Fiber chromatographic enabled process intensification increases monoclonal antibody product yield

Single‐stage chromatographic clarification of Chinese Hamster Ovary cell harvest reduces cost of protein production

(2023) Brian O'Mara et al.   BIOTECHNOLOGY PROGRESS

Predictive scaling of fiber‐based protein A capture chromatography using mechanistic modeling

(2023) Tobias Hahn et al.   BIOTECHNOLOGY AND BIOENGINEERING

Comparative Evaluation of Commercial Protein A Membranes for the Rapid Purification of Antibodies

(2023) Joshua Osuofa et al.   Membranes

Recent development and application of membrane chromatography

(2022) Jing Chen et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

End to End Collaboration to Transform Biopharmaceutical Development and Manufacturing

(2021) John Erickson et al.   BIOTECHNOLOGY AND BIOENGINEERING

Improving mAb capture productivity on batch and continuous downstream processing using nanofiber PrismA adsorbents

(2021) Ryan R. Davis et al.   JOURNAL OF BIOTECHNOLOGY

Orthogonal pre-use and post-use efficiency testing for single-use anion exchange chromatography

(2021) Jonathan F. Hester et al.   JOURNAL OF CHROMATOGRAPHY A

Removing a single-arm species by Fibro PrismA in purifying an asymmetric IgG-like bispecific antibody

(2021) Ting Zhang et al.   PROTEIN EXPRESSION AND PURIFICATION

Identification and tracking of problematic host cell proteins removed by a synthetic, highly functionalized nonwoven media in downstream bioprocessing of monoclonal antibodies

(2019) S. Gilgunn et al.   JOURNAL OF CHROMATOGRAPHY A

Impact of depth filtration on disulfide bond reduction during downstream processing of monoclonal antibodies from CHO cell cultures

(2019) Brian O'Mara et al.   BIOTECHNOLOGY AND BIOENGINEERING

Enhancing Protein A Performance in mAb Processing: A Method to Reduce and Rapidly Evaluate Host Cell DNA Levels During Primary Clarification

(2019) K.C. Koehler et al.   BIOTECHNOLOGY PROGRESS

Comparison of membrane chromatography devices in laboratory-scale preparative flow-through separation of a recombinant protein

(2018) Pedram Madadkar et al.   SEPARATION SCIENCE AND TECHNOLOGY

Effects of bed compression on protein separation on gel filtration chromatography at bench and pilot scale

(2017) Darryl YC Kong et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Advance chromatin extraction improves capture performance of protein A affinity chromatography

(2016) Rui Nian et al.   JOURNAL OF CHROMATOGRAPHY A

A mechanistic model of ion-exchange chromatography on polymer fiber stationary phases

(2016) Johannes Winderl et al.   JOURNAL OF CHROMATOGRAPHY A

Development of adsorptive hybrid filters to enable two-step purification of biologics

(2016) Nripen Singh et al.   mAbs

Evaluation of a structural mechanics model to predict the effect of inserts in the bed support of chromatographic columns

(2015) Spyridon Gerontas et al.   CHEMICAL ENGINEERING SCIENCE

Fabricating electrospun cellulose nanofibre adsorbents for ion-exchange chromatography

(2015) Stewart R. Dods et al.   JOURNAL OF CHROMATOGRAPHY A

Nonspecific interactions of chromatin with immunoglobulin G and protein A, and their impact on purification performance

(2014) Pete Gagnon et al.   JOURNAL OF CHROMATOGRAPHY A

Protein a chromatography at high titers

(2013) Venkatesh Natarajan et al.   BIOTECHNOLOGY AND BIOENGINEERING

A monolith purification process for virus-like particles from yeast homogenate

(2011) Claire S. Burden et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES