Schwann cell–derived extracellular vesicles as a potential therapy for retinal ganglion cell degeneration

Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury

(2023) Jie Ren et al.   Cell Death & Disease

TNF-α stimulation enhances the neuroprotective effects of gingival MSCs derived exosomes in retinal ischemia-reperfusion injury via the MEG3/miR-21a-5p axis

(2022) Ziyu Yu et al.   BIOMATERIALS

Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells

(2022) Feng Tian et al.   NEURON

Human repair‐related Schwann cells adopt functions of antigen‐presenting cells in vitro

(2022) Jakob Berner et al.   GLIA

Nebulization of extracellular vesicles: A promising small RNA delivery approach for lung diseases

(2022) Yohan Han et al.   JOURNAL OF CONTROLLED RELEASE

Exosomal miR-23b from bone marrow mesenchymal stem cells alleviates oxidative stress and pyroptosis after intracerebral hemorrhage

(2022) Yu-Hua Fan et al.   Neural Regeneration Research

Schwann cell remyelination of the central nervous system: why does it happen and what are the benefits?

(2021) Civia Z. Chen et al.   Open Biology

Preservation of vision after CaMKII-mediated protection of retinal ganglion cells

(2021) Xinzheng Guo et al.   CELL

Increasing toll-like receptor 2 on astrocytes induced by Schwann cell-derived exosomes promotes recovery by inhibiting CSPGs deposition after spinal cord injury

(2021) Dayu Pan et al.   Journal of Neuroinflammation

MicroRNAs are minor constituents of extracellular vesicles that are rarely delivered to target cells

(2021) Manuel Albanese et al.   PLoS Genetics

The biology, function, and biomedical applications of exosomes

(2020) Raghu Kalluri et al.   SCIENCE

Longitudinal Morphological and Functional Assessment of RGC Neurodegeneration After Optic Nerve Crush in Mouse

(2020) Liang Li et al.   Frontiers in Cellular Neuroscience

Strategies to Promote Long-Distance Optic Nerve Regeneration

(2020) Shu-Guang Yang et al.   Frontiers in Cellular Neuroscience

Extracellular vesicles derived from human ES-MSCs protect retinal ganglion cells and preserve retinal function in a rodent model of optic nerve injury

(2020) Seyedeh-Zahra Seyedrazizadeh et al.   Stem Cell Research & Therapy

Retinal Ganglion Cell Survival and Axon Regeneration after Optic Nerve Transection is Driven by Cellular Intravitreal Sciatic Nerve Grafts

(2020) Zubair Ahmed et al.   Cells

Viral delivery of multiple miRNAs promotes retinal ganglion cell survival and functional preservation after optic nerve crush injury

(2020) Ben Mead et al.   EXPERIMENTAL EYE RESEARCH

Exosomes derived from microglia exposed to elevated pressure amplify the neuroinflammatory response in retinal cells

(2020) Inês Dinis Aires et al.   GLIA

MicroRNA-124 Overexpression in Schwann Cells Promotes Schwann Cell-Astrocyte Integration and Inhibits Glial Scar Formation Ability

(2020) Zhijun Li et al.   Frontiers in Cellular Neuroscience

A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells

(2020) Giang N. Nguyen et al.   NATURE BIOTECHNOLOGY

Repair Schwann cell update: Adaptive reprogramming, EMT, and stemness in regenerating nerves

(2019) Kristjan R Jessen et al.   GLIA

UMSC-derived exosomes promote retinal ganglion cells survival in a rat model of optic nerve crush

(2019) Dongyan Pan et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Mesenchymal stem cell-derived extracellular vesicles and retinal ischemia-reperfusion

(2019) Biji Mathew et al.   BIOMATERIALS

Exosomal miRNAs in central nervous system diseases: biomarkers, pathological mediators, protective factors and therapeutic agents

(2019) Xiaohuan Xia et al.   PROGRESS IN NEUROBIOLOGY

TNFα and IL-1β modify the miRNA cargo of astrocyte shed extracellular vesicles to regulate neurotrophic signaling in neurons

(2018) Amrita Datta Chaudhuri et al.   Cell Death & Disease

Release of astroglial vimentin by extracellular vesicles: Modulation of binding and internalization of C3 transferase in astrocytes and neurons

(2018) Andrej Adolf et al.   GLIA

PR1P ameliorates neurodegeneration through activation of VEGF signaling pathway and remodeling of the extracellular environment

(2018) Zai-Long Chi et al.   NEUROPHARMACOLOGY

Extracellular vesicles: Novel promising delivery systems for therapy of brain diseases

(2017) David Rufino-Ramos et al.   JOURNAL OF CONTROLLED RELEASE

Cell transplantation therapy for spinal cord injury

(2017) Peggy Assinck et al.   NATURE NEUROSCIENCE

Bone Marrow-Derived Mesenchymal Stem Cells-Derived Exosomes Promote Survival of Retinal Ganglion Cells Through miRNA-Dependent Mechanisms

(2017) Ben Mead et al.   Stem Cells Translational Medicine

Restoration of Visual Function by Enhancing Conduction in Regenerated Axons

(2016) Fengfeng Bei et al.   CELL

Long non-coding RNA MALAT1 regulates retinal neurodegeneration through CREB signaling

(2016) J. Yao et al.   EMBO Molecular Medicine

Neural activity promotes long-distance, target-specific regeneration of adult retinal axons

(2016) Jung-Hwan A Lim et al.   NATURE NEUROSCIENCE

Glia–neuron interactions in the mammalian retina

(2016) Elena Vecino et al.   PROGRESS IN RETINAL AND EYE RESEARCH

New insights on schwann cell development

(2015) Kelly R. Monk et al.   GLIA

Molecular Mechanisms Mediating Retinal Reactive Gliosis Following Bone Marrow Mesenchymal Stem Cell Transplantation

(2015) Alessia Tassoni et al.   STEM CELLS

Astrocyte-neuron crosstalk regulates the expression and subcellular localization of carbohydrate metabolism enzymes

(2014) Piotr Mamczur et al.   GLIA

Direct optic nerve sheath (DONS) application of Schwann cells prolongs retinal ganglion cell survival in vivo

(2014) L Guo et al.   Cell Death & Disease

Schwann cell-derived exosomes enhance axonal regeneration in the peripheral nervous system

(2013) María Alejandra Lopez-Verrilli et al.   GLIA

The Role of the Transcription Factor CREB in Immune Function

(2010) A. Y. Wen et al.   JOURNAL OF IMMUNOLOGY

An improved method for isolating Schwann cells from postnatal rat sciatic nerves

(2009) Yujun Wei et al.   CELL AND TISSUE RESEARCH

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

Regulation of Schwann cell function by the extracellular matrix

(2008) Michael A. Chernousov et al.   GLIA