Unbiased whole genome detection of ultrarare off‐target mutations in genome‐edited cell populations by HiFi sequencing

Chemical and Biological Approaches to Interrogate off-Target Effects of Genome Editing Tools

(2023) Zhixin Lei et al.   ACS Chemical Biology

CRISPR technology: A decade of genome editing is only the beginning

(2023) Joy Y. Wang et al.   SCIENCE

Genome‐wide detection of ultralow‐frequency substitution mutations in cultures of mouse lymphoma L5178Y cells and Caenorhabditis elegans worms by PacBio sequencing

(2022) Jaime A. Miranda et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

DNA base editing in nuclear and organellar genomes

(2022) Junjie Tan et al.   TRENDS IN GENETICS

Evaluation of the mutagenic effects of Molnupiravir and N4 ‐hydroxycytidine in bacterial and mammalian cells by HiFi sequencing

(2022) Jaime A. Miranda et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

PacBio sequencing detects genome‐wide ultra‐low‐frequency substitution mutations resulting from exposure to chemical mutagens

(2021) Javier R. Revollo et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Detect-seq reveals out-of-protospacer editing and target-strand editing by cytosine base editors

(2021) Zhixin Lei et al.   NATURE METHODS

Current Status and Challenges of DNA Base Editing Tools

(2020) You Kyeong Jeong et al.   MOLECULAR THERAPY

Latest Developed Strategies to Minimize the Off-Target Effects in CRISPR-Cas-Mediated Genome Editing

(2020) Muhammad Naeem et al.   Cells

GOTI, a method to identify genome-wide off-target effects of genome editing in mouse embryos

(2020) Erwei Zuo et al.   Nature Protocols

Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos

(2019) Erwei Zuo et al.   SCIENCE

Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice

(2019) Shuai Jin et al.   SCIENCE

Next‐Generation Genotoxicology: Using Modern Sequencing Technologies to Assess Somatic Mutagenesis and Cancer Risk

(2019) Jesse J. Salk et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Targeting specificity of APOBEC-based cytosine base editor in human iPSCs determined by whole genome sequencing

(2019) Erica McGrath et al.   Nature Communications

Genome-wide mutation detection by interclonal genetic variation

(2018) Javier R. Revollo et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Enhancing the accuracy of next-generation sequencing for detecting rare and subclonal mutations

(2018) Jesse J. Salk et al.   NATURE REVIEWS GENETICS

Deaminase-mediated multiplex genome editing in Escherichia coli

(2018) Satomi Banno et al.   Nature Microbiology