Live cell transcription-coupled nucleotide excision repair dynamics revisited

CRISPR/Cas9-mediated genome editing assists protein dynamics studies in live cells

(2022) Carlos Carrasco-Padilla et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

DNA damage-induced transcription stress triggers the genome-wide degradation of promoter-bound Pol II

(2022) Barbara Steurer et al.   Nature Communications

Filamentous nuclear actin regulation of PML NBs during the DNA damage response is deregulated by prelamin A

(2022) Andrew M. Cobb et al.   Cell Death & Disease

Tissue-Specific DNA Repair Activity of ERCC-1/XPF-1

(2021) Mariangela Sabatella et al.   Cell Reports

Current and emerging roles of Cockayne syndrome group B (CSB) protein

(2021) Vinod Tiwari et al.   NUCLEIC ACIDS RESEARCH

A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair

(2021) Diana van den Heuvel et al.   Nature Communications

Structural basis of human transcription–DNA repair coupling

(2021) Goran Kokic et al.   NATURE

Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability

(2021) Marit E. Geijer et al.   NATURE CELL BIOLOGY

Role of BRCA2 DNA-binding and C-terminal domain in its mobility and conformation in DNA repair

(2021) Maarten W Paul et al.   eLife

C. elegans TFIIH subunit GTF-2H5/TTDA is a non-essential transcription factor indispensable for DNA repair

(2021) Karen L. Thijssen et al.   Communications Biology

Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair

(2020) Yuka Nakazawa et al.   CELL

Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

(2020) Ana Tufegdžić Vidaković et al.   CELL

The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II

(2020) Yana van der Weegen et al.   Nature Communications

A Genetic Map of the Response to DNA Damage in Human Cells

(2020) Michele Olivieri et al.   CELL

Ubiquitin and TFIIH-stimulated DDB2 dissociation drives DNA damage handover in nucleotide excision repair

(2020) Cristina Ribeiro-Silva et al.   Nature Communications

Spironolactone-induced XPB degradation requires TFIIH integrity and ubiquitin-selective segregase VCP/p97

(2020) Anil K. Chauhan et al.   CELL CYCLE

FACT subunit Spt16 controls UVSSA recruitment to lesion-stalled RNA Pol II and stimulates TC-NER

(2019) Franziska Wienholz et al.   NUCLEIC ACIDS RESEARCH

Cell-type specific concentration regulation of the basal transcription factor TFIIH in XPBy/y mice model

(2019) Lise-Marie Donnio et al.   Cancer Cell International

Endogenous Fluorescence Tagging by CRISPR

(2019) Hassan Bukhari et al.   TRENDS IN CELL BIOLOGY

Generation and validation of homozygous fluorescent knock-in cells using CRISPR–Cas9 genome editing

(2018) Birgit Koch et al.   Nature Protocols

Live-cell analysis of endogenous GFP-RPB1 uncovers rapid turnover of initiating and promoter-paused RNA Polymerase II

(2018) Barbara Steurer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ZNF185 is a p53 target gene following DNA damage

(2018) Artem Smirnov et al.   Aging-US

Structural basis for the initiation of eukaryotic transcription-coupled DNA repair

(2017) Jun Xu et al.   NATURE

Common TFIIH recruitment mechanism in global genome and transcription-coupled repair subpathways

(2017) Masahiko Okuda et al.   NUCLEIC ACIDS RESEARCH

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Chromosome territory relocation during DNA repair requires nuclear myosin 1 recruitment to chromatin mediated by ϒ-H2AX signaling

(2016) Mugdha Kulashreshtha et al.   NUCLEIC ACIDS RESEARCH

Characterizing Protein–Protein Interactions Using Mass Spectrometry: Challenges and Opportunities

(2016) Arne H. Smits et al.   TRENDS IN BIOTECHNOLOGY

Multiomic Analysis of the UV-Induced DNA Damage Response

(2016) Stefan Boeing et al.   Cell Reports

Improving brightness and photostability of green and red fluorescent proteins for live cell imaging and FRET reporting

(2016) Bryce T. Bajar et al.   Scientific Reports

The loss of ATP2C1 impairs the DNA damage response and induces altered skin homeostasis: Consequences for epidermal biology in Hailey-Hailey disease

(2016) Samantha Cialfi et al.   Scientific Reports

MCM9 Is Required for Mammalian DNA Mismatch Repair

(2015) Sabine Traver et al.   MOLECULAR CELL

Tripartite DNA Lesion Recognition and Verification by XPC, TFIIH, and XPA in Nucleotide Excision Repair

(2015) Chia-Lung Li et al.   MOLECULAR CELL

Expanding the Biologist’s Toolkit with CRISPR-Cas9

(2015) Samuel H. Sternberg et al.   MOLECULAR CELL

SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair

(2015) Loes van Cuijk et al.   Nature Communications

A Small Molecule Screen Identifies an Inhibitor of DNA Repair Inducing the Degradation of TFIIH and the Chemosensitization of Tumor Cells to Platinum

(2014) Sergey Alekseev et al.   CHEMISTRY & BIOLOGY

BRCA2 diffuses as oligomeric clusters with RAD51 and changes mobility after DNA damage in live cells

(2014) Marcel Reuter et al.   JOURNAL OF CELL BIOLOGY

A robust pipeline for rapid production of versatile nanobody repertoires

(2014) Peter C Fridy et al.   NATURE METHODS

Understanding nucleotide excision repair and its roles in cancer and ageing

(2014) Jurgen A. Marteijn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CSB interacts with SNM1A and promotes DNA interstrand crosslink processing

(2014) Teruaki Iyama et al.   NUCLEIC ACIDS RESEARCH

Mcm8 and Mcm9 Form a Complex that Functions in Homologous Recombination Repair Induced by DNA Interstrand Crosslinks

(2012) Kohei Nishimura et al.   MOLECULAR CELL

Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass

(2012) Lou K. Povlsen et al.   NATURE CELL BIOLOGY

Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair

(2012) Yuka Nakazawa et al.   NATURE GENETICS

Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair

(2012) Xue Zhang et al.   NATURE GENETICS

UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair

(2012) Petra Schwertman et al.   NATURE GENETICS

The Molecular Basis of CRL4DDB2/CSA Ubiquitin Ligase Architecture, Targeting, and Activation

(2011) Eric S. Fischer et al.   CELL

Dynamics of mammalian NER proteins

(2011) Wim Vermeulen   DNA REPAIR

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

UV-Induced Association of the CSB Remodeling Protein with Chromatin Requires ATP-Dependent Relief of N-Terminal Autorepression

(2010) Robert J. Lake et al.   MOLECULAR CELL

ATF3 and p15PAF are novel gatekeepers of genomic integrity upon UV stress

(2009) L Turchi et al.   CELL DEATH AND DIFFERENTIATION

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

(2009) Teresa A. Soucy et al.   NATURE

DNA Damage, Aging, and Cancer

(2009) Jan H.J. Hoeijmakers   NEW ENGLAND JOURNAL OF MEDICINE

Differentiation Driven Changes in the Dynamic Organization of Basal Transcription Initiation

(2009) Giuseppina Giglia-Mari et al.   PLOS BIOLOGY

Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation

(2008) David M. Duda et al.   CELL