Progress and developments in the turbo Grignard reagent i-PrMgCl·LiCl: a ten-year journey

Advances in LiCl-Promoted Preparation of Polyfunctional Grignard Reagents and the Applications

(2015) Yuyan Liu et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

Transition-Metal-Free BF3-Mediated Oxidative and Non-Oxidative Cross-Coupling of Pyridines

(2014) Quan Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Continuous-Flow Synthesis of Functionalized Phenols by Aerobic Oxidation of Grignard Reagents

(2014) Zhi He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Strategies for the modulation of phase II metabolism in a series of PKCε inhibitors

(2014) Jeremy J. Clemens et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Palladium-Catalyzed α-Arylation of Carboxylic Acid Derivatives with Grignard Reagent

(2014) Daiki Tanaka et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Efficient Synthesis and Versatile Reactivity of Porphyrinyl Grignard Reagents

(2014) Keisuke Fujimoto et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Strategies To Prepare and Use Functionalized Organometallic Reagents

(2014) Thomas Klatt et al.   JOURNAL OF ORGANIC CHEMISTRY

Fast and Highly Chemoselective Alkynylation of Thiols with Hypervalent Iodine Reagents Enabled through a Low Energy Barrier Concerted Mechanism

(2014) Reto Frei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Reaction of Grignard Reagents with Bunte Salts: A Thiol-Free Synthesis of Sulfides

(2014) Jonathan T. Reeves et al.   ORGANIC LETTERS

Synthesis and properties of hydrophilic–hydrophobic diblock copolymer ionomers based on poly(p-phenylene)s

(2014) Y. Takeoka et al.   Polymer Chemistry

Synthesis of functionalized α-trifluoroethyl amine scaffolds via Grignard addition to N-aryl hemiaminal ethers

(2014) Amrei Deutsch et al.   RSC Advances

Synthesis and applications of 1-iodo-4-MgCl-1,3-dienes and 1-iodovinyl phenylmagnesium chlorides

(2014) Junnian Wei et al.   Organic Chemistry Frontiers

Full Functionalization of the 7-Azaindole Scaffold by Selective Metalation and Sulfoxide/Magnesium Exchange

(2013) Nadja M. Barl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Full Functionalization of the Imidazole Scaffold by Selective Metalation and Sulfoxide/Magnesium Exchange

(2013) Christoph Sämann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Calix[4]arenes with intramolecularly bridged meta positions prepared via Pd-catalysed double C–H activation

(2013) Jan Holub et al.   CHEMICAL COMMUNICATIONS

Bimetallic Combinations for Dehalogenative Metalation Involving Organic Compounds

(2013) David Tilly et al.   CHEMICAL REVIEWS

Mixed AggregAte (MAA): A Single Concept for All Dipolar Organometallic Aggregates. 2. Syntheses and Reactivities of Homo/HeteroMAAs

(2013) Florence Mongin et al.   CHEMICAL REVIEWS

Quinonediimine-Induced Oxidative Coupling of Organomagnesium Reagents

(2013) Toru Amaya et al.   CHEMISTRY-A EUROPEAN JOURNAL

Mechanism of Copper(I)-Catalyzed Allylic Alkylation of Phosphorothioate Esters: Influence of the Leaving Group on α Regioselectivity

(2013) Wenhao Sheng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Comparative performance evaluation and systematic screening of solvents in a range of Grignard reactions

(2013) Asha Kadam et al.   GREEN CHEMISTRY

The Halogen/Magnesium-Exchange Using iPrMgCl·LiCl and Related Exchange Reagents

(2013) Paul Knochel et al.   HETEROCYCLES

Synthesis and Biological Evaluation of 8-Aminomethyltetracycline Derivatives as Novel Antibacterial Agents

(2013) Roger B. Clark et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fine-Tuning the Oxidative Ability of Persistent Radicals: Electrochemical and Computational Studies of Substituted 2-Pyridylhydroxylamines

(2013) Justin A. Bogart et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Cross-Coupling of Aziridinylmetal Species, Generated by Sulfinyl–Magnesium Exchange, with Aryl Bromides: Reaction Optimization, Scope, and Kinetic Investigations

(2013) Matthew Hughes et al.   JOURNAL OF ORGANIC CHEMISTRY

Transition-Metal-Free BF3-Mediated Regioselective Direct Alkylation and Arylation of Functionalized Pyridines Using Grignard or Organozinc Reagents

(2013) Quan Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Chromium(II)-Catalyzed Cross-Coupling Reactions between Csp2 Centers

(2013) Andreas K. Steib et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of End-Group Functionalized P3HT: General Protocol for P3HT/Nanoparticle Hybrids

(2013) Frederic Monnaie et al.   MACROMOLECULES

Approaches to the synthesis of a novel, anti-HIV active integrase inhibitor

(2013) Maurice Okello et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Development of Quinoline-Based Disruptors of Biofilm Formation Against Vibrio cholerae

(2013) Brian León et al.   ORGANIC LETTERS

Imidazolium-substituted ionic (co)polythiophenes: Compositional influence on solution behavior and thermal properties

(2013) Toon Ghoos et al.   POLYMER

Base-pair recognition ability of hydroxyphenyl nucleobases in parallel triplex DNA

(2013) Yoshiyuki Hari et al.   TETRAHEDRON

Generation of 3-borylbenzynes, their regioselective Diels–Alder reactions, and theoretical analysis

(2013) Akira Takagi et al.   TETRAHEDRON

A concise synthesis of 3,4-fused spiro[isobenzofuran-3-ones], spiro[furo[3,4- b ]pyridin-5(7 H )-ones], 3-aryl-, and alkylphthalides

(2013) Jeffrey T. Kuethe et al.   TETRAHEDRON

Synthesis of Functionalized Benzo[b]thiophenes by the Intramolecular Copper-Catalyzed Carbomagnesiation of Alkynyl(aryl)thioethers

(2012) Thomas Kunz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and antibacterial evaluation of a novel tricyclic oxaborole-fused fluoroquinolone

(2012) Xianfeng Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Preparations and Reactions of SF5-Substituted Aryl and Heteroaryl Derivatives via Mg and Zn Organometallics

(2012) Annette Frischmuth et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Regioselective Preparation of Heteroaryl-Magnesium Reagents by Using a Br/Mg Exchange

(2012) Christoph Sämann et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Modular Synthesis of Teraryl-Based α-Helix Mimetics, Part 2: Synthesis of 5-Pyridine Boronic Acid Pinacol Ester Building Blocks with Amino Acid Side Chains in 3-Position

(2012) Martin Peters et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of Oxa-B-Ring Analogs of Colchicine through Rh-Catalyzed Intramolecular [5+2] Cycloaddition

(2012) Andreas Ole Termath et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Preparation of amides mediated by isopropylmagnesium chloride under continuous flow conditions

(2012) Juan de M. Muñoz et al.   GREEN CHEMISTRY

Amphiphilic conjugated block copolymers for efficient bulk heterojunction solar cells

(2012) C. Suspène et al.   JOURNAL OF MATERIALS CHEMISTRY

Synthesis of α-Hydroxyacetophenones

(2012) Mark McLaughlin et al.   JOURNAL OF ORGANIC CHEMISTRY

Leaving Group Dependence of the Rates of Halogen–Magnesium Exchange Reactions

(2012) Lei Shi et al.   ORGANIC LETTERS

An Approach to Pin Down the Solid-State Structure of the “Turbo Grignard”

(2012) Florian Blasberg et al.   ORGANOMETALLICS

Synthesis of conjugated diblock copolymers: two mechanistically distinct, sequential living polymerizations using a single catalyst

(2012) Zong-Quan Wu et al.   Polymer Chemistry

Practical one-pot preparation of ketones from aryl and alkyl bromides with aldehydes and DIH via Grignard reagents

(2012) Souya Dohi et al.   TETRAHEDRON

Practical one-pot conversion of aryl bromides and β-bromostyrenes into aromatic nitriles and cinnamonitriles

(2012) Genki Ishii et al.   TETRAHEDRON

Efficient synthesis of substituted quinolines through intramolecular addition of aryl anion to carbonyl carbon

(2012) Yuichi Kobayashi et al.   TETRAHEDRON LETTERS

Efficient synthesis of chlorohydrins using ClCH2MgCl·LiCl

(2012) Rodolfo H.V. Nishimura et al.   TETRAHEDRON LETTERS

Chemoenzymatic synthesis of highly enantiomerically enriched secondary alcohols with a thiazolic core

(2012) Laura Pop et al.   TETRAHEDRON-ASYMMETRY

Transition Metal-Free TEMPO-Catalyzed Oxidative Cross- Coupling of Nitrones with Alkynyl-Grignard Reagents

(2011) Sandip Murarka et al.   ADVANCED SYNTHESIS & CATALYSIS

Highly Diastereoselective Iron-Mediated C(sp2)C(sp3) Cross-Coupling Reactions between Aryl Grignard Reagents and Cyclic Iodohydrine Derivatives

(2011) Andreas K. Steib et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Traceless Solid-Phase Synthesis of Trifluoromethylarenes

(2011) Marion Döbele et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regio- and Chemoselective Metalation of Arenes and Heteroarenes Using Hindered Metal Amide Bases

(2011) Benjamin Haag et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bond Formations between Two Nucleophiles: Transition Metal Catalyzed Oxidative Cross-Coupling Reactions

(2011) Chao Liu et al.   CHEMICAL REVIEWS

Pd- and Ni-Catalyzed Cross-Coupling Reactions of Functionalized Organozinc Reagents with Unsaturated Thioethers

(2011) Laurin Melzig et al.   CHEMISTRY-A EUROPEAN JOURNAL

Total Synthesis of cyclo-Mumbaistatin Analogues through Anionic Homo-Fries Rearrangement

(2011) Stefan Neufeind et al.   CHEMISTRY-A EUROPEAN JOURNAL

Lewis Acid-Promoted Synthesis of Unsymmetrical and Highly Functionalized Carbazoles and Dibenzofurans from Biaryl Triazenes: Application for the Total Synthesis of Clausine C, Clausine R, and Clauraila A

(2011) Weijun Yang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Difunctionalisation of Arenes and Heteroarenes by Directed Metallation and Sulfoxide-Magnesium Exchange

(2011) Laurin Melzig et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Novel and Convenient Synthesis of Benzonitriles: Electrophilic Cyanation of Aryl and Heteroaryl Bromides

(2011) Pazhamalai Anbarasan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis and characterization of all-conjugated copolymers of 3-hexyl-thiophene and EDOT by grignard metathesis polymerization

(2011) Luciano Miozzo et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Cu(I)-Catalyzed, α-Selective, Allylic Alkylation Reactions between Phosphorothioate Esters and Organomagnesium Reagents

(2011) Andrew M. Lauer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rigid P-Chiral Phosphine Ligands with tert-Butylmethylphosphino Groups for Rhodium-Catalyzed Asymmetric Hydrogenation of Functionalized Alkenes

(2011) Tsuneo Imamoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

LiCl-Promoted Chain Growth Kumada Catalyst-Transfer Polycondensation of the “Reversed” Thiophene Monomer

(2011) Shupeng Wu et al.   MACROMOLECULES

Discovery and Process Synthesis of Novel 2,7-Pyrrolo[2,1-f][1,2,4]triazines

(2011) Tho Thieu et al.   ORGANIC LETTERS

Noncryogenic Preparation of Functionalized Arylboronic Esters through a Magnesium−Iodine Exchange with in Situ Quench

(2011) Emilien Demory et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous Preparation of Arylmagnesium Reagents in Flow with Inline IR Monitoring

(2011) Tobias Brodmann et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Totally diastereoselective addition of aryl Grignard reagents to the nitrone-based chiral glycine equivalent MiPNO

