Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors
出版年份 2023 全文链接
标题
Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors
作者
关键词
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出版物
NATURE IMMUNOLOGY
Volume 24, Issue 8, Pages 1345-1357
出版商
Springer Science and Business Media LLC
发表日期
2023-07-04
DOI
10.1038/s41590-023-01543-9
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Neoantigen-specific CD4+ T cells in human melanoma have diverse differentiation states and correlate with CD8+ T cell, macrophage, and B cell function
- (2022) Joshua R. Veatch et al. CANCER CELL
- Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers
- (2022) Frank J. Lowery et al. SCIENCE
- Potentiating adoptive cell therapy using synthetic IL-9 receptors
- (2022) Anusha Kalbasi et al. NATURE
- Signatures of recent activation identify a circulating T cell compartment containing tumor-specific antigen receptors with high avidity
- (2022) Anna Purcarea et al. Science Immunology
- The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes
- (2022) Qizhao Huang et al. CELL
- Mechanisms of CD40-dependent cDC1 licensing beyond costimulation
- (2022) Renee Wu et al. NATURE IMMUNOLOGY
- Tumor cells fail to present MHC-II–restricted epitopes derived from oncogenes to CD4+ T cells
- (2022) Spencer E. Brightman et al. JCI Insight
- TCR-engineered T cells targeting E7 for patients with metastatic HPV-associated epithelial cancers
- (2021) Nisha B. Nagarsheth et al. NATURE MEDICINE
- Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer
- (2021) Amélie Cachot et al. Science Advances
- A vaccine targeting mutant IDH1 in newly diagnosed glioma
- (2021) Michael Platten et al. NATURE
- Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes
- (2021) Jason M. Schenkel et al. IMMUNITY
- Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma
- (2021) Giacomo Oliveira et al. NATURE
- Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens
- (2020) Parisa Malekzadeh et al. CLINICAL CANCER RESEARCH
- Harnessing neoantigen specific CD4 T cells for cancer immunotherapy
- (2020) Spencer E. Brightman et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Intratumoral CD4+ T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder Cancer
- (2020) David Y. Oh et al. CELL
- cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity
- (2020) Stephen T. Ferris et al. NATURE
- A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer
- (2020) Patrick A. Ott et al. CELL
- Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients
- (2019) Gal Cafri et al. Nature Communications
- Endogenous CD4+ T Cells Recognize Neoantigens in Lung Cancer Patients, Including Recurrent Oncogenic KRAS and ERBB2 (Her2) Driver Mutations
- (2019) Joshua R. Veatch et al. Cancer Immunology Research
- CD4+ T cell-mediated rejection of MHC class II-positive tumor cells is dependent on antigen secretion and indirect presentation on host APCs
- (2018) Ole Audun Werner Haabeth et al. CANCER RESEARCH
- Tumor-infiltrating BRAFV600E-specific CD4+ T cells correlated with complete clinical response in melanoma
- (2018) Joshua R. Veatch et al. JOURNAL OF CLINICAL INVESTIGATION
- MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma
- (2018) Scott J. Rodig et al. Science Translational Medicine
- Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
- (2018) Derin B. Keskin et al. NATURE
- CD4 + T Cell Help Confers a Cytotoxic T Cell Effector Program Including Coinhibitory Receptor Downregulation and Increased Tissue Invasiveness
- (2017) Tomasz Ahrends et al. IMMUNITY
- Treatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II–Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3
- (2017) Yong-Chen Lu et al. JOURNAL OF CLINICAL ONCOLOGY
- An immunogenic personal neoantigen vaccine for patients with melanoma
- (2017) Patrick A. Ott et al. NATURE
- Isolation and Characterization of an HLA-DPB1*04
- (2016) Xin Yao et al. JOURNAL OF IMMUNOTHERAPY
- T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer
- (2016) Eric Tran et al. NEW ENGLAND JOURNAL OF MEDICINE
- IL-7 signaling imparts polyfunctionality and stemness potential to CD4+ T cells
- (2016) Zhi-Chun Ding et al. OncoImmunology
- Mutant MHC class II epitopes drive therapeutic immune responses to cancer
- (2015) Sebastian Kreiter et al. NATURE
- High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma
- (2014) Carsten Linnemann et al. NATURE MEDICINE
- Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma
- (2014) Alexandra Snyder et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer
- (2014) E. Tran et al. SCIENCE
- featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
- (2013) Y. Liao et al. BIOINFORMATICS
- Single Naive CD4+ T Cells from a Diverse Repertoire Produce Different Effector Cell Types during Infection
- (2013) Noah J. Tubo et al. CELL
- Sustained Interactions between T Cell Receptors and Antigens Promote the Differentiation of CD4+ Memory T Cells
- (2013) Chulwoo Kim et al. IMMUNITY
- T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapy
- (2013) S. Zhong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors
- (2012) N. Cieri et al. BLOOD
- Quality control and preprocessing of metagenomic datasets
- (2011) R. Schmieder et al. BIOINFORMATICS
- High prevalence of low affinity peptide–MHC II tetramer–negative effectors during polyclonal CD4+T cell responses
- (2011) Joseph J. Sabatino et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype
- (2010) Z.-C. Ding et al. BLOOD
- CD4+ T-Cell Help in the Tumor Milieu Is Required for Recruitment and Cytolytic Function of CD8+ T Lymphocytes
- (2010) R. Bos et al. CANCER RESEARCH
- Tumor-reactive CD4+T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
- (2010) Sergio A. Quezada et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Recovery from Cyclophosphamide-Induced Lymphopenia Results in Expansion of Immature Dendritic Cells Which Can Mediate Enhanced Prime-Boost Vaccination Antitumor Responses In Vivo When Stimulated with the TLR3 Agonist Poly(I:C)
- (2009) M. L. Salem et al. JOURNAL OF IMMUNOLOGY
- Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells
- (2009) Luca Gattinoni et al. NATURE MEDICINE
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