Targeting proprotein convertases in furin-rich lung cancer cells results in decreased in vitro and in vivo growth

Identification of potent and compartment-selective small molecule furin inhibitors using cell-based assays

(2015) Bruno Ramos-Molina et al.   BIOCHEMICAL PHARMACOLOGY

Novel Furin Inhibitors with Potent Anti-infectious Activity

(2015) Kornelia Hardes et al.   ChemMedChem

Therapeutic uses of furin and its inhibitors: a patent review

(2015) Frédéric Couture et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Pilot Trial of FANG Immunotherapy in Ewing's Sarcoma

(2015) Maurizio Ghisoli et al.   MOLECULAR THERAPY

Proprotein Convertase Inhibition Results in Decreased Ski Proliferation, Tumorigenesis, and Metastasis

(2015) Daniel E. Bassi et al.   NEOPLASIA

Summary of bi-shRNAfurin/GM-CSF Augmented Autologous Tumor Cell Immunotherapy (FANG™) in Advanced Cancer of the Liver

(2014) John Nemunaitis et al.   ONCOLOGY

Regulation of TGFβ and related signals by precursor processing

(2014) Daniel B. Constam   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Molecular Validation of PACE4 as a Target in Prostate Cancer

(2014) François D'Anjou et al.   Translational Oncology

The Multifaceted Proprotein Convertases: Their Unique, Redundant, Complementary, and Opposite Functions

(2013) Nabil G. Seidah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alterations in Gene Expression of Proprotein Convertases in Human Lung Cancer Have a Limited Number of Scenarios

(2013) Ilya V. Demidyuk et al.   PLoS One

Phase I Trial of “bi-shRNAifurin/GMCSF DNA/Autologous Tumor Cell” Vaccine (FANG) in Advanced Cancer

(2011) Neil Senzer et al.   MOLECULAR THERAPY

Inhibition of the Proprotein Convertases Represses the Invasiveness of Human Primary Melanoma Cells with Altered p53, CDKN2A and N-Ras Genes

(2010) Claude Lalou et al.   PLoS One

A Novel Enediynyl Peptide Inhibitor of Furin That Blocks Processing of proPDGF-A, B and proVEGF-C

(2009) Ajoy Basak et al.   PLoS One

Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells

(2008) Nathalie Scamuffa et al.   JOURNAL OF CLINICAL INVESTIGATION