A discrete ‘early-responder’ stromal-cell subtype orchestrates immunocyte recruitment to injured tissue

IL-17A–producing γδT cells promote muscle regeneration in a microbiota-dependent manner

(2022) Alexander O. Mann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Thymic epithelial cells co-opt lineage-defining transcription factors to eliminate autoreactive T cells

(2022) Daniel A. Michelson et al.   CELL

Injury-mediated stiffening persistently activates muscle stem cells through YAP and TAZ mechanotransduction

(2021) Jason S. Silver et al.   Science Advances

Fibroblast-macrophage reciprocal interactions in health, fibrosis, and cancer

(2021) Matthew B. Buechler et al.   IMMUNITY

Cross-tissue organization of the fibroblast lineage

(2021) Matthew B. Buechler et al.   NATURE

Integrated analysis of multimodal single-cell data

(2021) Yuhan Hao et al.   CELL

Skeletal muscle regeneration with robotic actuation–mediated clearance of neutrophils

(2021) Bo Ri Seo et al.   Science Translational Medicine

Neuronal, stromal, and T-regulatory cell crosstalk in murine skeletal muscle

(2020) Kathy Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic Interstitial Cell Response during Myocardial Infarction Predicts Resilience to Rupture in Genetically Diverse Mice

(2020) Elvira Forte et al.   Cell Reports

Adipogenesis of skeletal muscle fibro/adipogenic progenitors is affected by the WNT5a/GSK3/β-catenin axis

(2020) Alessio Reggio et al.   CELL DEATH AND DIFFERENTIATION

Single-Cell Analysis of the Muscle Stem Cell Hierarchy Identifies Heterotypic Communication Signals Involved in Skeletal Muscle Regeneration

(2020) Andrea J. De Micheli et al.   Cell Reports

Inhibition of inflammatory CCR2 signaling promotes aged muscle regeneration and strength recovery after injury

(2020) Roméo S. Blanc et al.   Nature Communications

Mesenchymal Bmp3b expression maintains skeletal muscle integrity and decreases in age-related sarcopenia

(2020) Akiyoshi Uezumi et al.   JOURNAL OF CLINICAL INVESTIGATION

Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors

(2019) Laura Lukjanenko et al.   Cell Stem Cell

Distinct fibroblast subsets drive inflammation and damage in arthritis

(2019) Adam P. Croft et al.   NATURE

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

(2019) Fan Zhang et al.   NATURE IMMUNOLOGY

Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle

(2019) Michael N. Wosczyna et al.   Cell Reports

Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B

(2019) Marshall W. Hogarth et al.   Nature Communications

Single-cell RNA sequencing reveals stromal evolution into LRRC15+ myofibroblasts as a determinant of patient response to cancer immunotherapy

(2019) Claudia X Dominguez et al.   Cancer Discovery

Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle Regeneration

(2019) R. Wilder Scott et al.   Cell Stem Cell

Tregcells limit IFN-γ production to control macrophage accrual and phenotype during skeletal muscle regeneration

(2018) Marisella Panduro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease

(2018) James Kinchen et al.   CELL

Simultaneous epitope and transcriptome measurement in single cells

(2017) Marlon Stoeckius et al.   NATURE METHODS

Connective tissue cells expressing fibro/adipogenic progenitor markers increase under chronic damage: relevance in fibroblast-myofibroblast differentiation and skeletal muscle fibrosis

(2016) Osvaldo Contreras et al.   CELL AND TISSUE RESEARCH

PDGFRα signalling promotes fibrogenic responses in collagen-producing cells in Duchenne muscular dystrophy

(2016) Nicholas Ieronimakis et al.   JOURNAL OF PATHOLOGY

Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells

(2016) Sylvia Heink et al.   NATURE IMMUNOLOGY

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Pharmacological blockage of fibro/adipogenic progenitor expansion and suppression of regenerative fibrogenesis is associated with impaired skeletal muscle regeneration

(2016) Daniela Fiore et al.   Stem Cell Research

Monocyte/Macrophage-derived IGF-1 Orchestrates Murine Skeletal Muscle Regeneration and Modulates Autocrine Polarization

(2015) Joanne Tonkin et al.   MOLECULAR THERAPY

Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors

(2015) Dario R Lemos et al.   NATURE MEDICINE

Isolation of skeletal muscle stem cells by fluorescence-activated cell sorting

(2015) Ling Liu et al.   Nature Protocols

In vivo Monitoring of Transcriptional Dynamics After Lower-Limb Muscle Injury Enables Quantitative Classification of Healing

(2015) Carlos A. Aguilar et al.   Scientific Reports

FOXP3+ T Cells Recruited to Sites of Sterile Skeletal Muscle Injury Regulate the Fate of Satellite Cells and Guide Effective Tissue Regeneration

(2015) Alessandra Castiglioni et al.   PLoS One

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

A Special Population of Regulatory T Cells Potentiates Muscle Repair

(2013) Dalia Burzyn et al.   CELL

Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice

(2013) Chiara Mozzetta et al.   EMBO Molecular Medicine

Intestinal monocytes and macrophages are required for T cell polarization in response toCitrobacter rodentium

(2013) Heidi A. Schreiber et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Smart-seq2 for sensitive full-length transcriptome profiling in single cells

(2013) Simone Picelli et al.   NATURE METHODS

Osteogenic Differentiation Capacity of Human Skeletal Muscle-Derived Progenitor Cells

(2013) Teruyo Oishi et al.   PLoS One

Pax7 is critical for the normal function of satellite cells in adult skeletal muscle

(2013) J. von Maltzahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification

(2012) Michael N Wosczyna et al.   JOURNAL OF BONE AND MINERAL RESEARCH

IL-10 Triggers Changes in Macrophage Phenotype That Promote Muscle Growth and Regeneration

(2012) B. Deng et al.   JOURNAL OF IMMUNOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Differentially Activated Macrophages Orchestrate Myogenic Precursor Cell Fate During Human Skeletal Muscle Regeneration

(2012) Marielle Saclier et al.   STEM CELLS

Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration

(2011) M. M. Murphy et al.   DEVELOPMENT

Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration

(2011) R. Sambasivan et al.   DEVELOPMENT

An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration

(2011) C. Lepper et al.   DEVELOPMENT

Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle

(2011) A. Uezumi et al.   JOURNAL OF CELL SCIENCE

Regulation of skeletal muscle regeneration by CCR2-activating chemokines is directly related to macrophage recruitment

(2010) Carlo O. Martinez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

A transitional extracellular matrix instructs cell behavior during muscle regeneration

(2010) Sarah Calve et al.   DEVELOPMENTAL BIOLOGY

CXCL5 Regulates Chemokine Scavenging and Pulmonary Host Defense to Bacterial Infection

(2010) Junjie Mei et al.   IMMUNITY

Syndecan-3 and Notch cooperate in regulating adult myogenesis

(2010) Addolorata Pisconti et al.   JOURNAL OF CELL BIOLOGY

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

(2010) Akiyoshi Uezumi et al.   NATURE CELL BIOLOGY

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

(2010) Aaron W. B. Joe et al.   NATURE CELL BIOLOGY

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

Muscle resident macrophages control the immune cell reaction in a mouse model of notexin-induced myoinjury

(2009) Madly Brigitte et al.   ARTHRITIS AND RHEUMATISM

Self-renewal and expansion of single transplanted muscle stem cells

(2008) Alessandra Sacco et al.   NATURE

Monitoring cellular movement in vivo with photoconvertible fluorescence protein "Kaede" transgenic mice

(2008) M. Tomura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA