BRAIN DISEASE

Thiamine Deficiency: An Update of Pathophysiologic Mechanisms and Future Therapeutic Considerations

(2014) Eman Abdou et al.   NEUROCHEMICAL RESEARCH

Thiamine deficiency induces anorexia by inhibiting hypothalamic AMPK

(2014) M. Liu et al.   NEUROSCIENCE

The worldwide economic impact of dementia 2010

(2013) Anders Wimo et al.   Alzheimers & Dementia

Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers

(2013) Sovan Sarkar   BIOCHEMICAL SOCIETY TRANSACTIONS

Autophagy alleviates neurodegeneration caused by mild impairment of oxidative metabolism

(2013) Ya Meng et al.   JOURNAL OF NEUROCHEMISTRY

Thiamine deficiency induces oxidative stress in brain mitochondria of Mus musculus

(2013) Anupama Sharma et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Folate and thiamine transporters mediated by facilitative carriers (SLC19A1-3 and SLC46A1) and folate receptors

(2013) Rongbao Zhao et al.   MOLECULAR ASPECTS OF MEDICINE

Autophagy in aging and neurodegenerative diseases: implications for pathogenesis and therapy

(2013) Chen-Chen Tan et al.   NEUROBIOLOGY OF AGING

The impact of oxidative stress in thiamine deficiency: A multifactorial targeting issue

(2013) Alan S. Hazell et al.   NEUROCHEMISTRY INTERNATIONAL

Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: Implications for diagnostic and therapeutic strategies

(2013) Zhichun Chen et al.   PROGRESS IN NEUROBIOLOGY

Thiamine Deficiency Induced Neurochemical, Neuroanatomical, and Neuropsychological Alterations: A Reappraisal

(2013) Raffaele Nardone et al.   TheScientificWorldJOURNAL

ER Stress and Effects of DHA as an ER Stress Inhibitor

(2013) Gulnaz Begum et al.   Translational Stroke Research

Role of Thiamine in Alzheimer's Disease

(2012) Khanh vinh quốc Lu’o’ng et al.   American Journal of Alzheimers Disease and Other Dementias

Autophagy is a protective response to ethanol neurotoxicity

(2012) Gang Chen et al.   Autophagy

Cortical signatures of cognition and their relationship to Alzheimer’s disease

(2012) Alden L. Gross et al.   Brain Imaging and Behavior

Thiamine Nutritional Status and Depressive Symptoms Are Inversely Associated among Older Chinese Adults

(2012) Geng Zhang et al.   JOURNAL OF NUTRITION

Abnormal thiamine-dependent processes in Alzheimer's Disease. Lessons from diabetes

(2012) Gary E. Gibson et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Wernicke’s Encephalopathy and Korsakoff’s Syndrome Revisited

(2012) Edith V. Sullivan et al.   NEUROPSYCHOLOGY REVIEW

The Evolution and Treatment of Korsakoff's Syndrome

(2012) A. D. Thomson et al.   NEUROPSYCHOLOGY REVIEW

Role of Endoplasmic Reticulum Stress in Metabolic Disease and Other Disorders

(2011) Lale Ozcan et al.   Annual Review of Medicine

Beyond Alcoholism

(2011) Laurie M. McCormick et al.   Cognitive and Behavioral Neurology

Protein folding stress in neurodegenerative diseases: a glimpse into the ER

(2011) Soledad Matus et al.   CURRENT OPINION IN CELL BIOLOGY

Targeting Mitochondrial Bioenergetics for Alzheimers Prevention and Treatment

(2011) Jia Yao et al.   CURRENT PHARMACEUTICAL DESIGN

Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders

(2011) Karen M. Doyle et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Alcohol-related amnesia and dementia: Animal models have revealed the contributions of different etiological factors on neuropathology, neurochemical dysfunction and cognitive impairment

(2011) Ryan P. Vetreno et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

The Unfolded Protein Response: Integrating Stress Signals Through the Stress Sensor IRE1α

