Proteomic profiling reveals biomarkers and pathways in type 2 diabetes risk

Circulating Protein Signatures and Causal Candidates for Type 2 Diabetes

(2020) Valborg Gudmundsdottir et al.   DIABETES

PhenoScanner V2: an expanded tool for searching human genotype–phenotype associations

(2019) Mihir A Kamat et al.   BIOINFORMATICS

Exome sequencing of Finnish isolates enhances rare-variant association power

(2019) Adam E. Locke et al.   NATURE

WITHDRAWN:IDF Diabetes Atlas: Projections of the prevalence of hyperglycaemia in pregnancy in 2019 and beyond: results from the International Diabetes Federation Diabetes Atlas, 9th edition

(2019) Lili Yuen et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Identification of the Secreted Proteins Originated from Primary Human Hepatocytes and HepG2 Cells

(2019) Andras Franko et al.   Nutrients

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

(2018) Anubha Mahajan et al.   NATURE GENETICS

Ablation of PM20D1 revealsN-acyl amino acid control of metabolism and nociception

(2018) Jonathan Z. Long et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic atlas of the human plasma proteome

(2018) Benjamin B. Sun et al.   NATURE

Co-regulatory networks of human serum proteins link genetics to disease

(2018) Valur Emilsson et al.   SCIENCE

2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2019

(2018)   DIABETES CARE

Growth differentiation factor 15 is positively associated with incidence of diabetes mellitus: the Malmö Diet and Cancer–Cardiovascular Cohort

(2018) Xue Bao et al.   DIABETOLOGIA

Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes

(2017) John F. O’Sullivan et al.   JOURNAL OF CLINICAL INVESTIGATION

Study of the expression and function of ACY1 in patients with colorectal cancer

(2017) Bing Yu et al.   Oncology Letters

Application of Large-Scale Aptamer-Based Proteomic Profiling to Planned Myocardial Infarctions

(2017) Jaison Jacob et al.   CIRCULATION

Genetic Architecture of the Cardiovascular Risk Proteome

(2017) Mark D. Benson et al.   CIRCULATION

Assessment of Variability in the SOMAscan Assay

(2017) Julián Candia et al.   Scientific Reports

PhenoScanner: a database of human genotype–phenotype associations

(2016) James R. Staley et al.   BIOINFORMATICS

Aptamer-Based Proteomic Profiling Reveals Novel Candidate Biomarkers and Pathways in Cardiovascular DiseaseClinical Perspective

(2016) Debby Ngo et al.   CIRCULATION

MASP1, THBS1, GPLD1 and ApoA-IV are novel biomarkers associated with prediabetes: the KORA F4 study

(2016) Christine von Toerne et al.   DIABETOLOGIA

Exome array analysis of ischaemic stroke: results from a southern Swedish study

(2016) M. Söderholm et al.   EUROPEAN JOURNAL OF NEUROLOGY

The progress and potential of proteomic biomarkers for type 1 diabetes in children

(2016) Robert Moulder et al.   Expert Review of Proteomics

Development and Validation of a Protein-Based Risk Score for Cardiovascular Outcomes Among Patients With Stable Coronary Heart Disease

(2016) Peter Ganz et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Proteomics reveals the effects of sustained weight loss on the human plasma proteome

(2016) Philipp E Geyer et al.   Molecular Systems Biology

An exome array study of the plasma metabolome

(2016) Eugene P. Rhee et al.   Nature Communications

Proteomic Biomarker Discovery in 1000 Human Plasma Samples with Mass Spectrometry

(2015) Ornella Cominetti et al.   JOURNAL OF PROTEOME RESEARCH

Large-scale serum protein biomarker discovery in Duchenne muscular dystrophy

(2015) Yetrib Hathout et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology

(2014) Martina Sattlecker et al.   Alzheimers & Dementia

Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

(2014) Claudia Giambartolomei et al.   PLoS Genetics

Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

(2013) Stephen Burgess et al.   GENETIC EPIDEMIOLOGY

2-Aminoadipic acid is a biomarker for diabetes risk

(2013) Thomas J. Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Serum aminoacylase-1 is a novel biomarker with potential prognostic utility for long-term outcome in patients with delayed graft function following renal transplantation

(2013) Matthew P. Welberry Smith et al.   KIDNEY INTERNATIONAL

The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective

(2013) Syed S Mahmood et al.   LANCET

Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium

(2013) Megan L. Grove et al.   PLoS One

Metabolite Profiling Identifies Pathways Associated With Metabolic Risk in Humans

(2012) Susan Cheng et al.   CIRCULATION

Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach

(2012) A. Floegel et al.   DIABETES

Insulin Resistance and Truncal Obesity as Important Determinants of the Greater Incidence of Diabetes in Indian Asians and African Caribbeans Compared With Europeans: The Southall And Brent REvisited (SABRE) cohort

(2012) T. Tillin et al.   DIABETES CARE

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

The molecular basis of aminoacylase 1 deficiency

(2011) Anke Sommer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans

(2011) Eugene P. Rhee et al.   JOURNAL OF CLINICAL INVESTIGATION

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

A Role for Glutamate Transporters in the Regulation of Insulin Secretion

(2011) Runhild Gammelsaeter et al.   PLoS One

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

(2010) Yun Li et al.   GENETIC EPIDEMIOLOGY

Complement control protein factor H: The good, the bad, and the inadequate

(2010) Viviana P. Ferreira et al.   MOLECULAR IMMUNOLOGY

GWAF: an R package for genome-wide association analyses with family data

(2009) Ming-Huei Chen et al.   BIOINFORMATICS

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Sex Hormone–Binding Globulin and Risk of Type 2 Diabetes in Women and Men

(2009) Eric L. Ding et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Genome-Wide Association Study of Pulmonary Function Measures in the Framingham Heart Study

(2009) Jemma B. Wilk et al.   PLoS Genetics

Risk Prediction of Cardiovascular Disease in Type 2 Diabetes: A risk equation from the Swedish National Diabetes Register

(2008) J. Cederholm et al.   DIABETES CARE

Both WFIKKN1 and WFIKKN2 Have High Affinity for Growth and Differentiation Factors 8 and 11

(2008) Katalin Kondás et al.   JOURNAL OF BIOLOGICAL CHEMISTRY