Synthesis and biological evaluation of indane-based fluorescent probes for detection of amyloid-β aggregates in Alzheimer’s disease

Strategic Design of Amyloid-β Species Fluorescent Probes for Alzheimer’s Disease

(2022) Dunyan Su et al.   ACS Chemical Neuroscience

PET molecular imaging for pathophysiological visualization in Alzheimer’s disease

(2022) Jing Wang et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

In Vivo Brain Imaging of Amyloid-β Aggregates in Alzheimer’s Disease with a Near-Infrared Fluorescent Probe

(2021) Jian Wu et al.   ACS Sensors

Strategies for Structural Modification of Small Molecules to Improve Blood–Brain Barrier Penetration: A Recent Perspective

(2021) Baichen Xiong et al.   JOURNAL OF MEDICINAL CHEMISTRY

Potent therapeutic targets for treatment of Alzheimer's disease: Amyloid degrading enzymes

(2021) Hang Choi et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Redox Properties of Small Molecules Essential for Multiple Reactivities with Pathological Factors in Alzheimer's Disease

(2021) Mingeun Kim et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Thiophene‐π‐Cyanoacetamides Show Intense and Tau‐selective Turn‐on Fluorescence in the Near‐Infrared Region

(2021) Yeonji Oh et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Synthesis and evaluation of curcumin-based near-infrared fluorescent probes for the in vivo optical imaging of amyloid-β plaques

(2021) Yong Dae Park et al.   BIOORGANIC CHEMISTRY

Evaluation of N, O-Benzamide difluoroboron derivatives as near-infrared fluorescent probes to detect β-amyloid and tau tangles

(2021) Yimin Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Rational Design of Near-Infrared AIE-Active Probes: In Situ Mapping of Amyloid-β Plaques with Ultra-Sensitivity and High-Fidelity

(2019) Wei Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Frontiers in Probing Alzheimer’s Disease Biomarkers with Fluorescent Small Molecules

(2019) Yong Woong Jun et al.   ACS Central Science

Development of Near-Infrared Fluorescent Probes for Use in Alzheimer’s Disease Diagnosis

(2019) Jian Yang et al.   BIOCONJUGATE CHEMISTRY

Biological applications of near infrared fluorescence dye probes in monitoring Alzheimer’s disease

(2019) Yusif Issahak Gyasi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

In vivo molecular imaging of neuroinflammation in Alzheimer's disease

(2018) Aisling Chaney et al.   JOURNAL OF NEUROCHEMISTRY

Fibril structure of amyloid-β(1–42) by cryo–electron microscopy

(2017) Lothar Gremer et al.   SCIENCE

A Smart Near-Infrared Fluorescence Probe for Selective Detection of Tau Fibrils in Alzheimer’s Disease

(2016) Yujin Seo et al.   ACS Chemical Neuroscience

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

Diagnostic accuracy of 18F amyloid PET tracers for the diagnosis of Alzheimer’s disease: a systematic review and meta-analysis

(2015) Elizabeth Morris et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Towards early diagnosis in Alzheimer disease

(2015) Agneta Nordberg   Nature Reviews Neurology

Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer’s disease

(2015) Xueli Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer's disease

(2015) Colin L. Masters et al.   Nature Reviews Disease Primers

Evaluation of molecules based on the electron donor–acceptor architecture as near-infrared β-amyloidal-targeting probes

(2014) Hualong Fu et al.   CHEMICAL COMMUNICATIONS

Smart Near-Infrared Fluorescence Probes with Donor–Acceptor Structure for in Vivo Detection of β-Amyloid Deposits

(2014) Mengchao Cui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

2,2′-Azobis(2-methylpropionitrile)-Mediated Alkyne Hydrostannylation: Reaction Mechanism

(2013) Martins S. Oderinde et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Turn-On Fluorogenic Probes for the Selective and Quantitative Detection of the Cyanide Anion from Natural Sources

(2013) Teresa Gómez et al.   Chemistry-An Asian Journal

[18F]Flutemetamol amyloid-beta PET imaging compared with [11C]PIB across the spectrum of Alzheimer’s disease

(2013) Shizuo Hatashita et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

BODIPY-Based Molecular Probe for Imaging of Cerebral β-Amyloid Plaques

(2012) Masahiro Ono et al.   ACS Chemical Neuroscience

The Amyloid Beta Peptide: A Chemist’s Perspective. Role in Alzheimer’s and Fibrillization

(2012) I. W. Hamley   CHEMICAL REVIEWS

The influence of lipophilicity in drug discovery and design

(2012) John A Arnott et al.   Expert Opinion on Drug Discovery

Total Synthesis of a Marine Alkaloid—Rigidin E

(2012) Banpeng Cao et al.   Marine Drugs

Brain Amyloid Imaging — FDA Approval of Florbetapir F18 Injection

(2012) Lucie Yang et al.   NEW ENGLAND JOURNAL OF MEDICINE

The β-Amyloid Hypothesis in Alzheimer's Disease: Seeing Is Believing

(2012) Hank F. Kung   ACS Medicinal Chemistry Letters

Binding Modes of Thioflavin T Molecules to Prion Peptide Assemblies Identified by Using Scanning Tunneling Microscopy

(2011) Xiaobo Mao et al.   ACS Chemical Neuroscience

Non-invasive imaging in experimental medicine for drug development

(2011) Paul M Matthews et al.   CURRENT OPINION IN PHARMACOLOGY

Cyanoacetamide Multicomponent Reaction (I): Parallel Synthesis Of Cyanoacetamides

(2009) Kan Wang et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Binding Modes of Thioflavin-T to the Single-Layer β-Sheet of the Peptide Self-Assembly Mimics

(2009) Chun Wu et al.   JOURNAL OF MOLECULAR BIOLOGY

Design, Synthesis, and Testing of Difluoroboron-Derivatized Curcumins as Near-Infrared Probes for in Vivo Detection of Amyloid-β Deposits

(2009) Chongzhao Ran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alzheimer's disease

(2009) Lennart Mucke   NATURE

Blood–brain barrier permeability considerations for CNS-targeted compound library design

(2008) Stephen A Hitchcock   CURRENT OPINION IN CHEMICAL BIOLOGY