Triazole RGD antagonist reverts TGFβ1-induced endothelial-to-mesenchymal transition in endothelial precursor cells

Radiosynthesis and micro-SPECT analysis of triazole-based RGD integrin ligands as non-peptide molecular imaging probes for angiogenesis

(2015) Francesca Bianchini et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The Effect of Bevacizumab on Human Malignant Melanoma Cells with Functional VEGF/VEGFR2 Autocrine and Intracrine Signaling Loops

(2015) Una Adamcic et al.   NEOPLASIA

Angiopoietin-like 7, a novel pro-angiogenetic factor over-expressed in cancer

(2014) Matteo Parri et al.   ANGIOGENESIS

Role of Side-Chain Bioisosteres in Determining the Binding Affinity of Click Chemistry Derived RGD Peptidomimetics to αvβ3Integrin

(2014) Pierangelo Fabbrizzi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Cilengitide downmodulates invasiveness and vasculogenic mimicry of neuropilin 1 expressing melanoma cells through the inhibition of αvβ5 integrin

(2014) Federica Ruffini et al.   INTERNATIONAL JOURNAL OF CANCER

Narrative Review: Fibrotic Diseases: Cellular and Molecular Mechanisms and Novel Therapies

(2013) Joel Rosenbloom   ANNALS OF INTERNAL MEDICINE

Cell Trafficking of Endothelial Progenitor Cells in Tumor Progression

(2013) P. de la Puente et al.   CLINICAL CANCER RESEARCH

It has to be the αv: myofibroblast integrins activate latent TGF-β1

(2013) Boris Hinz   NATURE MEDICINE

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs

(2013) Neil C Henderson et al.   NATURE MEDICINE

Integrin-mediated regulation of TGFβ in fibrosis

(2012) Neil C. Henderson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Strategies for anti-fibrotic therapies

(2012) Joel Rosenbloom et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The role of endothelial-mesenchymal transition in development and pathological process

(2012) Feng Lin et al.   IUBMB LIFE

Crystal structure of α5β1 integrin ectodomain: Atomic details of the fibronectin receptor

(2012) Masamichi Nagae et al.   JOURNAL OF CELL BIOLOGY

The myofibroblast matrix: implications for tissue repair and fibrosis

(2012) Franco Klingberg et al.   JOURNAL OF PATHOLOGY

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

Role of Endothelial-Mesenchymal Transition (EndoMT) in the Pathogenesis of Fibrotic Disorders

(2011) Sonsoles Piera-Velazquez et al.   AMERICAN JOURNAL OF PATHOLOGY

Endothelial progenitor cell-dependent angiogenesis requires localization of the full-length form of uPAR in caveolae

(2011) F. Margheri et al.   BLOOD

Java web tools for PCR, in silico PCR, and oligonucleotide assembly and analysis

(2011) Ruslan Kalendar et al.   GENOMICS

α6-Integrin Subunit Plays a Major Role in the Proangiogenic Properties of Endothelial Progenitor Cells

(2010) Claire Bouvard et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Integrin–TGF-β crosstalk in fibrosis, cancer and wound healing

(2010) Coert Margadant et al.   EMBO REPORTS

Click-Chemistry-Derived Triazole Ligands of Arginine−Glycine−Aspartate (RGD) Integrins with a Broad Capacity To Inhibit Adhesion of Melanoma Cells and Both in Vitro and in Vivo Angiogenesis

(2010) Andrea Trabocchi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Failure of bevacizumab in early-stage colon cancer

(2010) Daniel J. Sargent   Nature Reviews Clinical Oncology

TGFβ: a sleeping giant awoken by integrins

(2010) John J. Worthington et al.   TRENDS IN BIOCHEMICAL SCIENCES

TGF-β and fibrosis in different organs — molecular pathway imprints

(2009) Dirk Pohlers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Enhanced dermal wound neovascularization by targeted delivery of endothelial progenitor cells using an RGD-g-PLLA scaffold

(2009) Koung Li Kim et al.   BIOMATERIALS

Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors

(2009) Andrew R Reynolds et al.   NATURE MEDICINE

New regulatory mechanisms of TGF-β receptor function

(2009) Jong Seok Kang et al.   TRENDS IN CELL BIOLOGY

Signaling cross-talk between TGF-β/BMP and other pathways

(2008) Xing Guo et al.   CELL RESEARCH

Transforming Growth Factor β1 Induces αvβ3 Integrin Expression in Human Lung Fibroblasts via a β3 Integrin-, c-Src-, and p38 MAPK-dependent Pathway

(2008) Dmitri V. Pechkovsky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY