The Origin and Early Evolution of Life: Homochirality Emergence in Prebiotic Environments

Extraterrestrial amino acids and amines identified in asteroid Ryugu samples returned by the Hayabusa2 mission

(2023) Eric T. Parker et al.   GEOCHIMICA ET COSMOCHIMICA ACTA

Soluble organic molecules in samples of the carbonaceous asteroid (162173) Ryugu

(2023) Hiroshi Naraoka et al.   SCIENCE

Synthesis of Phospholipids Under Plausible Prebiotic Conditions and Analogies with Phospholipid Biochemistry for Origin of Life Studies

(2022) Michele Fiore et al.   ASTROBIOLOGY

Spontaneous Formation of Functional Structures in Messy Environments

(2022) Christian Mayer   Life-Basel

On the Origin of Sugar Handedness: Facts, Hypotheses and Missing Links-A Review

(2022) R. Fernando Martínez et al.   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

On the origins of life’s homochirality: Inducing enantiomeric excess with spin-polarized electrons

(2022) S. Furkan Ozturk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical Models for Understanding the Emergence of Homo-Chirality of Phospholipids for Origin of Life Studies

(2022) Fryni Skorda et al.   Symmetry-Basel

Prebiotic Organic Chemistry of Formamide and the Origin of Life in Planetary Conditions: What We Know and What Is the Future

(2021) Bruno Mattia Bizzarri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chromatophores efficiently promote light-driven ATP synthesis and DNA transcription inside hybrid multicompartment artificial cells

(2021) Emiliano Altamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing the Role of Chirality in Phospholipid Membranes

(2021) Hannah S. Martin et al.   CHEMBIOCHEM

Racemate Resolution of Alanine and Leucine on Homochiral Quartz, and Its Alteration by Strong Radiation Damage

(2021) Adrien D. Garcia et al.   Life-Basel

Center for Astrobiology: Toward the RNA-World in the Interstellar Medium—Detection of Urea and Search of 2-Amino-oxazole and Simple Sugars

(2020) Izaskun Jiménez-Serra et al.   ASTROBIOLOGY

Demystifying the asymmetry-amplifying, autocatalytic behaviour of the Soai reaction through structural, mechanistic and computational studies

(2020) Soumitra V. Athavale et al.   Nature Chemistry

Racemic Phospholipids for Origin of Life Studies

(2020) Emiliano Altamura et al.   Symmetry-Basel

Symmetry Breaking of Phospholipids

(2020) Michele Fiore et al.   Symmetry-Basel

The Origin of Biological Homochirality

(2019) Donna G. Blackmond   Cold Spring Harbor Perspectives in Biology

Length-Selective Synthesis of Acylglycerol-Phosphates through Energy-Dissipative Cycling

(2019) Claudia Bonfio et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and breakdown of universal metabolic precursors promoted by iron

(2019) Kamila B. Muchowska et al.   NATURE

Role of Asymmetric Autocatalysis in the Elucidation of Origins of Homochirality of Organic Compounds

(2019) Kenso Soai et al.   Symmetry-Basel

Autocatalytic Models for the Origin of Biological Homochirality

(2019) Donna G. Blackmond   CHEMICAL REVIEWS

A Hydrothermal-Sedimentary Context for the Origin of Life

(2018) F. Westall et al.   ASTROBIOLOGY

UV-light-driven prebiotic synthesis of iron–sulfur clusters

(2017) Claudia Bonfio et al.   Nature Chemistry

Hydroxyapatite: catalyst for a one-pot pentose formation

(2017) K. Usami et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Prebiotic stereoselective synthesis of purine and noncanonical pyrimidine nucleotide from nucleobases and phosphorylated carbohydrates

(2017) Hyo-Joong Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comment on “Ribose and related sugars from ultraviolet irradiation of interstellar ice analogs”

(2017) Jun Kawai   SCIENCE

Reaction: A New Genesis for Origins Research?

(2017) Leroy Cronin   Chem

Prebiotic Systems Chemistry: Complexity Overcoming Clutter

(2017) Saidul Islam et al.   Chem

Opinion: Studies on the origin of life — the end of the beginning

(2017) John D. Sutherland   Nature Reviews Chemistry

Mixed Anhydride Intermediates in the Reaction of 5(4H )-Oxazolones with Phosphate Esters and Nucleotides

(2016) Ziwei Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Autocatalytic, bistable, oscillatory networks of biologically relevant organic reactions

(2016) Sergey N. Semenov et al.   NATURE

A prebiotically plausible synthesis of pyrimidine β-ribonucleosides and their phosphate derivatives involving photoanomerization

(2016) Jianfeng Xu et al.   Nature Chemistry

Prebiotic chemistry and atmospheric warming of early Earth by an active young Sun

(2016) V. S. Airapetian et al.   Nature Geoscience

Enantiomer excesses of rare and common sugar derivatives in carbonaceous meteorites

(2016) George Cooper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribose and related sugars from ultraviolet irradiation of interstellar ice analogs

(2016) C. Meinert et al.   SCIENCE

The Origin of Life-Out of the Blue

(2015) John D. Sutherland   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Strategy for Origins of Life Research

(2015) Caleb Scharf et al.   ASTROBIOLOGY

Abiotic Regioselective Phosphorylation of Adenosine with Borate in Formamide

(2015) Yoshihiro Furukawa et al.   ASTROBIOLOGY

Lipid Chirality Revisited: A Change in Lipid Configuration Transforms Membrane-Bound Protein Domains

(2015) Frederic Eghiaian   BIOPHYSICAL JOURNAL

Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism

(2015) Bhavesh H. Patel et al.   Nature Chemistry

Molecular Chirality in Meteorites and Interstellar Ices, and the Chirality Experiment on Board the ESA Cometary Rosetta Mission

(2014) Iuliia Myrgorodska et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photonenergy-Controlled Symmetry Breaking with Circularly Polarized Light

(2013) Cornelia Meinert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New insights into prebiotic chemistry from Stanley Miller's spark discharge experiments

(2013) Jeffrey L. Bada   CHEMICAL SOCIETY REVIEWS

On the Origin of Single Chirality of Amino Acids and Sugars in Biogenesis

(2012) Jason E. Hein et al.   ACCOUNTS OF CHEMICAL RESEARCH

Asphalt, Water, and the Prebiotic Synthesis of Ribose, Ribonucleosides, and RNA

(2012) Steven A. Benner et al.   ACCOUNTS OF CHEMICAL RESEARCH

The early evolution of lipid membranes and the three domains of life

(2012) Jonathan Lombard et al.   NATURE REVIEWS MICROBIOLOGY

Synthesis of Carbohydrates in Mineral-Guided Prebiotic Cycles

(2011) Hyo-Joong Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

From Water and Ions to Crowded Biomacromolecules: In Vivo Structuring of a Prokaryotic Cell

(2011) J. Spitzer   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

A route to enantiopure RNA precursors from nearly racemic starting materials

(2011) Jason E. Hein et al.   Nature Chemistry

Primordial synthesis of amines and amino acids in a 1958 Miller H2S-rich spark discharge experiment

(2011) E. T. Parker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autonomy in evolution: from minimal to complex life

(2011) Kepa Ruiz-Mirazo et al.   SYNTHESE

Chemoselective Multicomponent One-Pot Assembly of Purine Precursors in Water

(2010) Matthew W. Powner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

L-amino acids catalyze the formation of an excess of D-glyceraldehyde, and thus of other D sugars, under credible prebiotic conditions

(2010) R. Breslow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis of S-glycosyl amino acids and S-glycopeptides via photoinduced click thiol–ene coupling

(2010) Michele Fiore et al.   TETRAHEDRON LETTERS

Planetary Organic Chemistry and the Origins of Biomolecules

(2010) S. A. Benner et al.   Cold Spring Harbor Perspectives in Biology

Primitive Genetic Polymers

(2010) A. E. Engelhart et al.   Cold Spring Harbor Perspectives in Biology

The Origin of Biological Homochirality

(2010) D. G. Blackmond   Cold Spring Harbor Perspectives in Biology

Chiral Symmetry Breaking Phenomenon Caused by a Phase Transition

(2010) Rui Tamura et al.   Symmetry-Basel

Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions

(2009) Matthew W. Powner et al.   NATURE

The Miller Volcanic Spark Discharge Experiment

(2008) A. P. Johnson et al.   SCIENCE