Clinical implication of genetic intratumor heterogeneity for targeted therapy in head and neck cancer
出版年份 2023 全文链接
标题
Clinical implication of genetic intratumor heterogeneity for targeted therapy in head and neck cancer
作者
关键词
-
出版物
ACTA ONCOLOGICA
Volume -, Issue -, Pages 1-9
出版商
Informa UK Limited
发表日期
2023-10-31
DOI
10.1080/0284186x.2023.2272293
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pembrolizumab Alone or With Chemotherapy for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma in KEYNOTE-048: Subgroup Analysis by Programmed Death Ligand-1 Combined Positive Score
- (2022) Barbara Burtness et al. JOURNAL OF CLINICAL ONCOLOGY
- First-in-human study of PC14586, a small molecule structural corrector of Y220C mutant p53, in patients with advanced solid tumors harboring a TP53 Y220C mutation.
- (2022) Ecaterina Elena Dumbrava et al. JOURNAL OF CLINICAL ONCOLOGY
- A transcriptomic map of EGFR-induced epithelial-to-mesenchymal transition identifies prognostic and therapeutic targets for head and neck cancer
- (2022) Henrik Schinke et al. Molecular Cancer
- Intratumor heterogeneity is biomarker specific and challenges the association with heterogeneity in multimodal functional imaging in head and neck squamous cell carcinoma
- (2021) Jacob H. Rasmussen et al. EUROPEAN JOURNAL OF RADIOLOGY
- Intratumoural heterogeneity and clone evolution of oral squamous cell carcinoma
- (2021) Lin Wang et al. MOLECULAR CARCINOGENESIS
- Limited evolution of the actionable metastatic cancer genome under therapeutic pressure
- (2021) Joris van de Haar et al. NATURE MEDICINE
- Chromosomal copy number heterogeneity predicts survival rates across cancers
- (2021) Erik van Dijk et al. Nature Communications
- A Comparison of Tools for Copy-Number Variation Detection in Germline Whole Exome and Whole Genome Sequencing Data
- (2021) Migle Gabrielaite et al. Cancers
- Does multiparametric imaging with 18F-FDG-PET/MRI capture spatial variation in immunohistochemical cancer biomarkers in head and neck squamous cell carcinoma?
- (2020) Jacob H. Rasmussen et al. BRITISH JOURNAL OF CANCER
- TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection
- (2020) Apostolos Klinakis et al. EBioMedicine
- Probability distribution of copy number alterations along the genome: an algorithm to distinguish different tumour profiles
- (2020) Luísa Esteves et al. Scientific Reports
- NOTCH1 Signaling in Head and Neck Squamous Cell Carcinoma
- (2020) Pooja A. Shah et al. Cells
- Intratumor genetic heterogeneity in squamous cell carcinoma of the oral cavity
- (2019) Dan P. Zandberg et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Intratumor heterogeneity of PD-L1 expression in head and neck squamous cell carcinoma
- (2019) Jacob H. Rasmussen et al. BRITISH JOURNAL OF CANCER
- Lessons learned from SMAD4 loss in squamous cell carcinomas
- (2019) Ariel L. Hernandez et al. MOLECULAR CARCINOGENESIS
- The changing therapeutic landscape of head and neck cancer
- (2019) John D. Cramer et al. Nature Reviews Clinical Oncology
- Heterogeneity of the Head and Neck Squamous Cell Carcinoma Immune Landscape and Its Impact on Immunotherapy
- (2019) Madison Canning et al. Frontiers in Cell and Developmental Biology
- Epigenetic Modifications in Head and Neck Cancer
- (2019) Jadwiga Gaździcka et al. BIOCHEMICAL GENETICS
- Assessing reliability of intra-tumor heterogeneity estimates from single sample whole exome sequencing data
- (2019) Judith Abécassis et al. PLoS One
- Comprehensive Genomic Review of TCGA Head and Neck Squamous Cell Carcinomas (HNSCC)
- (2019) Mario Pérez Sayáns et al. Journal of Clinical Medicine
- A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT)
- (2018) J Mateo et al. ANNALS OF ONCOLOGY
- ESCAT: A Step in the Right Direction
- (2018) A J Silver et al. ANNALS OF ONCOLOGY
- The promise of ESCAT: a new system for evaluating cancer drug–target pairs
- (2018) Bishal Gyawali et al. Nature Reviews Clinical Oncology
- Evaluation of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Kinase Inhibitor, in Patients With Advanced Solid Tumors Harboring Genetic Alterations in Fibroblast Growth Factor Receptors: Results of a Global Phase I, Dose-Escalation and Dose-Expansion Study
- (2017) Lucia Nogova et al. JOURNAL OF CLINICAL ONCOLOGY
- SinaPlot: An Enhanced Chart for Simple and Truthful Representation of Single Observations Over Multiple Classes
- (2017) Nikos Sidiropoulos et al. JOURNAL OF COMPUTATIONAL AND GRAPHICAL STATISTICS
- The challenges of tumor genetic diversity
- (2016) Edmund A. Mroz et al. CANCER
- Intra-tumor Genetic Heterogeneity and Mortality in Head and Neck Cancer: Analysis of Data from The Cancer Genome Atlas
- (2015) Edmund A. Mroz et al. PLOS MEDICINE
- Multiple region whole-exome sequencing reveals dramatically evolving intratumor genomic heterogeneity in esophageal squamous cell carcinoma
- (2015) W Cao et al. Oncogenesis
- Tumor Evolution and Intratumor Heterogeneity of an Oropharyngeal Squamous Cell Carcinoma Revealed by Whole-Genome Sequencing
- (2015) Xinyi Cindy Zhang et al. NEOPLASIA
- PTEN Deficiency Contributes to the Development and Progression of Head and Neck Cancer
- (2015) Cristiane H Squarize et al. NEOPLASIA
- Tumour heterogeneity in the clinic
- (2013) Philippe L. Bedard et al. NATURE
- Emerging landscape of oncogenic signatures across human cancers
- (2013) Giovanni Ciriello et al. NATURE GENETICS
- Overexpression of EGFR in Head and Neck Squamous Cell Carcinoma Is Associated with Inactivation of SH3GL2 and CDC25A Genes
- (2013) Guru Prasad Maiti et al. PLoS One
- Copy Number Amplification of the PIK3CA Gene Is Associated with Poor Prognosis in Non-lymph node metastatic Head and Neck Squamous Cell Carcinoma
- (2012) Toshihito Suda et al. BMC CANCER
- Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
- (2012) Marco Gerlinger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Intratumor Heterogeneity: Seeing the Wood for the Trees
- (2012) T. A. Yap et al. Science Translational Medicine
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