SENP1 knockdown-mediated CTCF SUMOylation enhanced its stability and alleviated lipopolysaccharide-evoked inflammatory injury in human lung fibroblasts via regulation of FOXA2 transcription

CCCTC-binding factor-mediated microRNA-340-5p suppression aggravates myocardial injury in rats with severe acute pancreatitis through activation of the HMGB1/TLR4 axis

(2022) Yazhou Gao et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

SUMO mediated regulation of transcription factors as a mechanism for transducing environmental cues into cellular signaling in plants

(2021) Dipan Roy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dynamic regulation of CTCF stability and sub-nuclear localization in response to stress

(2021) Bettina J. Lehman et al.   PLoS Genetics

Increased SUMOylation of TCF21 improves its stability and function in human endometriotic stromal cells

(2021) Jingwen Zhu et al.   BIOLOGY OF REPRODUCTION

SUMOylation modulates the stability and function of PI3K-p110β

(2021) Ahmed El Motiam et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Overexpression of FOXA2 attenuates cigarette smoke-induced cellular senescence and lung inflammation through inhibition of the p38 and Erk1/2 MAPK pathways

(2021) Yixiu Tao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

O‐GlcNAcylation promotes the migratory ability of hepatocellular carcinoma cells via regulating FOXA2 stability and transcriptional activity

(2021) Huang Huang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Gambogic acid protects LPS-induced apoptosis and inflammation in a cell model of neonatal pneumonia through the regulation of TrkA/Akt signaling pathway

(2021) Xu Gao et al.   BMC Pharmacology & Toxicology

Hypoxia activates SUMO-1-HIF-1α signaling pathway to upregulate pro-inflammatory cytokines and permeability in human tonsil epithelial cells

(2021) Yan Lin et al.   LIFE SCIENCES

Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer

(2021) Kenichi Miyata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRIM28 SUMOylates and stabilizes NLRP3 to facilitate inflammasome activation

(2021) Ying Qin et al.   Nature Communications

Liver-Specific Deletion of Mouse CTCF Leads to Hepatic Steatosis via Augmented PPARγ Signaling

(2021) Yeeun Choi et al.   Cellular and Molecular Gastroenterology and Hepatology

Long noncoding RNA SNHG4 remits lipopolysaccharide-engendered inflammatory lung damage by inhibiting METTL3 – Mediated m6A level of STAT2 mRNA

(2021) Si-Xiu Li et al.   MOLECULAR IMMUNOLOGY

SUMOylation of the transcription factor ZFHX3 at Lys-2806 requires SAE1, UBC9, and PIAS2 and enhances its stability and function in cell proliferation

(2020) Rui Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SUMOylation controls the neurodevelopmental function of the transcription factor Zbtb20

(2020) Silvia Ripamonti et al.   JOURNAL OF NEUROCHEMISTRY

Inactivation of FOXA2 by Respiratory Bacterial Pathogens and Dysregulation of Pulmonary Mucus Homeostasis

(2020) Woosuk Choi et al.   Frontiers in Immunology

CTCF promotes colorectal cancer cell proliferation and chemotherapy resistance to 5-FU via the P53-Hedgehog axis

(2020) Qiuhua Lai et al.   Aging-US

Protein sumoylation with SUMO1 promoted by Pin1 in glioma stem cells augments glioblastoma malignancy

(2020) Aili Zhang et al.   NEURO-ONCOLOGY

A Critical Role for ISGylation, Ubiquitination and, SUMOylation in Brain Damage: Implications for Neuroprotection

(2020) Venkata Prasuja Nakka et al.   NEUROCHEMICAL RESEARCH

SUMOylation of MCL1 protein enhances its stability by regulating the ubiquitin-proteasome pathway

(2020) Shujing Li et al.   CELLULAR SIGNALLING

LncRNA UCA1 remits LPS ‐engendered inflammatory damage through deactivation of miR ‐499b‐5p/ TLR4 axis

(2020) Yan‐jun Zhao et al.   IUBMB LIFE

Long noncoding RNA SNHG16 targets miR-146a-5p/CCL5 to regulate LPS-induced WI-38 cell apoptosis and inflammation in acute pneumonia

(2019) Zhiming Zhou et al.   LIFE SCIENCES

Long noncoding RNA MIAT2 alleviates lipopolysaccharide‐induced inflammatory damage in WI‐38 cells by sponging microRNA‐15

(2019) Hong Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

CTCF inhibits endoplasmic reticulum stress and apoptosis in cardiomyocytes by upregulating RYR2 via inhibiting S100A1

(2019) Zhu Zeng et al.   LIFE SCIENCES

SENP1 attenuates the liver fibrosis through down-regulating the expression of SMAD2

(2018) Linshi Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SUMO protease SENP1 deSUMOylates and stabilizes c-Myc

(2018) Xiao-Xin Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abnormal Microglia and Enhanced Inflammation-Related Gene Transcription in Mice with Conditional Deletion ofCtcfinCamk2a-Cre-Expressing Neurons.

(2017) Bryan E. McGill et al.   JOURNAL OF NEUROSCIENCE

Developmental lung expression and transcriptional regulation of Claudin-6 by TTF-1, Gata-6, and FoxA2

(2014) Felix R Jimenez et al.   RESPIRATORY RESEARCH

Foxa2 Regulates Leukotrienes to Inhibit Th2-mediated Pulmonary Inflammation

(2013) Xiaoju Tang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

De-SUMOylation of CCCTC Binding Factor (CTCF) in Hypoxic Stress-induced Human Corneal Epithelial Cells

(2012) Jie Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Forkhead Box Protein A2 (FOXA2) Protein Stability and Activity Are Regulated by Sumoylation

(2012) Narasimhaswamy S. Belaguli et al.   PLoS One

SUMO-specific protease 1 regulates the in vitro and in vivo growth of colon cancer cells with the upregulated expression of CDK inhibitors

(2011) Ying Xu et al.   CANCER LETTERS

Sumoylation modulates a domain in CTCF that activates transcription and decondenses chromatin

(2010) Neal S. Kitchen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY