Potential anxiolytic and antidepressant-like effects of luteolin in a chronic constriction injury rat model of neuropathic pain: Role of oxidative stress, neurotrophins, and inflammatory factors

Targeting autophagy and neuroinflammation pathways with plant‐derived natural compounds as potential antidepressant agents

(2022) Tahmineh Mokhtari   PHYTOTHERAPY RESEARCH

Luteolin attenuates Fipronil-induced neurotoxicity through reduction of the ROS-mediated oxidative stress in rat brain mitochondria

(2021) Enayatollah Seydi et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Limonene through Attenuation of Neuroinflammation and Nitrite Level Exerts Antidepressant-Like Effect on Mouse Model of Maternal Separation Stress

(2021) Zahra Lorigooini et al.   BEHAVIOURAL NEUROLOGY

Herbal Medicine for Pain Management: Efficacy and Drug Interactions

(2021) Behdad Jahromi et al.   Pharmaceutics

Therapeutic Potential of Flavonoids in Pain and Inflammation: Mechanisms of Action, Pre-Clinical and Clinical Data, and Pharmaceutical Development

(2020) Camila R. Ferraz et al.   MOLECULES

An Update of Palmitoylethanolamide and Luteolin Effects in Preclinical and Clinical Studies of Neuroinflammatory Events

(2020) Marika Cordaro et al.   Antioxidants

The Role of BDNF on Neural Plasticity in Depression

(2020) Tao Yang et al.   Frontiers in Cellular Neuroscience

Rutin via Increase in the CA3 Diameter of the Hippocampus Exerted Antidepressant-Like Effect in Mouse Model of Maternal Separation Stress: Possible Involvement of NMDA Receptors

(2020) Maryam Anjomshoa et al.   BEHAVIOURAL NEUROLOGY

Neuroprotective effects of hesperidin against methotrexate-induced changes in neurogenesis and oxidative stress in the adult rat

(2020) Jariya Umka Welbat et al.   BIOCHEMICAL PHARMACOLOGY

Emotional and cognitive impairments in the peripheral nerve chronic constriction injury model (CCI) of neuropathic pain: A systematic review

(2020) Diana Fonseca-Rodrigues et al.   BEHAVIOURAL BRAIN RESEARCH

Luteolin shows antidepressant-like effect by inhibiting and downregulating plasma membrane monoamine transporter (PMAT, Slc29a4)

(2019) Shujie Zhu et al.   Journal of Functional Foods

Hippocampal Neurogenesis in Conditions of Chronic Stress Induced by Sciatic Nerve Injury in the Rat

(2019) Evgeniia Egorova et al.   CELLS TISSUES ORGANS

Chronic Pain: Structural and Functional Changes in Brain Structures and Associated Negative Affective States

(2019) Seoyon Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Possible involvement of PI3K/AKT/mTOR signaling pathway in the protective effect of selegiline (deprenyl) against memory impairment following ischemia reperfusion in rat

(2019) Hossein Amini-Khoei et al.   NEUROPEPTIDES

The Role of BDNF in the Neuroimmune Axis Regulation of Mood Disorders

(2019) Yang Jin et al.   Frontiers in Neurology

Prokineticin 2 promotes and sustains neuroinflammation in vincristine treated mice: Focus on pain and emotional like behavior

(2019) Giorgia Moschetti et al.   BRAIN BEHAVIOR AND IMMUNITY

Anxiolytic effects of the flavonoid luteolin in a mouse model of acute colitis

(2019) Vinicius M. Gadotti et al.   Molecular Brain

Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies

(2018) Nur Aziz et al.   JOURNAL OF ETHNOPHARMACOLOGY

The role of hippocampal brain-derived neurotrophic factor in age-related differences in neuropathic pain behavior in rats

(2018) Hiroki Tateiwa et al.   LIFE SCIENCES

Role of the Prefrontal Cortex in Pain Processing

(2018) Wei-Yi Ong et al.   MOLECULAR NEUROBIOLOGY

The Flavone Luteolin Improves Central Nervous System Disorders by Different Mechanisms: A Review

(2018) Zeinab Ashaari et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation

(2018) Bruno Lima Giacobbo et al.   MOLECULAR NEUROBIOLOGY

Neuroprotective Properties of Asiatic Acid against 5-Fluorouracil Chemotherapy in the Hippocampus in an Adult Rat Model

(2018) Jariya Welbat et al.   Nutrients

Luteolin protects against diabetic cardiomyopathy by inhibiting NF-κB-mediated inflammation and activating the Nrf2-mediated antioxidant responses

