Estrogen Attenuates Diethylnitrosamine-Induced Hepatocellular Carcinoma in Female Rats <i>via</i> Modulation of Estrogen Receptor/FASN/CD36/IL-6 Axis

Tilianin Protects against Nonalcoholic Fatty Liver Disease in Early Obesity Mice

(2023) Sen-Mao Xu et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The Natural Estrogen Receptor Beta Agonist Silibinin as a Promising Therapeutic Tool in Diffuse Large B-cell Lymphoma

(2022) ELENA ORTONA et al.   ANTICANCER RESEARCH

Metabolic Reprogramming in Cancer Cells: Emerging Molecular Mechanisms and Novel Therapeutic Approaches

(2022) Carla Navarro et al.   Pharmaceutics

Estrogen Receptor-α Suppresses Liver Carcinogenesis and Establishes Sex-Specific Gene Expression

(2021) Mara H. O’Brien et al.   Cancers

Therapeutic Value of Estrogen Receptor α in Hepatocellular Carcinoma Based on Molecular Mechanisms

(2021) Xiangzhe Meng et al.   Journal of Clinical and Translational Hepatology

Curcumae Ameliorates Diethylnitrosamine-Induced Hepatocellular Carcinoma via Alteration of Oxidative Stress, Inflammation and Gut Microbiota

(2021) Yunyan Zhang et al.   Journal of Inflammation Research

CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing

(2021) Han Zeng et al.   Molecular Metabolism

Antrodan Alleviates High-Fat and High-Fructose Diet-Induced Fatty Liver Disease in C57BL/6 Mice Model via AMPK/Sirt1/SREBP-1c/PPARγ Pathway

(2020) Charng-Cherng Chyau et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The threshold of alpha-fetoprotein (AFP) for the diagnosis of hepatocellular carcinoma: A systematic review and meta-analysis

(2020) Jiaxin Zhang et al.   PLoS One

Fatty Acid Synthase: An Emerging Target in Cancer

(2020) Chee Wai Fhu et al.   MOLECULES

Inhibitory effect of 17β‑estradiol on triglyceride synthesis in skeletal muscle cells is dependent on ESR1 and not ESR2

(2019) Quan Liu et al.   Molecular Medicine Reports

Hepatocellular Carcinoma

(2019) Augusto Villanueva   NEW ENGLAND JOURNAL OF MEDICINE

Identification and characterization of sexual dimorphism‑linked gene expression profile in hepatocellular carcinoma

(2019) Yuchao Wu et al.   ONCOLOGY REPORTS

New pharmacological effect of fulvestrant to prevent oxaliplatin-induced neurodegeneration and mechanical allodynia in rats

(2018) Shota Yamamoto et al.   INTERNATIONAL JOURNAL OF CANCER

Interference With Coagulation Cascade as a Novel Approach to Counteract Cisplatin-Induced Acute Tubular Necrosis; an Experimental Study in Rats

(2018) Mohamed G. Ewees et al.   Frontiers in Pharmacology

Lipid Metabolic Reprogramming in Hepatocellular Carcinoma

(2018) Hayato Nakagawa et al.   Cancers

Menopausal hormone therapy and cancer risk: An overestimated risk?

(2017) Johanna Simin et al.   EUROPEAN JOURNAL OF CANCER

Estrogen receptor expression in chronic hepatitis C and hepatocellular carcinoma pathogenesis

(2017) Janaki K Iyer et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Feasibility and antitumor efficacy in vivo, of simultaneously targeting glycolysis, glutaminolysis and fatty acid synthesis using lonidamine, 6-diazo-5-oxo-L-norleucine and orlistat in colon cancer

(2017) Diana Cervantes-Madrid et al.   Oncology Letters

Hepatic estrogen receptor α is critical for regulation of gluconeogenesis and lipid metabolism in males

(2017) Shuiqing Qiu et al.   Scientific Reports

Antiestrogen use reduces risk of cervical neoplasia in breast cancer patients: a population-based study

(2016) Chia-Jung Hsieh et al.   Oncotarget

Silymarin and hepatocellular carcinoma

(2015) Jeanetta K. Mastron et al.   ANTI-CANCER DRUGS

Albumin-to-Alkaline Phosphatase Ratio: A Novel Prognostic Index for Hepatocellular Carcinoma

(2015) Anthony W. H. Chan et al.   DISEASE MARKERS

Synergistic effect of curcumin and piperine in suppression of DENA-induced hepatocellular carcinoma in rats

(2015) Vikram Patial et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Obesity Early in Adulthood Increases Risk but Does Not Affect Outcomes of Hepatocellular Carcinoma

(2015) Manal M. Hassan et al.   GASTROENTEROLOGY

Safety and blood sample volume and quality of a refined retro-orbital bleeding technique in rats using a lateral approach

(2014) Ashish Sharma et al.   LAB ANIMAL

Mechanism of Orlistat Hydrolysis by the Thioesterase of Human Fatty Acid Synthase

(2014) Valerie E. Fako et al.   ACS Catalysis

Cellular Fatty Acid Metabolism and Cancer

(2013) Erin Currie et al.   Cell Metabolism

Metformin Prevents Liver Tumorigenesis by Inhibiting Pathways Driving Hepatic Lipogenesis

(2012) K. Bhalla et al.   Cancer Prevention Research

Metformin decreases hepatocellular carcinoma risk in a dose-dependent manner: population-based and in vitro studies

(2012) Hsiao-Ping Chen et al.   GUT

Targeting androgen receptor in bone marrow mesenchymal stem cells leads to better transplantation therapy efficacy in liver cirrhosis

(2012) Chiung-Kuei Huang et al.   HEPATOLOGY

Estrogen Represses Hepatocellular Carcinoma (HCC) Growth via Inhibiting Alternative Activation of Tumor-associated Macrophages (TAMs)

(2012) Weiwei Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The integral role of mTOR in lipid metabolism

(2011) Ghada A. Soliman   CELL CYCLE

Gender Disparity of Hepatocellular Carcinoma: The Roles of Sex Hormones

(2010) Shiou-Hwei Yeh et al.   ONCOLOGY

Fructose induced lipogenesis: from sugar to fat to insulin resistance

(2010) Varman T. Samuel   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Fatty Acid Synthase Inhibition by Amentoflavone Induces Apoptosis and Antiproliferation in Human Breast Cancer Cells

(2009) Jin Sun Lee et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Silymarin, the antioxidant component and Silybum marianum extracts prevent liver damage

(2009) E. Shaker et al.   FOOD AND CHEMICAL TOXICOLOGY

Role of free radicals in liver diseases

(2009) Pablo Muriel   Hepatology International

Gender Disparity of Hepatic Lipid Homoeostasis Regulated by the Circadian Clock

(2009) X. Yang et al.   JOURNAL OF BIOCHEMISTRY

An Altered Pattern of Liver Apolipoprotein A-I Isoforms Is Implicated in Male Chronic Hepatitis B Progression

(2009) Fu Yang et al.   JOURNAL OF PROTEOME RESEARCH

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Markedly Blunted Metabolic Effects of Fructose in Healthy Young Female Subjects Compared With Male Subjects

(2008) C. Couchepin et al.   DIABETES CARE

Inhibition of Fatty-acid Synthase Induces Caspase-8-mediated Tumor Cell Apoptosis by Up-regulating DDIT4

(2008) Lynn M. Knowles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY