Multi-omic prediction of incident type 2 diabetes

A proteo-transcriptomic map of non-alcoholic fatty liver disease signatures

(2023) Olivier Govaere et al.   Nature Metabolism

Proteomic signatures for identification of impaired glucose tolerance

(2022) Julia Carrasco-Zanini et al.   NATURE MEDICINE

A cross-platform approach identifies genetic regulators of human metabolism and health

(2021) Luca A. Lotta et al.   NATURE GENETICS

Plasma metabolites to profile pathways in noncommunicable disease multimorbidity

(2021) Maik Pietzner et al.   NATURE MEDICINE

Proteomic profiling reveals biomarkers and pathways in type 2 diabetes risk

(2021) Debby Ngo et al.   JCI Insight

Performance of Risk Assessment Models for Prevalent or Undiagnosed Type 2 Diabetes Mellitus in a Multi-Ethnic Population—The Helius Study

(2021) Morgan O. Obura et al.   Global Heart

Efficacy of lifestyle intervention in adults with impaired glucose tolerance with and without impaired fasting plasma glucose: A post hoc analysis of Da Qing Diabetes Prevention Outcome Study

(2021) Qiuhong Gong et al.   DIABETES OBESITY & METABOLISM

Circulating Protein Signatures and Causal Candidates for Type 2 Diabetes

(2020) Valborg Gudmundsdottir et al.   DIABETES

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

(2020) Marijana Vujkovic et al.   NATURE GENETICS

Integrating Genetics and the Plasma Proteome to Predict the Risk of Type 2 Diabetes

(2020) Julia Carrasco Zanini et al.   Current Diabetes Reports

LDpred2: better, faster, stronger

(2020) Florian Privé et al.   BIOINFORMATICS

Plasma Vitamin C and Type 2 Diabetes: Genome-Wide Association Study and Mendelian Randomization Analysis in European Populations

(2020) Ju-Sheng Zheng et al.   DIABETES CARE

Genetic Risk Scores for Diabetes Diagnosis and Precision Medicine

(2019) Miriam S Udler et al.   ENDOCRINE REVIEWS

Plasma protein patterns as comprehensive indicators of health

(2019) Stephen A. Williams et al.   NATURE MEDICINE

Efficient analysis of large-scale genome-wide data with two R packages: bigstatsr and bigsnpr

(2018) Florian Privé et al.   BIOINFORMATICS

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

(2018) Anubha Mahajan et al.   NATURE GENETICS

Metabolomics based markers predict type 2 diabetes in a 14-year follow-up study

(2017) Jun Liu et al.   Metabolomics

Early Detection and Treatment of Type 2 Diabetes Reduce Cardiovascular Morbidity and Mortality: A Simulation of the Results of the Anglo-Danish-Dutch Study of Intensive Treatment in People With Screen-Detected Diabetes in Primary Care (ADDITION-Europe)

(2015) William H. Herman et al.   DIABETES CARE

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Building Predictive Models inRUsing thecaretPackage

(2015) Max Kuhn   Journal of Statistical Software

Regularization Paths for Generalized Linear Models via Coordinate Descent

(2015) Jerome Friedman et al.   Journal of Statistical Software

Sixty-Five Common Genetic Variants and Prediction of Type 2 Diabetes

(2014) Philippa J. Talmud et al.   DIABETES

Gene-Lifestyle Interaction and Type 2 Diabetes: The EPIC InterAct Case-Cohort Study

(2014) Claudia Langenberg et al.   PLOS MEDICINE

Non-invasive risk scores for prediction of type 2 diabetes (EPIC-InterAct): a validation of existing models

(2013) Andre Pascal Kengne et al.   Lancet Diabetes & Endocrinology

Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach

(2012) A. Floegel et al.   DIABETES

How much does screening bring forward the diagnosis of type 2 diabetes and reduce complications? Twelve year follow-up of the Ely cohort

(2012) M. Rahman et al.   DIABETOLOGIA

Prediction models for risk of developing type 2 diabetes: systematic literature search and independent external validation study

(2012) A. Abbasi et al.   BMJ-British Medical Journal

MissForest--non-parametric missing value imputation for mixed-type data

(2011) D. J. Stekhoven et al.   BIOINFORMATICS

Updated Genetic Score Based on 34 Confirmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program

(2011) M.-F. Hivert et al.   DIABETES

Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study

(2011)   DIABETOLOGIA

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

A systematic expression analysis implicates Plexin-B2 and its ligand Sema4C in the regulation of the vascular and endocrine system

(2010) Matthias Zielonka et al.   EXPERIMENTAL CELL RESEARCH

Low levels of insulin-like growth-factor-binding protein-1 (IGFBP-1) are prospectively associated with the incidence of type 2 diabetes and impaired glucose tolerance (IGT): The Söderåkra Cardiovascular Risk Factor Study

(2009) U. Petersson et al.   DIABETES & METABOLISM

A simple risk score identifies individuals at high risk of developing Type 2 diabetes: a prospective cohort study

(2008) M. Rahman et al.   FAMILY PRACTICE

Genotype Score in Addition to Common Risk Factors for Prediction of Type 2 Diabetes

(2008) James B. Meigs et al.   NEW ENGLAND JOURNAL OF MEDICINE