(2018) Li Li et al.   PHYTOMEDICINE

Anti-inflammatory treatment for major depressive disorder: implications for patients with an elevated immune profile and non-responders to standard antidepressant therapy

(2017) Paula Kopschina Feltes et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The Role of Neural Plasticity in Depression: From Hippocampus to Prefrontal Cortex

(2017) Wei Liu et al.   NEURAL PLASTICITY

Chronic pain and adult hippocampal neurogenesis: translational implications from preclinical studies

(2017) Mariagrazia Grilli   Journal of Pain Research

Natural Flavonoids as Promising Analgesic Candidates: A Systematic Review

(2016) Xiao Xiao et al.   CHEMISTRY & BIODIVERSITY

Nrf2-dependent persistent oxidative stress results in stress-induced vulnerability to depression

(2016) E Bouvier et al.   MOLECULAR PSYCHIATRY

Luteolin as an anti-inflammatory and neuroprotective agent: A brief review

(2015) Seyed Fazel Nabavi et al.   BRAIN RESEARCH BULLETIN

Immune mechanisms linked to depression via oxidative stress and neuroprogression

(2015) Nataliia Bakunina et al.   IMMUNOLOGY

Examining the role of neuroinflammation in major depression

(2015) Melissa Furtado et al.   PSYCHIATRY RESEARCH

Involvement of Nrf2 in Development of Anxiety-Like Behavior by Linking Bcl2 to Oxidative Phosphorylation: Estimation in Rat Hippocampus, Amygdala, and Prefrontal Cortex

(2014) Solmaz Khalifeh et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Allodynia and hyperalgesia in neuropathic pain: clinical manifestations and mechanisms

(2014) Troels S Jensen et al.   LANCET NEUROLOGY

Modulating the delicate glial–neuronal interactions in neuropathic pain: Promises and potential caveats

(2014) Vinod Tiwari et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Effects of intrathecal and intracerebroventricular administration of luteolin in a rat neuropathic pain model

(2014) Koji Hara et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Suicidality in Chronic Pain: Predictors of Suicidal Ideation in Fibromyalgia

(2014) Yolanda Triñanes et al.   Pain Practice

Effects of Palmitoylethanolamide and Luteolin in an Animal Model of Anxiety/Depression

(2013) Rosalia Crupi et al.   CNS & Neurological Disorders-Drug Targets

Psychiatric co-morbidities in patients with chronic peripheral neuropathic pain: A multicentre cohort study

(2013) F. Radat et al.   EUROPEAN JOURNAL OF PAIN

Flavonoids Induce the Synthesis and Secretion of Neurotrophic Factors in Cultured Rat Astrocytes: A Signaling Response Mediated by Estrogen Receptor

(2013) Sherry L. Xu et al.   Evidence-based Complementary and Alternative Medicine

Protective Effect of Luteolin on an Oxidative-Stress Model Induced by Microinjection of Sodium Nitroprusside in Mice

(2013) Qand Agha Nazari et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

NRF2-regulation in brain health and disease: Implication of cerebral inflammation

(2013) Mats Sandberg et al.   NEUROPHARMACOLOGY

Severe Life Stress and Oxidative Stress in the Brain: From Animal Models to Human Pathology

(2012) Stefania Schiavone et al.   ANTIOXIDANTS & REDOX SIGNALING

Luteolin Shows an Antidepressant-Like Effect via Suppressing Endoplasmic Reticulum Stress

(2011) Mitsue Ishisaka et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Visualizing Cell Death in Experimental Focal Cerebral Ischemia: Promises, Problems, and Perspectives

(2011) Marietta Zille et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression

(2011) Brian Leonard et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The Aging Hippocampus

(2011) Kirk I. Erickson et al.   NEUROSCIENTIST

Chronic dizocilpine or apomorphine and development of neuropathy in two animal models II: Effects on brain cytokines and neurotrophins

(2010) Hassen Al-Amin et al.   EXPERIMENTAL NEUROLOGY

Nrf2-ARE stress response mechanism: A control point in oxidative stress-mediated dysfunctions and chronic inflammatory diseases

(2010) Shruti Singh et al.   FREE RADICAL RESEARCH

Neurobiology of depression, fibromyalgia and neuropathic pain

(2010) Vladimir Maletic   Frontiers in Bioscience-Landmark

Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype

(2010) Konstantin Dirscherl et al.   Journal of Neuroinflammation

Neuron–glia crosstalk gets serious: role in pain hypersensitivity

(2008) Ke Ren et al.   Current Opinion in Anesthesiology

Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1

(2008) S. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA