Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis

Value of Information Analysis for Research Decisions—An Introduction: Report 1 of the ISPOR Value of Information Analysis Emerging Good Practices Task Force

(2020) Elisabeth Fenwick et al.   VALUE IN HEALTH

Health economic evaluation of screening and treating children with familial hypercholesterolemia early in life: Many happy returns on investment?

(2020) Zanfina Ademi et al.   ATHEROSCLEROSIS

Why patients with familial hypercholesterolemia are at high cardiovascular risk? Beyond LDL-C levels

(2020) Vanessa Bianconi et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Value of Information Analytical Methods: Report 2 of the ISPOR Value of Information Analysis Emerging Good Practices Task Force

(2020) Claire Rothery et al.   VALUE IN HEALTH

Feasibility and cost of FH cascade screening in Belgium (BEL-CASCADE) including a novel rapid rule-out strategy

(2020) Olivier S. Descamps et al.   ACTA CARDIOLOGICA

Sex differences in cardiovascular morbidity associated with familial hypercholesterolaemia: A retrospective cohort study of the UK Simon Broome register linked to national hospital records

(2020) Barbara Iyen et al.   ATHEROSCLEROSIS

Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials

(2019) Jane Armitage et al.   LANCET

PRELIMINARY RESULTS FROM THE FIRST BELGIAN FAMILIAL HYPERCHOLESTEROLEMIA CASCADE SCREENING (BEL-CASCADE)

(2019) Ernst R. Rietzschel et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Value of Measuring Lipoprotein(a) During Cascade Testing for Familial Hypercholesterolemia

(2019) Katrina L. Ellis et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Establishing a familial hypercholesterolaemia register - The first year

(2019) Myra Tilney   ATHEROSCLEROSIS SUPPLEMENTS

Risk of cardiovascular disease outcomes in primary care subjects with familial hypercholesterolaemia: A cohort study

(2019) Barbara Iyen et al.   ATHEROSCLEROSIS

Sub-optimal cholesterol response to initiation of statins and future risk of cardiovascular disease

(2019) Ralph Kwame Akyea et al.   HEART

Estimating the Marginal Productivity of the English National Health Service From 2003 to 2012

(2019) James Lomas et al.   VALUE IN HEALTH

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk

(2019) François Mach et al.   EUROPEAN HEART JOURNAL

Longitudinal low density lipoprotein cholesterol goal achievement and cardiovascular outcomes among adult patients with familial hypercholesterolemia: The CASCADE FH registry

(2019) P. Barton Duell et al.   ATHEROSCLEROSIS

Current management of children and young people with heterozygous familial hypercholesterolaemia - HEART UK statement of care

(2019) Uma Ramaswami et al.   ATHEROSCLEROSIS

Variants Of Uncertain Significance: Higher Than Average Results In Yorkshire And Humberside For Familial Hypercholesterolaemia

(2019) J. Webster et al.   ATHEROSCLEROSIS SUPPLEMENTS

Results and Lessons of a Pilot Study of Cascade Screening for Familial Hypercholesterolemia in US Primary Care Practices

(2019) Joan Neuner et al.   JOURNAL OF GENERAL INTERNAL MEDICINE

TECH-VER: A Verification Checklist to Reduce Errors in Models and Improve Their Credibility

(2019) Nasuh C. Büyükkaramikli et al.   PHARMACOECONOMICS

New Case Detection by Cascade Testing in Familial Hypercholesterolemia

(2019) Christopher Lee et al.   Circulation-Genomic and Precision Medicine

Reaching detection targets in familial hypercholesterolaemia: Comparison of identification strategies

(2019) David S. Wald et al.   ATHEROSCLEROSIS

Coronary heart disease mortality in treated familial hypercholesterolaemia: Update of the UK Simon Broome FH register

(2018) S.E. Humphries et al.   ATHEROSCLEROSIS

Cost-utility analysis of searching electronic health records and cascade testing to identify and diagnose familial hypercholesterolaemia in England and Wales

(2018) Paul Crosland et al.   ATHEROSCLEROSIS

Universal screening at age 1–2 years as an adjunct to cascade testing for familial hypercholesterolaemia in the UK: A cost-utility analysis

(2018) Ailsa J. McKay et al.   ATHEROSCLEROSIS

Familial Hypercholesterolemia: Cascade Screening in Children and Relatives of the Affected

(2018) Nitika Setia et al.   INDIAN JOURNAL OF PEDIATRICS

Cardiovascular risk in patients with familial hypercholesterolemia using optimal lipid-lowering therapy

(2018) Annette M. Galema-Boers et al.   Journal of Clinical Lipidology

Parent-child genetic testing for familial hypercholesterolaemia in an Australian context

(2018) Jing Pang et al.   JOURNAL OF PAEDIATRICS AND CHILD HEALTH

DETECTION OF FAMILIAL HYPERCHOLESTEROLEMIA IN SOUTH AFRICA VIA CASCADE SCREENING: THE WITS FIND-FH PROGRAM

(2018) Frederick Raal et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Latvian registry of familial hypercholesterolemia: The first report of three-year results

(2018) Gustavs Latkovskis et al.   ATHEROSCLEROSIS

Homozygous familial hypercholesterolaemia in Vietnam: Case series, genetics and cascade testing of families

(2018) Thanh Huong Truong et al.   ATHEROSCLEROSIS

Familial hypercholesterolaemia (fh) genetic testing in the uk

(2018) K. Haralambos et al.   ATHEROSCLEROSIS SUPPLEMENTS

Recall by genotype and cascade screening for familial hypercholesterolemia in a population-based biobank from Estonia

(2018) Maris Alver et al.   GENETICS IN MEDICINE

Clinical Genetic Testing for Familial Hypercholesterolemia

(2018) Amy C. Sturm et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Canadian Cardiovascular Society Position Statement on Familial Hypercholesterolemia: Update 2018

(2018) Liam R. Brunham et al.   CANADIAN JOURNAL OF CARDIOLOGY

2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary

(2018) Scott M. Grundy et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Genetic variations in familial hypercholesterolemia and cascade screening in East Asians

(2018) Melody Lok-Yi Chan et al.   Molecular Genetics & Genomic Medicine

Cost effectiveness of cascade testing for familial hypercholesterolaemia, based on data from familial hypercholesterolaemia services in the UK

(2017) Marion Kerr et al.   EUROPEAN HEART JOURNAL

Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel

(2017) Brian A. Ference et al.   EUROPEAN HEART JOURNAL

Cardiovascular Disease Risk And Risk Factors Associated With Familial Hypercholesterolemia: A Systematic Review

(2017) G Kruse et al.   VALUE IN HEALTH

Retrospective examination of lipid-lowering treatment patterns in a real-world high-risk cohort in the UK in 2014: comparison with the National Institute for Health and Care Excellence (NICE) 2014 lipid modification guidelines

(2017) Dylan L Steen et al.   BMJ Open

Estimating the prevalence of heterozygous familial hypercholesterolaemia: a systematic review and meta-analysis

(2017) Leo E Akioyamen et al.   BMJ Open

AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both

(2017) Beverley J Shea et al.   BMJ-British Medical Journal

AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both

(2017) Beverley J Shea et al.   BMJ-British Medical Journal

Long-Term Risk of Atherosclerotic Cardiovascular Disease in US Adults With the Familial Hypercholesterolemia PhenotypeClinical Perspective

(2016) Amanda M. Perak et al.   CIRCULATION

Cardiovascular Disease Risk Associated With Familial Hypercholesterolemia: A Systematic Review of the Literature

(2016) Bruce Wong et al.   CLINICAL THERAPEUTICS

Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217

(2016) Marianne Benn et al.   EUROPEAN HEART JOURNAL

Percent reduction in LDL cholesterol following high-intensity statin therapy: potential implications for guidelines and for the prescription of emerging lipid-lowering agents

(2016) Paul M Ridker et al.   EUROPEAN HEART JOURNAL

Therapeutic efficacy of PCSK9 monoclonal antibodies in statin-nonresponsive patients with hypercholesterolemia and dyslipidemia: A systematic review and meta-analysis

(2016) Wan Peng et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Data Resource Profile: The Scottish National Prescribing Information System (PIS)

(2016) Samantha Alvarez-Madrazo et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Cost-effectiveness of PCSK9 Inhibitor Therapy in Patients With Heterozygous Familial Hypercholesterolemia or Atherosclerotic Cardiovascular Disease

(2016) Dhruv S. Kazi et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Lipid Screening in Childhood and Adolescence for Detection of Familial Hypercholesterolemia

(2016) Paula Lozano et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Combined Cascade Screening And Patient Education For Familial Hypercholesterolemia: Genetic Results From A Family Shared Medical Appointment Pilot Study

(2016) Tina Davis et al.   Journal of Clinical Lipidology

flexsurv: A Platform for Parametric Survival Modeling inR

(2016) Christopher Jackson   Journal of Statistical Software

Extrapolation of Survival Curves from Cancer Trials Using External Information

(2016) Patricia Guyot et al.   MEDICAL DECISION MAKING

Child–Parent Familial Hypercholesterolemia Screening in Primary Care

(2016) David S. Wald et al.   NEW ENGLAND JOURNAL OF MEDICINE

Familial hypercholesterolemia in Brazil: Cascade screening program, clinical and genetic aspects

(2015) Cinthia E. Jannes et al.   ATHEROSCLEROSIS

Improving identification of familial hypercholesterolaemia in primary care: Derivation and validation of the familial hypercholesterolaemia case ascertainment tool (FAMCAT)

(2015) Stephen F. Weng et al.   ATHEROSCLEROSIS

Effectiveness of genetic cascade screening for familial hypercholesterolaemia using a centrally co-ordinated clinical service: An Australian experience

(2015) Damon A. Bell et al.   ATHEROSCLEROSIS

Clinical experience of scoring criteria for Familial Hypercholesterolaemia (FH) genetic testing in Wales

(2015) K. Haralambos et al.   ATHEROSCLEROSIS

Safety and efficacy of anti-PCSK9 antibodies: a meta-analysis of 25 randomized, controlled trials

(2015) Xin-Lin Zhang et al.   BMC Medicine

Improving the cost-effectiveness equation of cascade testing for familial hypercholesterolaemia

(2015) Robert Pears et al.   CURRENT OPINION IN LIPIDOLOGY

Methods for the estimation of the National Institute for Health and Care Excellence cost-effectiveness threshold

(2015) Karl Claxton et al.   HEALTH TECHNOLOGY ASSESSMENT

Data Resource Profile: Clinical Practice Research Datalink (CPRD)

(2015) Emily Herrett et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Effect of Naturally Random Allocation to Lower Low-Density Lipoprotein Cholesterol on the Risk of Coronary Heart Disease Mediated by Polymorphisms in NPC1L1, HMGCR, or Both

(2015) Brian A. Ference et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation

(2015) L. Shamseer et al.   BMJ-British Medical Journal

Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation

(2015) L. Shamseer et al.   BMJ-British Medical Journal

Effectiveness of Combination Therapy With Statin and Another Lipid-Modifying Agent Compared With Intensified Statin Monotherapy

(2014) Kimberly A. Gudzune et al.   ANNALS OF INTERNAL MEDICINE

Mendelian randomization of blood lipids for coronary heart disease

(2014) Michael V. Holmes et al.   EUROPEAN HEART JOURNAL

Ezetimibe for the treatment of hypercholesterolaemia: a systematic review and economic evaluation

(2014) R Ara et al.   HEALTH TECHNOLOGY ASSESSMENT

A cardiovascular disease policy model that predicts life expectancy taking into account socioeconomic deprivation

(2014) J D Lewsey et al.   HEART

Cascade screening based on genetic testing is cost-effective: Evidence for the implementation of models of care for familial hypercholesterolemia

(2014) Zanfina Ademi et al.   Journal of Clinical Lipidology

QUADAS-2: A Revised Tool for the Quality Assessment of Diagnostic Accuracy Studies

(2013) Penny F. Whiting   ANNALS OF INTERNAL MEDICINE

Analysis of the frequency and spectrum of mutations recognised to cause familial hypercholesterolaemia in routine clinical practice in a UK specialist hospital lipid clinic

(2013) Marta Futema et al.   ATHEROSCLEROSIS

Implementation of a multidisciplinary approach to diagnosis and management of familial hypercholesterolaemia (FH) in Wales: The role of the FH specialist nurse

(2013) R. Edwards et al.   ATHEROSCLEROSIS

Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: Consensus Statement of the European Atherosclerosis Society

(2013) B. G. Nordestgaard et al.   EUROPEAN HEART JOURNAL

A systematic review of economic evaluations of the detection and treatment of familial hypercholesterolemia

(2013) Zanfina Ademi et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Is a Cutoff of 10% Appropriate for the Change-in-Estimate Criterion of Confounder Identification?

(2013) Paul H. Lee   JOURNAL OF EPIDEMIOLOGY

Survival Analysis for Economic Evaluations Alongside Clinical Trials—Extrapolation with Patient-Level Data

(2013) Nicholas R. Latimer   MEDICAL DECISION MAKING

Statin treatment of children with familial hypercholesterolemia – Trying to balance incomplete evidence of long-term safety and clinical accountability: Are we approaching a consensus?

(2012) Alpo Vuorio et al.   ATHEROSCLEROSIS

Discriminative Ability of LDL-Cholesterol to Identify Patients With Familial Hypercholesterolemia

(2012) Roeland Huijgen et al.   Circulation-Cardiovascular Genetics

European Guidelines on cardiovascular disease prevention in clinical practice (version 2012): The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts) * Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR)

(2012) et al.   EUROPEAN HEART JOURNAL

Effect of Long-Term Exposure to Lower Low-Density Lipoprotein Cholesterol Beginning Early in Life on the Risk of Coronary Heart Disease

(2012) Brian A. Ference et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Current State of Niacin in Cardiovascular Disease Prevention

(2012) Paul M. Lavigne et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Paediatric screening for hypercholesterolaemia in Europe: Table 1

(2011) D M Kusters et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Genetic screening for familial hypercholesterolaemia in a cardiothoracic tertiary referral centre

(2011) J. Breen et al.   ATHEROSCLEROSIS

Pitavastatin Calcium: Clinical Review of a New Antihyperlipidemic Medication

(2011) Laurie L. Yee et al.   CLINICAL THERAPEUTICS

Probabilistic cost-effectiveness analysis of cascade screening for familial hypercholesterolaemia using alternative diagnostic and identification strategies

(2011) L. Nherera et al.   HEART

Treatment of adults with Familial Hypercholesterolemia and evidence for treatment: Recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia

(2011) Jennifer G. Robinson et al.   Journal of Clinical Lipidology

Familial Hypercholesterolemias: Prevalence, genetics, diagnosis and screening recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia

(2011) Paul N. Hopkins et al.   Journal of Clinical Lipidology

Familial Hypercholesterolemia: Screening, diagnosis and management of pediatric and adult patients

(2011) Anne C. Goldberg et al.   Journal of Clinical Lipidology

Meta-analysis of the comparative efficacy and safety of pitavastatin and atorvastatin in patients with dyslipidaemia

(2011) N. Poolsup et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Análisis coste-efectividad de un programa de cribado genético en familiares directos de pacientes con hipercolesterolemia familiar en España

(2011) Juan Oliva et al.   REVISTA ESPANOLA DE CARDIOLOGIA

Populating an Economic Model with Health State Utility Values: Moving toward Better Practice

(2010) Roberta Ara et al.   VALUE IN HEALTH

Comparison of sequential rosuvastatin doses in hypercholesterolaemia: a meta-analysis of randomised controlled trials

(2009) Joe Gray et al.   CURRENT MEDICAL RESEARCH AND OPINION

Cost-effectiveness analysis of the use of a high-intensity statin compared to a low-intensity statin in the management of patients with familial hypercholesterolaemia

(2009) L. Nherera et al.   CURRENT MEDICAL RESEARCH AND OPINION

Controversies in familial hypercholesterolaemia: recommendations of the NICE Guideline Development Group for the identification and management of familial hypercholesterolaemia

(2009) R Minhas et al.   HEART

A systematic review and meta-analysis on the therapeutic equivalence of statins

(2009) T.-C. Weng et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Lipid management in the prevention of stroke: review and updated meta-analysis of statins for stroke prevention

(2009) Pierre Amarenco et al.   LANCET NEUROLOGY

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE

Comparison of Genetic Versus Clinical Diagnosis in Familial Hypercholesterolemia

(2008) Fernando Civeira et al.   AMERICAN JOURNAL OF CARDIOLOGY

Development of sensitive and specific age- and gender-specific low-density lipoprotein cholesterol cutoffs for diagnosis of first-degree relatives with familial hypercholesterolaemia in cascade testing

(2008) Brian Starr et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study

(2008) Patrick Linsel-Nitschke et al.   PLoS One

Optimal Cost-Effectiveness Decisions: The Role of the Cost-Effectiveness Acceptability Curve (CEAC), the Cost-Effectiveness Acceptability Frontier (CEAF), and the Expected Value of Perfection Information (EVPI)

(2008) Garry R. Barton et al.   VALUE IN HEALTH

Family tracing to identify patients with Familial Hypercholesterolaemia: the second Audit of the Department of Health Familial Hypercholesterolaemia Cascade Testing Project

(2008) S G Hadfield et al.   ANNALS OF CLINICAL BIOCHEMISTRY