Dynamics and Composition of Small Heat Shock Protein Condensates and Aggregates

Bidirectional protein–protein interactions control liquid–liquid phase separation of PSD-95 and its interaction partners

(2022) Nikolaj Riis Christensen et al.   iScience

Insights on Human Small Heat Shock Proteins and Their Alterations in Diseases

(2022) B. Tedesco et al.   Frontiers in Molecular Biosciences

Engineering of ultraID, a compact and hyperactive enzyme for proximity-dependent biotinylation in living cells

(2022) Lea Kubitz et al.   Communications Biology

Charge-driven condensation of RNA and proteins suggests broad role of phase separation in cytoplasmic environments

(2021) Bercem Dutagaci et al.   eLife

Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing

(2021) Simon Alberti et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome

(2021) Edward L. Huttlin et al.   CELL

Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor

(2021) Tatiana Tiago et al.   Cell Death & Disease

IUPred3: prediction of protein disorder enhanced with unambiguous experimental annotation and visualization of evolutionary conservation

(2021) Gábor Erdős et al.   NUCLEIC ACIDS RESEARCH

The chaperone HSPB1 prepares protein aggregates for resolubilization by HSP70

(2021) Conrado C. Gonçalves et al.   Scientific Reports

SciPy 1.0: fundamental algorithms for scientific computing in Python

(2020) Pauli Virtanen et al.   NATURE METHODS

Structural aspects of the human small heat shock proteins related to their functional activities

(2020) Wilbert C. Boelens   CELL STRESS & CHAPERONES

Composition-dependent thermodynamics of intracellular phase separation

(2020) Joshua A. Riback et al.   NATURE

The Gene Ontology resource: enriching a GOld mine

(2020) et al.   NUCLEIC ACIDS RESEARCH

Mechanisms of Small Heat Shock Proteins

(2019) Maria K. Janowska et al.   Cold Spring Harbor Perspectives in Biology

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

(2019) Simon Alberti et al.   CELL

Regulation of small heat shock proteins by hetero-oligomer formation

(2019) Evgeny V. Mymrikov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disorder Atlas: Web-based software for the proteome-based interpretation of intrinsic disorder predictions

(2019) Michael Vincent et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Terminal regions confer plasticity to the tetrameric assembly of human HspB2 and HspB3

(2018) Alice R. Clark et al.   JOURNAL OF MOLECULAR BIOLOGY

Cellular Handling of Protein Aggregates by Disaggregation Machines

(2018) Axel Mogk et al.   MOLECULAR CELL

Small heat shock proteins: Simplicity meets complexity

(2018) Martin Haslbeck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools

(2018) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Compositional adaptability in NPM1-SURF6 scaffolding networks enabled by dynamic switching of phase separation mechanisms

(2018) Mylene C. Ferrolino et al.   Nature Communications

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The human protein atlas: A spatial map of the human proteome

(2017) Peter J. Thul et al.   PROTEIN SCIENCE

Intrinsically Disordered Proteome of Human Membrane-Less Organelles

(2017) April L. Darling et al.   PROTEOMICS

Liquid phase condensation in cell physiology and disease

(2017) Yongdae Shin et al.   SCIENCE

Aberrant Compartment Formation by HSPB2 Mislocalizes Lamin A and Compromises Nuclear Integrity and Function

(2017) Federica F. Morelli et al.   Cell Reports

Granulostasis: Protein Quality Control of RNP Granules

(2017) Simon Alberti et al.   Frontiers in Molecular Neuroscience

Protein misfolding in neurodegenerative diseases: implications and strategies

(2017) Patrick Sweeney et al.   Translational Neurodegeneration

The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins

(2016) Evgeny V. Mymrikov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Spatially resolved proteomic mapping in living cells with the engineered peroxidase APEX2

(2016) Victoria Hung et al.   Nature Protocols

Proteome- pI : proteome isoelectric point database

(2016) Lukasz P. Kozlowski   NUCLEIC ACIDS RESEARCH

A collection of intrinsic disorder characterizations from eukaryotic proteomes

(2016) Michael Vincent et al.   Scientific Data

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Intrinsically disordered proteins in cellular signalling and regulation

(2015) Peter E. Wright et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rescue of αB Crystallin (HSPB5) Mutants Associated Protein Aggregation by Co-Expression of HSPB5 Partners

(2015) Rasha M. Hussein et al.   PLoS One

Liquid-Liquid Phase Separation in Biology

(2014) Anthony A. Hyman et al.   Annual Review of Cell and Developmental Biology

HSPA1A-Independent Suppression of PARK2 C289G Protein Aggregation by Human Small Heat Shock Proteins

(2014) M. Minoia et al.   MOLECULAR AND CELLULAR BIOLOGY

scikit-image: image processing in Python

(2014) Stéfan van der Walt et al.   PeerJ

β-Catenin is O-GlcNAc glycosylated at Serine 23: Implications for β-catenin's subcellular localization and transactivator function

(2013) Jacqueline R. Ha et al.   EXPERIMENTAL CELL RESEARCH

p62 expression and autophagy in αB-crystallin R120G mutant knock-in mouse model of hereditary cataract

(2013) Jonathan A. Wignes et al.   EXPERIMENTAL EYE RESEARCH

Structural and Functional Aspects of Hetero-oligomers Formed by the Small Heat Shock Proteins αB-Crystallin and HSP27

(2013) J. Andrew Aquilina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomic Mapping of Mitochondria in Living Cells via Spatially Restricted Enzymatic Tagging

(2013) H.-W. Rhee et al.   SCIENCE

The Role of Intrinsically Disordered Regions in the Structure and Functioning of Small Heat Shock Proteins

(2012) Maria V. Sudnitsyna et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

The family of mammalian small heat shock proteins (HSPBs): Implications in protein deposit diseases and motor neuropathies

(2012) Alessandra Boncoraglio et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The small heat shock proteins family: The long forgotten chaperones

(2012) C. Garrido et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Comparative Proteomic Analysis of Eleven Common Cell Lines Reveals Ubiquitous but Varying Expression of Most Proteins

(2012) Tamar Geiger et al.   MOLECULAR & CELLULAR PROTEOMICS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

HspB2/Myotonic Dystrophy Protein Kinase Binding Protein (MKBP) as a Novel Molecular Chaperone: Structural and Functional Aspects

(2012) Sankaralingam Prabhu et al.   PLoS One

Structural and functional specificity of small heat shock protein HspB1 and HspB4, two cellular partners of HspB5: Role of the in vitro hetero-complex formation in chaperone activity

(2011) Fériel Skouri-Panet et al.   BIOCHIMIE

p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy

(2010) Terje Høyvarde Clausen et al.   Autophagy

Independent evolution of the core domain and its flanking sequences in small heat shock proteins

(2010) Thomas Kriehuber et al.   FASEB JOURNAL

Selective degradation of aggregate-prone CryAB mutants by HSPB1 is mediated by ubiquitin–proteasome pathways

(2010) Huali Zhang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nuclear Lamins

(2010) T. Dechat et al.   Cold Spring Harbor Perspectives in Biology

HSPB7 is a SC35 speckle resident small heat shock protein

(2009) Michel J. Vos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Small Heat-Shock Proteins HSPB2 and HSPB3 Form Well-defined Heterooligomers in a Unique 3 to 1 Subunit Ratio

(2009) John den Engelsman et al.   JOURNAL OF MOLECULAR BIOLOGY

Significance of α-crystallin heteropolymer with a 3:1 αA/αB ratio: chaperone-like activity, structure and hydrophobicity

(2008) P. N. B. S. Srinivas et al.   BIOCHEMICAL JOURNAL

Intrinsic disorder explains diverse nuclear roles of chromatin remodeling proteins

(2008) Kuljeet Singh Sandhu   JOURNAL OF MOLECULAR RECOGNITION

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY