Veliparib (ABT-888), a PARP inhibitor potentiates the cytotoxic activity of 5-fluorouracil by inhibiting MMR pathway through deregulation of MSH6 in colorectal cancer stem cells

Synthesis of Veliparib Prodrugs and Determination of Drug-Release-Dependent PARP-1 Inhibition

(2023) Matteo Borgini et al.   ACS Medicinal Chemistry Letters

Quinacrine inhibits cMET-mediated metastasis and angiogenesis in breast cancer stem cells

(2023) Biswajit Das et al.   Journal of Cell Communication and Signaling

Quinacrine inhibits HIF-1α/VEGF-A mediated angiogenesis by disrupting the interaction between cMET and ABCG2 in patient-derived breast cancer stem cells

(2023) Biswajit Das et al.   PHYTOMEDICINE

Combination of talazoparib and olaparib enhanced the curcumin-mediated apoptosis in oral cancer cells by PARP-1 trapping

(2022) Subhajit Chatterjee et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Microsatellite instability testing in colorectal patients with Lynch syndrome: lessons learned from a case report and how to avoid such pitfalls

(2022) Sola Adeleke et al.   Personalized Medicine

Olaparib enhances the Resveratrol-mediated apoptosis in breast cancer cells by inhibiting the homologous recombination repair pathway

(2022) Saptarshi Sinha et al.   EXPERIMENTAL CELL RESEARCH

Targeting cancer stem cells in the tumor microenvironment: An emerging role of PARP inhibitors

(2022) Subarno Paul et al.   PHARMACOLOGICAL RESEARCH

Quinacrine and Curcumin in combination decreased the breast cancer angiogenesis by modulating ABCG2 via VEGF A

(2022) Deepika Nayak et al.   Journal of Cell Communication and Signaling

Surgery for T4 Colorectal Cancer in Older Patients: Determinants of Outcomes

(2022) Michael Osseis et al.   Journal of Personalized Medicine

Resveratrol nanoparticle attenuates metastasis and angiogenesis by deregulating inflammatory cytokines through inhibition of CAFs in oral cancer by CXCL-12/IL-6-dependent pathway

(2022) Rajalaxmi Pradhan et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

5-Fluorouracil (5-FU) resistance and the new strategy to enhance the sensitivity against cancer: Implication of DNA repair inhibition

(2021) Chinmayee Sethy et al.   BIOMEDICINE & PHARMACOTHERAPY

Olaparib enhances curcumin-mediated apoptosis in oral cancer cells by inducing PARP trapping through modulation of BER and chromatin assembly

(2021) Sefinew Molla et al.   DNA REPAIR

PARP1-modulated chromatin remodeling is a new target for cancer treatment

(2021) Saptarshi Sinha et al.   MEDICAL ONCOLOGY

Exploration of Benzo[b]carbazole-6,11-diones as anticancer agents: Synthesis and studies of hTopoIIα inhibition and apoptotic effects

(2021) Shailendra Sisodiya et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

NIR irradiation enhances the apoptotic potentiality of quinacrine-gold hybrid nanoparticles by modulation of HSP-70 in oral cancer stem cells

(2021) Somya Ranjan Dash et al.   Nanomedicine-Nanotechnology Biology and Medicine

Tumor Microenvironment

(2020) Borros Arneth   Medicina-Lithuania

5‐Fluorouracil resistance mechanisms in colorectal cancer: From classical pathways to promising processes

(2020) Sabrina Blondy et al.   CANCER SCIENCE

Clinical significance of a pvrl 4 encoded gene Nectin-4 in metastasis and angiogenesis for tumor relapse

(2019) Chinmayee Sethy et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Quinacrine and curcumin synergistically increased the breast cancer stem cells death by inhibiting ABCG2 and modulating DNA damage repair pathway

(2019) Deepika Nayak et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment

(2018) Lan Thi Hanh Phi et al.   Stem Cells International

ABT-888 and quinacrine induced apoptosis in metastatic breast cancer stem cells by inhibiting base excision repair via adenomatous polyposis coli

(2016) Sumit Siddharth et al.   DNA REPAIR

Pharmacologic resistance in colorectal cancer: a review

(2015) William A. Hammond et al.   Therapeutic Advances in Medical Oncology

5-Fluorouracil mediated anti-cancer activity in colon cancer cells is through the induction of Adenomatous Polyposis Coli: Implication of the long-patch base excision repair pathway

(2014) Dipon Das et al.   DNA REPAIR

Targeting DNA repair pathways for cancer treatment: what’s new?

(2014) Mark R Kelley et al.   Future Oncology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

PARP-1 enhances the mismatch-dependence of 5′-directed excision in human mismatch repair in vitro

(2011) Yiyong Liu et al.   DNA REPAIR

DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets

(2009) Long Shan Li et al.   BRITISH JOURNAL OF PHARMACOLOGY

Participation of DNA repair in the response to 5-fluorouracil

(2008) M. D. Wyatt et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine

(2008) Angen Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY