The extracellular chaperone clusterin prevents primary and secondary nucleation of an amyloidogenic variant of β2-microglobulin

Are casein micelles extracellular condensates formed by liquid‐liquid phase separation?

(2022) Attila Horvath et al.   FEBS LETTERS

Clusterin Binding Modulates the Aggregation and Neurotoxicity of Amyloid-β(1–42)

(2022) Yun-Mi Kim et al.   MOLECULAR NEUROBIOLOGY

Macromolecular crowding and supersaturation protect hemodialysis patients from the onset of dialysis-related amyloidosis

(2022) Kichitaro Nakajima et al.   Nature Communications

Secondary nucleation in amyloid formation

(2018) Mattias Törnquist et al.   CHEMICAL COMMUNICATIONS

Clusterin: full-length protein and one of its chains show opposing effects on cellular lipid accumulation

(2017) Suvarsha Rao Matukumalli et al.   Scientific Reports

Co-fibrillogenesis of Wild-type and D76N β2-Microglobulin

(2016) Antonino Natalello et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systemic Amyloidosis: Lessons from β2-Microglobulin

(2015) Monica Stoppini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

On the lag phase in amyloid fibril formation

(2015) Paolo Arosio et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Amyloid Fibres: Inert End-Stage Aggregates or Key Players in Disease?

(2015) Kevin W. Tipping et al.   TRENDS IN BIOCHEMICAL SCIENCES

Rare Individual Amyloid-β Oligomers Act on Astrocytes to Initiate Neuronal Damage

(2014) Priyanka Narayan et al.   BIOCHEMISTRY

Small heat-shock proteins: important players in regulating cellular proteostasis

(2014) Teresa M. Treweek et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The amyloid state and its association with protein misfolding diseases

(2014) Tuomas P. J. Knowles et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Expression and Purification of Chaperone-Active Recombinant Clusterin

(2014) Rebecca A. Dabbs et al.   PLoS One

Extracellular Chaperones and Proteostasis

(2013) Amy R. Wyatt et al.   Annual Review of Biochemistry

Monitoring the Interaction between β2-Microglobulin and the Molecular Chaperone αB-crystallin by NMR and Mass Spectrometry

(2013) Gennaro Esposito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Extracellular Chaperone Haptoglobin Prevents Serum Fatty Acid-promoted Amyloid Fibril Formation of β2-Microglobulin, Resistance to Lysosomal Degradation, and Cytotoxicity

(2013) Abdullah Sultan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure, Folding Dynamics, and Amyloidogenesis of D76N β2-Microglobulin

(2013) P. Patrizia Mangione et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduction of conformational mobility and aggregation in W60G β2-microglobulin: assessment by15N NMR relaxation

(2013) Devrim Gümral et al.   MAGNETIC RESONANCE IN CHEMISTRY

Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism

(2013) S. I. A. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid-β Oligomers are Sequestered by both Intracellular and Extracellular Chaperones

(2012) Priyanka Narayan et al.   BIOCHEMISTRY

Avoiding the oligomeric state: αB-crystallin inhibits fragmentation and induces dissociation of apolipoprotein C-II amyloid fibrils

(2012) Katrina J. Binger et al.   FASEB JOURNAL

Hereditary Systemic Amyloidosis Due to Asp76Asn Variant β2-Microglobulin

(2012) Sophie Valleix et al.   NEW ENGLAND JOURNAL OF MEDICINE

Binding of the Molecular Chaperone αB-Crystallin to Aβ Amyloid Fibrils Inhibits Fibril Elongation

(2011) Sarah L. Shammas et al.   BIOPHYSICAL JOURNAL

Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions

(2011) Heidi Olzscha et al.   CELL

Plasma Clusterin and the Risk of Alzheimer Disease

(2011) Elisabeth M. C. Schrijvers   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Inhibition of β2-Microglobulin Amyloid Fibril Formation by α2-Macroglobulin

(2011) Daisaku Ozawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational Conversion during Amyloid Formation at Atomic Resolution

(2011) Timo Eichner et al.   MOLECULAR CELL

Small heat shock proteins and α-crystallins: dynamic proteins with flexible functions

(2011) Eman Basha et al.   TRENDS IN BIOCHEMICAL SCIENCES

Association of Plasma Clusterin Concentration With Severity, Pathology, and Progression in Alzheimer Disease

(2010) Madhav Thambisetty et al.   ARCHIVES OF GENERAL PSYCHIATRY

The Interaction of αB-Crystallin with Mature α-Synuclein Amyloid Fibrils Inhibits Their Elongation

(2010) Christopher A. Waudby et al.   BIOPHYSICAL JOURNAL

Residue-Specific, Real-Time Characterization of Lag-Phase Species and Fibril Growth During Amyloid Formation: A Combined Fluorescence and IR Study of p-Cyanophenylalanine Analogs of Islet Amyloid Polypeptide

(2010) Peter Marek et al.   JOURNAL OF MOLECULAR BIOLOGY

Biological and Chemical Approaches to Diseases of Proteostasis Deficiency

(2009) Evan T. Powers et al.   Annual Review of Biochemistry

Fibril Fragmentation Enhances Amyloid Cytotoxicity

(2009) Wei-Feng Xue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Converging concepts of protein folding in vitro and in vivo

(2009) F Ulrich Hartl et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An Analytical Solution to the Kinetics of Breakable Filament Assembly

(2009) T. P. J. Knowles et al.   SCIENCE

Amyloidogenesis in its biological environment: challenging a fundamental issue in protein misfolding diseases

(2008) Vittorio Bellotti et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Potential roles of abundant extracellular chaperones in the control of amyloid formation and toxicity

(2007) Mark R. Wilson et al.   Molecular BioSystems

The solution structure of human β2-microglobulin reveals the prodromes of its amyloid transition

(2002) Giuliana Verdone et al.   PROTEIN SCIENCE