(2011) Claudio Hetz et al.   PHYSIOLOGICAL REVIEWS

Involvement of autophagy in alcoholic liver injury and hepatitis C pathogenesis

(2011) Natalia A Osna   WORLD JOURNAL OF GASTROENTEROLOGY

Brain Glucose Hypometabolism and Oxidative Stress in Preclinical Alzheimer's Disease

(2010) Lisa Mosconi et al.   Annals of the New York Academy of Sciences

Autophagosome Formation and Molecular Mechanism of Autophagy

(2010) Isei Tanida   ANTIOXIDANTS & REDOX SIGNALING

Neuronal MCP-1 Mediates Microglia Recruitment and Neurodegeneration Induced by the Mild Impairment of Oxidative Metabolism

(2010) Guang Yang et al.   BRAIN PATHOLOGY

ADAR2-dependent RNA editing of GluR2 is involved in thiamine deficiency-induced alteration of calcium dynamics

(2010) Shuchen Lee et al.   Molecular Neurodegeneration

Cognition, glucose metabolism and amyloid burden in Alzheimer's disease

(2010) Ansgar J. Furst et al.   NEUROBIOLOGY OF AGING

Modeling neurodegenerative disease pathophysiology in thiamine deficiency: Consequences of impaired oxidative metabolism

(2010) Shivraj S. Jhala et al.   NEUROCHEMISTRY INTERNATIONAL

Signs of Preclinical Wernicke's Encephalopathy and Thiamine Levels as Predictors of Neuropsychological Deficits in Alcoholism without Korsakoff's Syndrome

(2010) Anne-Lise Pitel et al.   NEUROPSYCHOPHARMACOLOGY

The multifaceted therapeutic potential of benfotiamine

(2010) Pitchai Balakumar et al.   PHARMACOLOGICAL RESEARCH

Thiamine Status in Humans and Content of Phosphorylated Thiamine Derivatives in Biopsies and Cultured Cells

(2010) Marjorie Gangolf et al.   PLoS One

Ethanol Promotes Thiamine Deficiency-Induced Neuronal Death: Involvement of Double-Stranded RNA-activated Protein Kinase

(2009) Zun-Ji Ke et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Senescence accelerated mouse strain is sensitive to neurodegeneration induced by mild impairment of oxidative metabolism

(2009) Qipeng Zhang et al.   BRAIN RESEARCH

Targeting ASK1 in ER stress-related neurodegenerative diseases

(2009) Kengo Homma et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Cardiac Beriberi: Often a Missed Diagnosis

(2009) S. N. Rao et al.   JOURNAL OF TROPICAL PEDIATRICS

Thiamine deficiency increases β-secretase activity and accumulation of β-amyloid peptides

(2009) Qipeng Zhang et al.   NEUROBIOLOGY OF AGING

Anthocyanins: Are They Beneficial in Treating Ethanol Neurotoxicity?

(2009) Gang Chen et al.   NEUROTOXICITY RESEARCH

Alcohol Dementia and Thermal Dysregulation: A Case Report and Review of the Literature

(2008) Kaloyan S. Tanev et al.   American Journal of Alzheimers Disease and Other Dementias

Thiamine deficiency induces oxidative stress and exacerbates the plaque pathology in Alzheimer's mouse model

(2008) Saravanan S. Karuppagounder et al.   NEUROBIOLOGY OF AGING

Translocation of Amyloid Precursor Protein C-terminal Fragment(s) to the Nucleus Precedes Neuronal Death due to Thiamine Deficiency-induced Mild Impairment of Oxidative Metabolism

(2008) Saravanan S. Karuppagounder et al.   NEUROCHEMICAL RESEARCH

Characteristics of Thiamin and Its Relevance to the Management of Heart Failure

(2008) Jennifer A. Wooley   NUTRITION IN CLINICAL PRACTICE

A DFT study of solvation effects on the tautomeric equilibrium and catalytic ylide generation of thiamin models

(2007) Mette Alstrup Lie et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY