An integrated analysis identifies six molecular subtypes of pancreatic ductal adenocarcinoma revealing cellular and molecular landscape
出版年份 2023 全文链接
标题
An integrated analysis identifies six molecular subtypes of pancreatic ductal adenocarcinoma revealing cellular and molecular landscape
作者
关键词
-
出版物
CARCINOGENESIS
Volume -, Issue -, Pages -
出版商
Oxford University Press (OUP)
发表日期
2023-09-26
DOI
10.1093/carcin/bgad068
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Smad4 Deficiency Promotes Pancreatic Cancer Immunogenicity by Activating the Cancer‐Autonomous DNA‐Sensing Signaling Axis
- (2022) Wenjing Xiong et al. Advanced Science
- Loss of SMAD4 Is Associated With Poor Tumor Immunogenicity and Reduced PD-L1 Expression in Pancreatic Cancer
- (2022) Daniel R. Principe et al. Frontiers in Oncology
- Molecular Characterization of KRAS Wild-type Tumors in Patients with Pancreatic Adenocarcinoma
- (2022) Philip A. Philip et al. CLINICAL CANCER RESEARCH
- Distinct mechanisms of innate and adaptive immune regulation underlie poor oncologic outcomes associated with KRAS-TP53 co-alteration in pancreatic cancer
- (2022) Jashodeep Datta et al. ONCOGENE
- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- A Clinically Applicable 24-Protein Model for Classifying Risk Subgroups in Pancreatic Ductal Adenocarcinomas using Multiple Reaction Monitoring-Mass Spectrometry
- (2021) Minsoo Son et al. CLINICAL CANCER RESEARCH
- KRAS drives immune evasion in a genetic model of pancreatic cancer
- (2021) Irene Ischenko et al. Nature Communications
- Molecular Subtypes of Pancreatic Cancer: A Proteomics Approach
- (2021) Ravi Thakur et al. CLINICAL CANCER RESEARCH
- Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy
- (2021) Yujue Wang et al. CANCER CELL
- TP53 missense mutations in PDAC are associated with enhanced fibrosis and an immunosuppressive microenvironment
- (2021) Martino Maddalena et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Genome Sequence Archive Family: Toward Explosive Data Growth and Diverse Data Types
- (2021) Tingting Chen et al. GENOMICS PROTEOMICS & BIOINFORMATICS
- Integrating microarray-based spatial transcriptomics and single-cell RNA-seq reveals tissue architecture in pancreatic ductal adenocarcinomas
- (2020) Reuben Moncada et al. NATURE BIOTECHNOLOGY
- CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes
- (2020) Mirjana Efremova et al. Nature Protocols
- NK cells for cancer immunotherapy
- (2020) Noriko Shimasaki et al. NATURE REVIEWS DRUG DISCOVERY
- Immunotherapy for pancreatic cancer: A 2020 update
- (2020) Dimitrios Schizas et al. CANCER TREATMENT REVIEWS
- Pancreatic cancer
- (2020) Jonathan D Mizrahi et al. LANCET
- Challenges and Opportunities for Pancreatic Cancer Immunotherapy
- (2020) Adham S. Bear et al. CANCER CELL
- Molecular alterations and targeted therapy in pancreatic ductal adenocarcinoma
- (2020) Yunzhen Qian et al. Journal of Hematology & Oncology
- Integrative single-cell analysis
- (2019) Tim Stuart et al. NATURE REVIEWS GENETICS
- The International Cancer Genome Consortium Data Portal
- (2019) Junjun Zhang et al. NATURE BIOTECHNOLOGY
- Determining cell type abundance and expression from bulk tissues with digital cytometry
- (2019) Aaron M. Newman et al. NATURE BIOTECHNOLOGY
- Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma
- (2019) Junya Peng et al. CELL RESEARCH
- Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts
- (2019) Ela Elyada et al. Cancer Discovery
- Monalizumab: inhibiting the novel immune checkpoint NKG2A
- (2019) Thorbald van Hall et al. Journal for ImmunoTherapy of Cancer
- Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation
- (2018) Tathiane M. Malta et al. CELL
- Serum FBLN1 and STK31 as biomarkers of colorectal cancer and their ability to noninvasively differentiate colorectal cancer from benign polyps
- (2018) Mona Mohamed Watany et al. CLINICA CHIMICA ACTA
- ImmPort, toward repurposing of open access immunological assay data for translational and clinical research
- (2018) Sanchita Bhattacharya et al. Scientific Data
- Next Generation Immunotherapy for Pancreatic Cancer: DNA Vaccination is Seeking New Combo Partners
- (2018) Paola Cappello et al. Cancers
- Molecular Subtypes of Urothelial Bladder Cancer: Results from a Meta-cohort Analysis of 2411 Tumors
- (2018) Tuan Zea Tan et al. EUROPEAN UROLOGY
- Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells
- (2018) Pascale André et al. CELL
- Stratification of Pancreatic Ductal Adenocarcinomas Based on Tumor and Microenvironment Features
- (2018) Francesco Puleo et al. GASTROENTEROLOGY
- TRIB3 Interacts With β-Catenin and TCF4 to Increase Stem Cell Features of Colorectal Cancer Stem Cells and Tumorigenesis
- (2018) Fang Hua et al. GASTROENTEROLOGY
- Maftools: efficient and comprehensive analysis of somatic variants in cancer
- (2018) Anand Mayakonda et al. GENOME RESEARCH
- ArrayExpress update – from bulk to single-cell expression data
- (2018) Awais Athar et al. NUCLEIC ACIDS RESEARCH
- Pancreatic cancer cell lines as patient-derived avatars: genetic characterisation and functional utility
- (2017) Erik S Knudsen et al. GUT
- Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
- (2017) Daniel Öhlund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade
- (2017) Pornpimol Charoentong et al. Cell Reports
- Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma
- (2016) Willy Hugo et al. CELL
- Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation
- (2016) Ana C. Anderson et al. IMMUNITY
- The extracellular matrix: Tools and insights for the “omics” era
- (2016) Alexandra Naba et al. MATRIX BIOLOGY
- Genomic analyses identify molecular subtypes of pancreatic cancer
- (2016) Peter Bailey et al. NATURE
- Toward a Shared Vision for Cancer Genomic Data
- (2016) Robert L. Grossman et al. NEW ENGLAND JOURNAL OF MEDICINE
- The PRKD1 promoter is a target of the KRas-NF-κB pathway in pancreatic cancer
- (2016) Heike Döppler et al. Scientific Reports
- Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
- (2015) Evan Z. Macosko et al. CELL
- Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma
- (2015) Richard A Moffitt et al. NATURE GENETICS
- Anti-α-enolase antibody limits the invasion of myeloid-derived suppressor cells and attenuates their restraining effector T cell response
- (2015) Paola Cappello et al. OncoImmunology
- GSVA: gene set variation analysis for microarray and RNA-Seq data
- (2013) Sonja Hänzelmann et al. BMC BIOINFORMATICS
- Vaccination With ENO1 DNA Prolongs Survival of Genetically Engineered Mice With Pancreatic Cancer
- (2013) Paola Cappello et al. GASTROENTEROLOGY
- Inferring tumour purity and stromal and immune cell admixture from expression data
- (2013) Kosuke Yoshihara et al. Nature Communications
- NCBI GEO: archive for functional genomics data sets—update
- (2012) Tanya Barrett et al. NUCLEIC ACIDS RESEARCH
- clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
- (2012) Guangchuang Yu et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- MATH, a novel measure of intratumor genetic heterogeneity, is high in poor-outcome classes of head and neck squamous cell carcinoma
- (2012) Edmund A. Mroz et al. ORAL ONCOLOGY
- Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy
- (2011) Eric A Collisson et al. NATURE MEDICINE
- ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking
- (2010) Matthew D. Wilkerson et al. BIOINFORMATICS
- β-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice
- (2010) John P. Morris et al. JOURNAL OF CLINICAL INVESTIGATION
- Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
- (2010) J. H. Taube et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Merging two gene-expression studies via cross-platform normalization
- (2008) Andrey A. Shabalin et al. BIOINFORMATICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started