(2011) Maryse Thiverny et al.   TETRAHEDRON-ASYMMETRY

Preparation and Regioselective Diels-Alder Reactions of Borylbenzynes: Synthesis of Functionalized Arylboronates

(2010) Takashi Ikawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Convenient Electrophilic Fluorination of Functionalized Aryl and Heteroaryl Magnesium Reagents

(2010) Shigeyuki Yamada et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Dibenzothiophenes and Related Classes of Heterocycles by Using Functionalized Dithiocarbamates

(2010) Marcel Kienle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diisopropylamide and TMP Turbo-Grignard Reagents: A Structural Rationale for their Contrasting Reactivities

(2010) David R. Armstrong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective total synthesis of cytotoxic taiwaniaquinones A and F

(2010) Enrique Alvarez-Manzaneda et al.   CHEMICAL COMMUNICATIONS

A Continuous Flow Process Using a Sequence of Microreactors with In-line IR Analysis for the Preparation of N,N-Diethyl-4-(3-fluorophenylpiperidin-4-ylidenemethyl)benzamide as a Potent and Highly Selective δ-Opioid Receptor Agonist

(2010) Zizheng Qian et al.   CHEMISTRY-A EUROPEAN JOURNAL

Selective Multiple Magnesiations of the Thieno[3,2-b]thiophene Scaffold

(2010) Thomas Kunz et al.   CHEMISTRY-A EUROPEAN JOURNAL

Automated Generation and Reactions of 3-Hydroxymethylindoles in Continuous-Flow Microreactors

(2010) Thomas Tricotet et al.   CHEMISTRY-A EUROPEAN JOURNAL

Transition-Metal-Free Synthesis of Conjugated Polymers from Bis-Grignard Reagents by Using TEMPO as Oxidant

(2010) Modhu Sudan Maji et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Convenient Synthesis of Benzonitriles via Electrophilic Cyanation with N-Cyanobenzimidazole

(2010) Pazhamalai Anbarasan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Efficient and Complementary Methods Offering Access to Synthetically Valuable 1,2-Dibromobenzenes

(2010) Vincent Diemer et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Syntheses of Macrocyclic Bis(bibenzyl) Compounds Derived from Perrottetin E

(2010) Andreas Speicher et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Efficient Synthesis of Deazaguanosine-Derived tRNA Nucleosides PreQ0, PreQ1, and Archaeosine Using the Turbo-Grignard Method

(2010) Tobias Brückl et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Preparation of Functionalized Cyclic Enol Phosphates by Halogen−Magnesium Exchange and Directed Deprotonation Reactions

(2010) Fabian M. Piller et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of 3-Trifluoromethylbenzo[b]furans from Phenols via DirectOrthoFunctionalization by Extended Pummerer Reaction

(2010) Takayuki Kobatake et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition-Metal-Free Sonogashira-Type Coupling ofortho-Substituted Aryl and Alkynyl Grignard Reagents by Using 2,2,6,6-Tetramethylpiperidine-N-oxyl Radical as an Oxidant

(2010) Modhu Sudan Maji et al.   ORGANIC LETTERS

i-PrI Acceleration of Negishi Cross-Coupling Reactions

(2010) Marcel Kienle et al.   ORGANIC LETTERS

Transition-Metal-Free Electrophilic Amination between Aryl Grignard Reagents andN-Chloroamines

(2010) Takuji Hatakeyama et al.   ORGANIC LETTERS

Selection and Development of the Manufacturing Route for EP1Antagonist GSK269984B

(2010) Matthew Whiting et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Scaleable Preparation of Functionalized OrganometallicsviaDirected Ortho Metalation Using Mg- and Zn-Amide Bases

(2010) Stefan H. Wunderlich et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Avant-Garde Metalating Agents: Structural Basis of Alkali-Metal-Mediated Metalation

(2009) Robert E. Mulvey   ACCOUNTS OF CHEMICAL RESEARCH

Manganese-Catalyzed Oxidative Cross-Coupling of Grignard Reagents with Oxygen as an Oxidant

(2009) Gérard Cahiez et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient Synthesis of Aryl Fluorides

(2009) Pazhamalai Anbarasan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

2,3-Functionalization of furans, benzofurans and thiophenes via magnesiation and sulfoxide–magnesium exchange

(2009) Laurin Melzig et al.   CHEMICAL COMMUNICATIONS

Structure Formation Principles and Reactivity of Organolithium Compounds

(2009) Viktoria H. Gessner et al.   CHEMISTRY-A EUROPEAN JOURNAL

Negishi Cross-Couplings Compatible with Unprotected Amide Functions

(2009) Georg Manolikakes et al.   CHEMISTRY-A EUROPEAN JOURNAL

The First Asymmetric Halogen/Metal-Exchange Reaction: Desymmetrization of Alcohols with Enantiotopic Bromoarene Substituents

(2009) Daniel Sälinger et al.   CHEMISTRY-A EUROPEAN JOURNAL

Structure–Reactivity Relationships in Negishi Cross-Coupling Reactions

(2009) Zhi-Bing Dong et al.   CHEMISTRY-A EUROPEAN JOURNAL

Kinetics of Bromine−Magnesium Exchange Reactions in Substituted Bromobenzenes

(2009) Lei Shi et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of α-Amino Amides viaN,O-Acetals Derived from Weinreb Amides

(2009) Sebastian Hirner et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanistic Studies on Ni(dppe)Cl2-Catalyzed Chain-Growth Polymerizations: Evidence for Rate-Determining Reductive Elimination

(2009) Erica L. Lanni et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of (−)-Acutumine

(2009) Fang Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New Synthetic Technologies for the Construction of Heterocycles and Tryptamines

(2009) K. C. Nicolaou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kinetics of Bromine−Magnesium Exchange Reactions in Heteroaryl Bromides

(2009) Lei Shi et al.   ORGANIC LETTERS

Preparation of Polyfunctional Indazoles and Heteroarylazo Compounds Using Highly Functionalized Zinc Reagents

(2009) Benjamin Haag et al.   ORGANIC LETTERS

A straightforward synthesis of 1,3-dichloro-5,8-dihydroisoquinoline by consecutive Stille cross-coupling and metathesis reactions

(2009) Adri van den Hoogenband et al.   TETRAHEDRON LETTERS

Radical Catalysis of Kumada Cross-Coupling Reactions Using Functionalized Grignard Reagents

(2008) Georg Manolikakes et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A General Method formeta andpara Functionalization of Arenes Using TMP2Mg⋅2 LiCl

(2008) Christoph J. Rohbogner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Unmasking Representative Structures of TMP-Active Hauser and Turbo-Hauser Bases

(2008) Pablo García-Álvarez et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mycophenolic acid analogs with a modified metabolic profile

(2008) Liqiang Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Selective Mono- and 1,2-Difunctionalisation of Cyclopentene Derivatives via Mg and Cu Intermediates

(2008) Christina Despotopoulou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Magnesiation of PyridineN-Oxides via Iodine or Bromine−Magnesium Exchange: A Useful Tool for Functionalizing PyridineN-Oxides

(2008) Xin-Fang Duan et al.   JOURNAL OF ORGANIC CHEMISTRY

Grignard Metathesis Chain-Growth Polymerization for Polyfluorenes

(2008) Li Huang et al.   MACROMOLECULES

Grignard Metathesis Method (GRIM): Toward a Universal Method for the Synthesis of Conjugated Polymers

(2008) Mihaela C. Stefan et al.   MACROMOLECULES

Meta- andPara-Difunctionalization of Arenes via a Sulfoxide−Magnesium Exchange Reaction

(2008) Christian B. Rauhut et al.   ORGANIC LETTERS

Oxidative Amination of Cuprated Pyrimidine and Purine Derivatives

(2008) Nadège Boudet et al.   ORGANIC LETTERS

Relative Rates of Bromine–Magnesium Exchange Reactions in Substituted Bromobenzene Derivatives

(2007) Lei Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION