Early innate role for CD8αα+ cells in tuberculosis

Airway T cells are a correlate of i.v. Bacille Calmette-Guerin-mediated protection against tuberculosis in rhesus macaques

(2023) Patricia A. Darrah et al.   Cell Host & Microbe

Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage

(2023) Lore Billiet et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD8+ lymphocytes are critical for early control of tuberculosis in macaques

(2023) Caylin G. Winchell et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Trimodal single-cell profiling reveals a novel pediatric CD8αα+ T cell subset and broad age-related molecular reprogramming across the T cell compartment

(2023) Zachary Thomson et al.   NATURE IMMUNOLOGY

Key advances in vaccine development for tuberculosis—success and challenges

(2023) Rocky Lai et al.   npj Vaccines

Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control

(2022) Hannah P. Gideon et al.   IMMUNITY

Functional inactivation of pulmonary MAIT cells following 5-OP-RU treatment of non-human primates

(2021) Shunsuke Sakai et al.   Mucosal Immunology

Limited recognition of Mycobacterium tuberculosis-infected macrophages by polyclonal CD4 and CD8 T cells from the lungs of infected mice

(2019) Yash R. Patankar et al.   Mucosal Immunology

Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis

(2017) Constance J. Martin et al.   mBio

Comprehensive definition of human immunodominant CD8 antigens in tuberculosis

(2017) Deborah A. Lewinsohn et al.   npj Vaccines

Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques

(2011) T. A. Waldmann et al.   BLOOD

IL-15 administered by continuous infusion to rhesus macaques induces massive expansion of CD8+ T effector memory population in peripheral blood

(2011) M. C. Sneller et al.   BLOOD

Profound CD4+/CCR5+T cell expansion is induced by CD8+lymphocyte depletion but does not account for accelerated SIV pathogenesis

(2009) Afam Okoye et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Critical Role for CD8 T Cells in a Nonhuman Primate Model of Tuberculosis

(2009) Crystal Y. Chen et al.   PLoS Pathogens