BRCA2 diffuses as oligomeric clusters with RAD51 and changes mobility after DNA damage in live cells

Taking it one step at a time in homologous recombination repair

(2014) Humberto Sanchez et al.   DNA REPAIR

Androgen receptor complexes probe DNA for recognition sequences by short random interactions

(2014) M. E. Van Royen et al.   JOURNAL OF CELL SCIENCE

Objective comparison of particle tracking methods

(2014) Nicolas Chenouard et al.   NATURE METHODS

Structure and mechanism of action of the BRCA2 breast cancer tumor suppressor

(2014) Taha Shahid et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Endogenous levels of Rad51 and Brca2 are required for homologous recombination and regulated by homeostatic re-balancing

(2013) Alissa C. Magwood et al.   DNA REPAIR

A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization

(2013) Anand D Jeyasekharan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A benchmark for chromatin binding measurements in live cells

(2012) Davide Mazza et al.   NUCLEIC ACIDS RESEARCH

Closed-form density-based framework for automatic detection of cellular morphology changes

(2012) T. Duong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How to quantify protein diffusion in the bacterial membrane

(2011) Siet M. J. L. van den Wildenberg et al.   BIOPOLYMERS

Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11

(2011) Katharina Schlacher et al.   CELL

γH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization

(2011) Markus Löbrich et al.   CELL CYCLE

ATP-dependent and independent functions of Rad54 in genome maintenance

(2011) Sheba Agarwal et al.   JOURNAL OF CELL BIOLOGY

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Two classes of BRC repeats in BRCA2 promote RAD51 nucleoprotein filament function by distinct mechanisms

(2011) A. Carreira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition

(2011) P. M. Krawczyk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasticity of BRCA2 Function in Homologous Recombination: Genetic Interactions of the PALB2 and DNA Binding Domains

(2011) Nicolas Siaud et al.   PLoS Genetics

Regulation of Homologous Recombination in Eukaryotes

(2010) Wolf-Dietrich Heyer et al.   Annual Review of Genetics

Dissecting chromatin interactions in living cells from protein mobility maps

(2010) Fabian Erdel et al.   CHROMOSOME RESEARCH

In Vitro Reconstitution of the Functional Interplay between MCAK and EB3 at Microtubule Plus Ends

(2010) Susana Montenegro Gouveia et al.   CURRENT BIOLOGY

Purified human BRCA2 stimulates RAD51-mediated recombination

(2010) Ryan B. Jensen et al.   NATURE

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA

(2010) Jie Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA

(2010) Tina Thorslund et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA damage regulates the mobility of Brca2 within the nucleoplasm of living cells

(2010) A. D. Jeyasekharan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single ovalbumin molecules exploring nucleoplasm and nucleoli of living cell nuclei

(2009) Jasmin Speil et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice

(2009) K. Anastassiadis et al.   Disease Models & Mechanisms

NBS1 cooperates with homologous recombination to counteract chromosome breakage during replication

(2009) Linda Brugmans et al.   DNA REPAIR

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

(2009) Dirk Hockemeyer et al.   NATURE BIOTECHNOLOGY

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase

(2009) Eeson Rajendra et al.   NUCLEIC ACIDS RESEARCH

Single-Molecule Approach to Molecular Biology in Living Bacterial Cells

(2008) X. Sunney Xie et al.   Annual Review of Biophysics

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Highly inclined thin illumination enables clear single-molecule imaging in cells

(2008) Makio Tokunaga et al.   NATURE METHODS

Robust single-particle tracking in live-cell time-lapse sequences

(2008) Khuloud Jaqaman et al.   NATURE METHODS

Random Time-Scale Invariant Diffusion and Transport Coefficients

(2008) Y. He et al.   PHYSICAL REVIEW LETTERS

Probing Intranuclear Environments at the Single-Molecule Level

(2007) David Grünwald et al.   BIOPHYSICAL JOURNAL